Clinical trials: Sugammadex, Pregnant, Anesthesia
Prostate Hypertrophy, Renal Disease
Effect of Deep BLock on Intraoperative Surgical Conditions
Rationale: A deep neuromuscular block is often associated with improved surgical conditions especially in laparoscopic surgery. However, a deep block comes at the expense of a variety of items that may conflict with the use of a…
- Trial name
- BLISS (NCT01631149)
- Testing
- Surgical block (rocuronium; atracurium/mivacurium)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Leiden University Medical Center
Caesarean Section, Pregnancy
Modern Myorelaxation Procedure and Reversal of Neuromuscular Blockade With General Anesthesia for Caesarean Section
The project aims to introduce into clinical practice for Caesarean section conducted under general anesthesia with the rapid induction myorelaxation with rocuronium and the reversal of neuromuscular blockade by using sugammadex.
- Trial name
- RocSugIO (NCT01718236)
- Testing
- Rocuronium + sugammadex, Succinylcholine + Neostigmine
- Where
- 2 sites in Czechia
- Volunteers
- 500 people
- Sponsor
- Brno University Hospital
Sugammadex, Pregnant, Anesthesia
Sugammadex Administration in Pregnancy
In this study, the investigators aimed to evaluate the maternal and fetal effect of sugammadex in pregnant patients undergoing a non-obstetric surgery.
- Trial name
- NCT05708469
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Sakarya University
Pregnancy
Placental Transfer of Sugammadex in the Human Placental Perfusion Model
Preclinical research raised concern regarding the foetal effects of using sugammadex during pregnancy. However, to the best of our knowledge, the placental transfer of sugammadex has never been measured.
- Trial name
- NCT06634355
- Testing
- Sugammadex
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Neuromuscular Blocking Agents, Urinary Retention After Procedure
NMBA Reversal and Postoperative Urinary Retention
In this single-center retrospective cohort study of adult patients who underwent surgery under general anesthesia at Beth Israel Deaconess Medical Center between September 2016 and January 2024, the association between the choice…
- Conditions
- Neuromuscular Blocking Agents, Urinary Retention After Procedure, Urinary Retention Postoperative, Neuromuscular Blockade Reversal Agent
- Trial name
- NCT06948409
- Testing
- Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist])
- Where
- United States
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center