Clinical trials: Suffering
Heart Failure, Atrial Fibrillation
Investigation of a Novel Integrated Care Concept (NICC) for Patients Suffering From Chronic Cardiovascular Disease
Cardiovascular diseases are the number 1 cause of death globally and represent a major economic burden on health care systems. The investigators have developed a novel integrated care concept (NICC) which combines telemedicine…
- Conditions
- Heart Failure, Atrial Fibrillation, Treatment Resistant Hypertension
- Trial name
- CardioCare MV (NCT03317951)
- Testing
- Novel integrated care concept (NICC), Standard care
- Where
- Germany
- Volunteers
- 964 people
- Sponsor
- University Medical Center Rostock
Traumatic Brain INjury
Prognostic Potential of Prehospital Biomarkers in TBI Patients
The PreTBI III study aims to investigate the prognostic potential of prehospital and repeated in-hospital S100B, NSE and GFAP measurements as predictors of neurological outcome in patients suffering severe TBI.
- Trial name
- PreTBI III (NCT03062566)
- Testing
- Blood sampling
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Aarhus
Physical Suffering, Post Procedural Discharge
Determining the Severity of Physical Symptoms Displayed and Their Level of Perceived Readiness for Discharge After Birth
H1a: There is a difference between the severity of physical symptoms displayed by puerperal women who received routine and personalized care during the early postpartum period.
- Trial name
- NCT04656756
- Testing
- Personalized Care
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Aysegul Durmaz
Attention Deficit Disorder With Hyperactivity
Effects of Ritalin on Postural Stability of Hyper Active Children
Experimental design overview The proposed project is a prospective experimental study design. Children (age <15) suffer from attention deficit hyperactivity disorder (ADHD) that their Parents willing to participate in the study…
- Trial name
- NCT00485797
- Testing
- Ritalin
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Non-cancer Pain, Opioid Induced Constipation
Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation
The study will evaluate the efficacy, safety and tolerability of prucalopride over 12 weeks of treatment in subjects aged 18 years and older with chronic non-cancer pain, suffering from opioid induced constipation.
- Trial name
- OIC (NCT01117051)
- Testing
- prucalopride
- Where
- Belgium
- Volunteers
- 174 people
- Sponsor
- Shire
Crohn's Disease
A Trial Evaluating Safety of Chronic Therapy With Certolizumab Pegol in Crohn's Disease
The primary aim of this study is allow the patients suffering from Crohn's disease , who both completed the therapeutic confirmatory study C87055 of certolizumab pegol and benefited from the treatment, to receive treatment with…
- Trial name
- NCT00358683
- Testing
- Certolizumab pegol
- Sponsor
- UCB Pharma
Acute Lung Injury
Acute Lung Injury After Allogeneic Transplantation - Diagnosis and Early Treatment
Acute lung injury (ALI) is an early complication after allogeneic transplantation causing significant mortality and morbidity. Little is known on early markers and treatment of this complication.
- Trial name
- NCT00852605
- Testing
- Intermittent Non-Invasive Ventilation
- Volunteers
- 86 people
- Sponsor
- Technische Universität Dresden
Traumatic Brain Injury
Dexanabinol in Severe Traumatic Brain Injury
Each year a large number of patients are hospitalized at Shock Trauma Centers with severe head injuries. Bleeding into and swelling of these patients' brains may cause compression of vital structures, disability and death.
- Trial name
- NCT00129857
- Testing
- Dexanabinol
- Volunteers
- 860 people
- Sponsor
- Pharmos
Neovascular Age-related Macular Degeneration of All Subtypes
Assessment of Early Changes in SD-OCT After Initiation of a Treatment by Intravitreal Aflibercept (EYLEA®)START
Aflibercept (EYLEA®) induces a rapid reduction in central retinal thickness (CRT) for patients suffering from neovascular age-related-macular degeneration.1 This early dramatic reduction in CRT is already observed through week 4.
- Trial name
- START (NCT02246829)
- Testing
- Intravitreal injection
- Where
- 10 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Emotion Regulation, Emotional Disorder
Progression of a Group of Patients Suffering From Emotional Dysregulation But Heterogeneous in Terms of Diagnosis, Benefiting From the DBT Group Programme.
Human beings experience emotions and have the ability to manage them, but when these abilities are undermined by mental illness, the result is emotional dysregulation.
