Clinical trials: Suicidal Behavior
Suicide Attempt, Suicidal and Self-injurious Behavior
Suicide Preventive Psychosocial Treatment for Youths
Suicide is the leading cause of death amongst 10-18-year-olds in Sweden. Suicide attempts are the strongest predictor of subsequent death by suicide, often lead to inpatient care, and are associated with substantial societal…
- Conditions
- Suicide Attempt, Suicidal and Self-injurious Behavior, Suicide Attempted, Suicide, Attempted
- Trial name
- NCT06931639
- Testing
- Safe Alternatives for Teens and Youth (SAFETY), Enhanced Treatment As Usual
- Where
- 5 sites in Sweden
- Volunteers
- 282 people
- Sponsor
- Karolinska Institutet
Clinical High Risk for Psychosis (CHR), Suicidal Ideation
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis
Young people at clinical high risk for psychosis are more likely to experience suicide thoughts than the general population, but there are few suicide prevention programs designed specifically for them.
- Conditions
- Clinical High Risk for Psychosis (CHR), Suicidal Ideation, Psychosis, Suicidal Behavior
- Trial name
- NCT07756567
- Testing
- Suicide Prevention Intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Diego
Dialectical Behavior Therapy, Suicidal
Dialectical Behavior Therapy for Adolescent With Repeated Suicidal and Self-harming Behavior in Tanta University Hospitals
The aim of the current study is to:-Evaluate the efficacy of dialectical behavior therapy compared with individual and group supportive therapy for reducing suicide attempts and ideation among adolescence.
- Conditions
- Dialectical Behavior Therapy, Suicidal, Adolescent, Behavior
- Trial name
- NCT07888270
- Testing
- Dialectical Behavior Therapy, Individual and Group Supportive Therapy group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Suicidal Ideation, Suicidal Behavior
Intravenous Ketamine for Acute Suicidal Crisis and Psychiatric Hospital Length of Stay
This randomized, double-blind, active placebo-controlled superiority trial will evaluate whether intravenous esketamine reduces time to psychiatric hospital discharge in adults hospitalized because of acute suicide risk.
- Trial name
- NCT07888933
- Testing
- Esketamine, Midazolam (Intravenous)
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- University of Sao Paulo
PTSD, Suicidal Thoughts and Behaviors
Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
This study will be the first to use brain imaging to explore how cannabis affects the brain and inflammation in U.S. military veterans with PTSD.
- Conditions
- PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
- Trial name
- CNS (NCT07222306)
- Testing
- 1-(2-[+F]fluoroethyl)-L-tryptophan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Adults With Treatment-Resistant Self-Harm and Eating Disorders: Substudy 1
This study aims to evaluate National Highly Specialized Care (NHV) for adults with severe and treatment-resistant self-harm or eating disorders in Sweden.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_ADULTS (NCT07878897)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet
Suicidal Ideas, Suicidal Ideation
Exploratory Analysis of Interpersonal and Intrapersonal Psychological Processes Implied in Risk-taking and Suicidal Behaviors, in Adult and Adolescent At-risk
In a recent report, Santé Publique France (2023), reported that 4.2% of 18-85 year-olds had thought about suicide in the last 12 months, and 6.8% had attempted suicide in their lifetime and 0.5% in the last year.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Risk-taking
- Trial name
- RISKY (NCT06921226)
- Testing
- Psychological Processes, Risk-taking variables, Suicidal ideation and behavior
- Where
- 3 sites in France
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Bipolar Disorder in Remission, Major Depression in Remission
Seasonality, Chronotype, Impulsivity, and Suicidality in Mood Disorder Patients
The aim of the study is to examine the seasonal variation of suicidal ideation in patients with mood disorders and the trajectory of impulsivity and suicidal ideation in patients with higher seasonality.
- Trial name
- NCT07857213
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University - Cerrahpasa
Suicidal Ideation and Behavior, Mood Disorders
Videoconference-Based Brief Cognitive Behavioral Therapy for Patients With Mood Disorders at High Risk for Suicide
This study aims to investigate inflammatory biomarkers associated with suicide risk and to evaluate the efficacy of videoconference-based brief cognitive-behavioral therapy (V-BCBT) in patients with mood disorders at high risk…
- Conditions
- Suicidal Ideation and Behavior, Mood Disorders, Suicide Attempt, Cognitive Behavior Therapy
- Trial name
- V-BCBT-BIO (NCT07857291)
- Testing
- Videoconference-Based Brief Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Hyung Keun Park
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Suicidal Ideation, Circadian Rhythm Disorders
Mind After Midnight
This study examines whether wakefulness during the biological night (2:00-4:00 AM) is associated with increased negative mood, impaired decision-making, and suicidal thoughts.
- Conditions
- Suicidal Ideation, Circadian Rhythm Disorders, Sleep Deprivation, Sleep Wake Disorders
- Trial name
- MaM (NCT07438912)
- Testing
- Sleep Pressure Manipulation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Arizona
Non-suicidal Self-injury (NSSI)
Acceptance and Commitment Therapy-Based Chatbot for Non-suicidal Self-Injury in Adolescents
The purpose of this study is to evaluate the feasibility and effectiveness of a self-guided digital Acceptance and Commitment Therapy (ACT) intervention for adolescents who engage in non-suicidal self-injury (NSSI).
- Trial name
- NCT07848620
- Testing
- ACT-Based Chatbot
- Volunteers
- 100 people
- Sponsor
- Central China Normal University
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Suicidal Ideation and Behaviors, Suicide Attempt
Enhanced Brief CBT for Suicidal Inpatients With Mood Disorders
The goal of this clinical trial is to evaluate whether enhanced brief cognitive behavioral therapy (E-BCBT) can help reduce suicidal thoughts and behaviors among psychiatric inpatients.
- Conditions
- Suicidal Ideation and Behaviors, Suicide Attempt, Cognitive Behavioral Therapy
- Trial name
- E-BCBT (NCT07072845)
- Testing
- Enhanced Brief Cognitive Behavioral Therapy (E-BCBT) for Suicidal Inpatients, Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Hyung Keun Park
Suicide, Suicidal Ideation
Intensive Crisis Intervention
The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric care.
- Conditions
- Suicide, Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm
- Trial name
- ICI (NCT06476886)
- Testing
- Intensive Crisis Intervention (ICI), Adolescent Psychiatric Inpatient Unit (APIU)
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Jennifer Hughes
Suicide, Suicidal Ideation and Behavior
Pilot Study on Follow-Up of (Acutely) Suicidal Individuals From the Flemish Suicide Helpline
This pilot study aims to assess the acceptance, feasibility, and added value of follow-up calls at the suicide helpline, Zelfmoordlijn 1813, in Flanders (Belgium).
- Conditions
- Suicide, Suicidal Ideation and Behavior, Crisis Intervention
- Trial name
- CONT-1813 (NCT07343258)
- Testing
- Callbacks from the Zelfmoordlijn 1813
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide and Self-harm, Suicide
Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Open Trial
The primary aim of the present study is leverage existing infrastructure to develop novel technological features for a novel personalized smartphone intervention system, called the Mobile Application to Prevent Suicide (MAPS)…
- Conditions
- Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05180383
- Testing
- Mobile Application to Prevent Suicide (MAPS)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Butler Hospital
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Suicidal Thoughts and Behaviors
Developing and Testing a Brief, Personalized Intervention for Suicidal Thoughts and Behaviors
Suicide is a leading cause of death in the United States and around the world. Individuals at high-risk for suicide are heterogenous.
- Trial name
- AFSP_PRECISE (NCT07749391)
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Diego