Clinical trials: Suicidal
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Depressive Disorder, Major, Suicide
Rapid Acting TMS for Suicide Ideation in Depression
This study evaluates the effects of an accelerated schedule of theta-burst stimulation, termed accelerated intermittent theta-burst stimulation (aiTBS), on the neural networks underlying explicit and implicit suicidal cognition…
- Trial name
- NCT05100004
- Testing
- Accelerated Theta Burst Stimulation
- Where
- United States
- Sponsor
- Stanford University
Suicidal Ideation, Major Depressive Disorder
Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation
The purpose of this study is to gather information regarding the use of a new type of transcranial magnetic stimulation (TMS) called theta burst stimulation (TBS) for suicidal ideation in adolescents with Major Depressive…
- Trial name
- NCT04502758
- Testing
- MagVenture TMS Therapy System w/Theta Burst Stimulation
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Mayo Clinic
Suicide, Attempted, Suicidal Ideation
Clinical Decision Support to Prevent Suicide
Suicide kills 132 Americans every day. The first step of suicide prevention is risk identification and prognostication. Researchers like this study team have developed and validated predictive models that use routinely collected…
- Trial name
- CDS_PS (NCT05312437)
- Testing
- Interruptive Alert, CDS, Passive Prompt, CDS
- Where
- United States
- Volunteers
- 596 people
- Sponsor
- Vanderbilt University Medical Center
Suicidal Ideation, Suicide
The Impact of Ketamine on the Reward Circuitry of Suicidal Patients
Every 40 seconds, someone in the world dies by suicide. There is a lack of effective and safe antisuicidal agents for preventing suicide attempts.
- Trial name
- NCT02532153
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Bipolar Disorder (BD), Suicidality
Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression
Bipolar disorder is characterized by manic episodes and episodes of extreme depressive feelings, also known as bipolar depression (BD).
- Trial name
- DEEPP (NCT05177146)
- Testing
- Intravenous Ketamine (IV)
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre for Addiction and Mental Health
Suicide, Suicidal Ideation
Intervening to Reduce Suicide Risk in Veterans With Substance Use Disorders
The purpose of this study is to evaluate the impact of a Cognitive Behavioral Therapy (CBT) intervention compared to a Supportive Psycho-educational Control (SPC) condition in reducing the frequency and intensity of suicidal…
- Conditions
- Suicide, Suicidal Ideation, Substance-Related Disorders
- Trial name
- NCT02439762
- Testing
- Cognitive Behavioral Therapy (CBT), Supportive Psycho-education (SPC)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Michigan
Suicidal Crisis, Psychiatric Disorder
Prevalence of Brief Suicidal Crisis in Psychiatric Settings
France is among the countries with one of the highest suicide rates in the world, far above those of its neighboring countries [Wasserman et al., 2012].
- Trial name
- RBSCP (NCT07740356)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
NSSI
The Muti-centered Investigation，Pathogenesis and Intervention Study of Non-suicidal Self-injury Behavior in China
Non-suicidal self-injury (NSSINSSINSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders.
- Trial name
- NCT04094623
- Testing
- Dialectical behavior therapy, Social support group therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing Medical University
Intoxication, Delirium Tremens (DTs)
Preventox - a Digital Intervention for Patients With Intoxications in Intensive Care
Background and purpose At present, occasional referral to psychiatric or addiction services is the only aftercare option offered following an intoxication/overdose requiring intensive care.
- Conditions
- Intoxication, Delirium Tremens (DTs), Poisoning by Psychoactive Substances, Suicidal Attempt
- Trial name
- NCT07819500
- Testing
- Preventox, a digital self-help tool for patients with intoxications in intensive care., Preventox control group
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Relatives
Family Connections for Caregivers of People With Suicidal Behavior
The aim of our study is to verify the efficacy of the Family Connections intervention for relatives of people diagnosed with suicidal behavior disorder in a randomized control trial with a Spanish participants.
- Trial name
- NCT05157607
- Testing
- Family Connections Protocol for Relatives of Patients with SBD., Treatment as Usual Optimized Protocol (TAU-O)
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Family Conflict, Suicidal Ideation
Early Intervention for Suicide Risk Among Immigrant Youth
The purpose of this project is to develop and test a family-based preventive intervention for suicide risk among 1st and 2nd generation immigrant Latino/a adolescents.
- Trial name
- NCT03221530
- Testing
- Early Intervention for Suicide Risk Among Immigrant Youth, Enhanced usual care
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Suicide, Attempted, Suicidal Ideation
WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt
The goal of this project is to test whether WellPATH-PREVENT (a novel, mobile psychosocial intervention) improves a specific aspect of emotion regulation, i.e., cognitive reappraisal ability, and reduces suicide risk in…
- Conditions
- Suicide, Attempted, Suicidal Ideation, Depression
- Trial name
- NCT05183230
- Testing
- WellPATH-PREVENT, Optimized WellPATH-PREVENT
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- Weill Medical College of Cornell University
Suicidal Ideation
Career Enhancement Training Study (USAF)
A study evaluating a training program to decrease risk for suicidal thoughts and behaviors among early career trainees in the United States Air Force.
- Trial name
- CETS (NCT04067401)
- Testing
- Wingman Connect, Stress Management
- Where
- United States
- Volunteers
- 1,485 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Suicidal Ideation, Self Injurious Behavior Without Suicidal Intent
Experiences of Brief Admission From the Perspective of Family and Significant Others
As a result of a randomized controlled trial (NCT02985047) BA is continuously offered to persons with self-harm at risk for suicide in Skåne, Sweden.
- Conditions
- Suicidal Ideation, Self Injurious Behavior Without Suicidal Intent, Self-Harm, Deliberate
- Trial name
- NCT04962217
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Region Skane
Suicidal Ideation, Attempted Suicide
A Randomized Trial for Suicidal Patients
Although suicide risk is highly prevalent among the patient population in mental health care, remarkably little research exists on effective treatments. Among a small set of novel approaches, CAMS is particularly promising.
- Conditions
- Suicidal Ideation, Attempted Suicide, Suicide
- Trial name
- NCT02685943
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Vestre Viken Hospital Trust
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Suicidal Ideation, Psychological Trauma
Eye Movement Desensitization and Reprocessing (EMDR) for Police Personnel
Objectives: 1. To examine the feasibility of Eye Movement Desensitization and Reprocessing (EMDR) as an intervention to reduce psychological trauma and stress amongst police officers in Pakistan. 2.
- Conditions
- Suicidal Ideation, Psychological Trauma, Stress
- Trial name
- NCT05171868
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR)
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Pakistan Institute of Living and Learning
Major Depressive Episode
Pain Perception in Suicidal Behavior Vulnerability
In France, almost 1 death on 50 is a suicide. The suicide occurs in unbearable psychic pain where mental trouble has a major influence. It is classified as preventable mortality.
- Trial name
- DOCS (NCT02915679)
- Testing
- Blood sample for genetic purpose, psychiatric assessment and pain investigation
- Where
- France
- Volunteers
- 167 people
- Sponsor
- University Hospital, Montpellier