- Trial name
- PEAC-TRE (NCT06577675)
- Testing
- Group programme for DBT training
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Lupus Erythematosus, Systemic
A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Systemic Lupus Erythematous in adult patients with moderate to severe symptoms.
- Trial name
- OPUS-2 (NCT05672576)
- Testing
- Cenerimod
- Where
- 147 sites in United States, Chile and 16 more
- Volunteers
- 451 people
- Sponsor
- Viatris Innovation GmbH
Vulvovaginal Atrophy
Investigation of Efficacy and Tolerability of a Lactic Acid Containing Vaginal Suppository in Post-menopausal Women With VVA
The aim of the study is to investigate the efficacy and tolerability of a lactic acid containing vaginal suppository with respect to the application in post-menopausal women with VVA.
- Trial name
- NCT04222647
- Testing
- WO533
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Dr. August Wolff GmbH & Co. KG Arzneimittel
Osteoarthritis, Knee
Cell-free Stem Cell-derived Extract Formulation for Knee Osteoarthritis
The purpose of this study is to determine the safety and efficacy of intraarticular injection of Cell-free Stem Cell-derived Extract Formulation for treatment of knee osteoarthritis symptoms.
- Trial name
- NCT04971798
- Testing
- Cell-free Stem Cell-derived Extract Formulation (CCM)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- General Therapeutics
Endocrine System Diseases
Growth Retardation In Children With Special Pathological Conditions Or Disease
To show an increase in annual growth rate 3 years after Visit 2. Annual growth rate in standard deviation (SD) after 3 years will be compared to growth rate before the start of GH treatment.
- Trial name
- NCT00163215
- Testing
- Somatropin
- Where
- 18 sites in France
- Volunteers
- 46 people
- Sponsor
- Pfizer
COVID-19
Differences Between Women With COVID-19 and Long Covid
The coronavirus disease of 2019 (COVID-19) has infected more than 630 million people and resulted in more than 6.5 million deaths worldwide.
- Trial name
- NCT05669235
- Testing
- Questionnaires
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- University of Valencia
Tension, Headache
Evaluation of the Impact of the HL Natural, Inc. Tension Relief Product
The primary hypothesis of the present study is that supplementation with the Tension Relief test product will reduce the severity of symptoms of a tension headache.
- Trial name
- NCT04091555
- Testing
- HLNatural Tension
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Hawthorne Effect Inc.
Renal Anemia of Chronic Kidney Disease
A Study of YPEG-rhEPO in Patients Suffered From Anemia Due to Chronic Kidney Disease
The purpose of this study is to evaluate the effectiveness and safety of YPEG rhEPO, a recombinant human erythropoietin pegylated by Y shape polyethylene glycol, in patients with anemia due to Chronic Kidney Disease (CKD)…
- Trial name
- NCT04885647
- Testing
- YPEG-rhEPO
- Where
- 17 sites in China
- Volunteers
- 60 people
- Sponsor
- Xiamen Amoytop Biotech Co., Ltd.
Bone Metastasis
A Study to Collect Data About Analgesia in Patients With Bone Metastasis
Up to 180 patients with bone metastasis and requiring analgesic treatment will be followed during 4 to 10 weeks. All patients will continue to receive their cancer therapeutic treatments and be treated for pain relief exactly as…
- Trial name
- NCT02774213
- Testing
- Questionnaires completion, Clinical Pain Assessments
- Where
- 8 sites in Belgium, France
- Volunteers
- 74 people
- Sponsor
- Tools4Patient
Pain, Urinary Tract Infections
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
This study will evaluate the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as a short term analgesic treatment for the primary symptoms of pain or burning when passing urine associated with…
- Trial name
- NCT01064024
- Testing
- Phenazopyridine Hydrochloride
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Central Precocious Puberty
Efficacy, Safety, and Pharmacokinetics (PK) of Triptorelin 6-month Formulation in Patients With Central Precocious Puberty
The study will investigate the efficacy, safety and pharmacokinetics of triptorelin 22.5 mg 6-month formulation in 44 patients suffering from central precocious puberty.
- Trial name
- NCT01467882
- Testing
- Triptorelin
- Where
- 13 sites in United States, Chile and 1 more
- Volunteers
- 44 people
- Sponsor
- Debiopharm International SA
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