Clinical trials: Suicidal
Self-Injurious Behavior, Self Harm
Treating Self Injurious Behavior: A Novel Brain Stimulation Approach
The purpose of this study is to explore the tolerability and effectiveness of transcranial direct current stimulation (tDCS) as a potential treatment for non-suicidal self-injury (NSSI).
- Conditions
- Self-Injurious Behavior, Self Harm, Self-injury, Self-inflicted Injury
- Trial name
- NCT04244786
- Testing
- Transcranial direct current stimulation, No intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- New York State Psychiatric Institute
Suicidal Ideation, Suicide, Attempted
Establishing Efficacy of an Inpatient Intervention and Phone App to Reduce Suicidal Risk
In this 2-site study, University of Texas Southwestern Medical Center (UTSW) and Western Psychiatric Institute and Clinic (WPIC), the investigators will conduct a randomized clinical trial (RCT) in 240 psychiatrically…
- Trial name
- ASAP+BRITE (NCT03825588)
- Testing
- ASAP (As Safe As Possible), BRITE smart phone app, TAU (treatment as usual)
- Where
- 2 sites in United States
- Volunteers
- 241 people
- Sponsor
- University of Texas Southwestern Medical Center
Major Depressive Disorder, Suicidal Ideation
Ketamine in the Treatment of Suicidal Depression
This study is designed to compare the effectiveness of two medications, Ketamine and Midazolam, for rapidly relieving suicidal thoughts in people suffering from depression.
- Trial name
- NCT01700829
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- New York State Psychiatric Institute
Suicide
Coping Long Term With Attempted Suicide - Adolescents
This study is to develop an adjunctive intervention for acutely suicidal adolescents who have been admitted to a psychiatric inpatient unit.
- Trial name
- CLASP-A (NCT01748760)
- Testing
- CLASP-A intervention, Treatment as Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brown University
Depression, Suicidal Ideation
Screening Wizard, Component 1 of iCHART (Integrated Care to Help At-Risk Teens)-Feasibility/Pilot Phase
Screening Wizard (SW). Primary Care Providers (PCPs) are often uncertain about how to best refer adolescents who screen positive for depression or suicidality.
- Trial name
- NCT03985813
- Testing
- Screening Wizard
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- University of Pittsburgh
Depression, Pregnancy Related
Preventing Depressive Relapse in Pregnant Women With Recurrent Depression
The purpose of this investigation is to conduct a pragmatic effectiveness trial comparing digital mindfulness-based cognitive therapy (MBCT) plus usual care to usual care (UC) only among euthymic pregnant women with recurrent…
- Conditions
- Depression, Pregnancy Related, Antenatal Depression
- Trial name
- NCT03623620
- Testing
- Digital Delivery of Mindfulness-Based Cognitive Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Borderline Personality Disorder, Suicide
Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder
This study will compare the effectiveness of two treatments, dialectical behavior therapy versus fluoxetine with clinical management, for reducing the risk of self-injury and suicidal behavior in people with borderline…
- Trial name
- NCT00834834
- Testing
- Fluoxetine, DBT, Citalopram
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- New York State Psychiatric Institute
Sleep Problem, Suicidal Ideation
Sleep Treatment for Teens
The purpose of this research study is to test a brief (6-session), empirically supported, and highly disseminable version of digital (i.e., smartphone or web-based) cognitive behavioral therapy for insomnia (dCBT-I), called…
- Conditions
- Sleep Problem, Suicidal Ideation, Suicide, Attempted
- Trial name
- NCT05397353
- Testing
- Sleepio (TM)
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Rutgers, The State University of New Jersey
Suicide Prevention
Suicide Prevention Study of VA-BIC in the Veteran Population
The VA is committed to reducing suicide in the U.S. Veteran population. Over 6,000 Veterans die from suicide each year, and this risk is particularly high following a psychiatric hospitalization.
- Trial name
- VA-BIC RCT (NCT04446468)
- Testing
- PEACE, Standard Psychiatric Hospital Discharge Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
Suicide, Suicidal Ideation
TMS for Suicidal Crisis in Active Duty SMs
The purpose of this study is to determine if the use of Transcranial Magnetic Stimulation (TMS) provides rapid reduction and sustained attenuation of suicidal crisis.
- Conditions
- Suicide, Suicidal Ideation, Suicidal Impulses, Suicidal Intention
- Trial name
- TMS4SI (NCT03014362)
- Testing
- Neuronetics NeuroStar XPLOR magnetic stimulator - Active
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Eisenhower Army Medical Center
Depression, Anxiety
Digital Mental Health Service for Non-Treatment Seeking Young Adults
This is a feasibility trial of a personalized 8-week text messaging intervention aimed at young adults (ages 18-25) with depression and anxiety who are not interested in -- or experience barriers to -- receiving traditional…
- Conditions
- Depression, Anxiety, Suicidal Ideation
- Trial name
- NCT04948268
- Testing
- Adaptive messaging intervention, Non-personalized messaging intervention, Coaching
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Suicidal and Self-injurious Behavior
A Feasibility Open Trial of App-Enhanced Brief CBT for Suicidal Inpatients
The purpose of this study is to evaluate the feasibility of integrating Brief Cognitive-Behavioral Therapy (BCBT) counseling with a software application (app) to prevent future suicidal thoughts and behaviors.
- Trial name
- NCT05486091
- Testing
- App-Enhanced Brief Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Hartford Hospital
Self Harm, Depression
Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth
This study is designed to refine and test the efficacy of a computer assisted culturally informed and flexible/adaptive intervention for Latino adolescents for whom self-harm behaviors are a health disparity-specifically, Latinas…
- Conditions
- Self Harm, Depression, Emotion Dysregulation, Suicidal Ideation
- Trial name
- NCT03709472
- Testing
- Computer Assisted CIFFTA, Behavioral: Traditional face-to-face treatment-no technology
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Miami
Suicidal Ideation, Depression
Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse
This project aims to evaluate the potential rapid and sustained antisuicidal and antidepressant effects of a single intranasal dose of ketamine in inpatients during a mood episode in Major Depressive Disorder (MDD) or Bipolar…
- Conditions
- Suicidal Ideation, Depression, Alcohol Abuse
- Trial name
- NCT03539887
- Testing
- Intranasal ketamine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicide, Suicide Prevention
Suicide Prevention Integration Into Task-shifted Mental Health Interventions
Investigators will conduct a pilot clinical trial to assess the feasibility and acceptability of implementing a Suicide Prevention Package (SuPP) within an existing task-shifted depression intervention in rural Pakistan.
- Conditions
- Suicide, Suicide Prevention, Suicidal Ideation
- Trial name
- KPZ (NCT06208293)
- Testing
- KPZ Program (KPZ), Enhanced Usual Care (EUC)
- Where
- Pakistan
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Yale University
Suicidal Ideation
Unique Effects of Perimenstrual Estradiol or Progesterone Supplementation on Perimenstrual Suicidality
This within-person, crossover, 3-condition, placebo-controlled study compares the impact of three perimenstrual conditions on severity of suicidal symptoms in females with past-month suicidality but minimal risk of imminent…
- Trial name
- CLEAR-2 (NCT03498313)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Suicide, Suicide Threat
Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department
Current treatment for acutely suicidal patients are limited to hospitalization, psychotherapy, electro-convulsant therapy, or a combination of the aforementioned. However, this has added to the national boarding problem.
- Conditions
- Suicide, Suicide Threat, Depression Severe
- Trial name
- NCT04260607
- Testing
- Ketamine Hydrochloride, Normal saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Naval Medical Center Camp Lejeune
Suicide, Psychiatric Rehabilitation
ACT for Life: a Brief Intervention for Maximizing Recovery After Suicidal Crises
An estimated 20 Veterans kill themselves every day. Suicide prevention literature and public health policy both call for treatment targeting high-risk populations, such as Veterans hospitalized due to suicidal intent and/or…
- Trial name
- NCT02751983
- Testing
- ACT for Life, Treatment as usual
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation
Career Enhancement Training Study (USAF)
A study evaluating a training program to decrease risk for suicidal thoughts and behaviors among early career trainees in the United States Air Force.
- Trial name
- CETS (NCT04067401)
- Testing
- Wingman Connect, Stress Management
- Where
- United States
- Volunteers
- 1,485 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Suicidal Ideation, Emotions
Dialectical Behavior Therapy Skills Group Pilot Evaluation
Uncontrolled pilot study examines feasibility, acceptability, and preliminary efficacy of Dialectical Behavior Therapy skills group for Veterans with suicidal ideation and emotion dysregulation.
- Trial name
- NCT02499406
- Testing
- Dialectical behavior therapy skills group
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Connecticut Healthcare System