Clinical trials: Suicidal Behaviors
Suicidal Ideation/Behavior
Culturally Centered CBT Protocol for Suicidal Behaviors Among Youth in Mexico City
This NIMH R34 award application proposes to conduct an adaptation, implementation, and pilot testing of the culturally centered CBT protocol, the Socio-Cognitive Behavioral Therapy for Suicidal Behaviors (SCBTSB), among suicidal…
- Trial name
- NCT06885047
- Testing
- Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as usual
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Bradley Hospital
Suicidal and Self-injurious Behavior, Linkage to Care
An Adaptive Intervention to Increase Engagement to Community-Based Care After an ED Admission
The goal of this study is to develop a feasible brief, family-based adaptive intervention, via SMART design, for youth with suicidal and non-suicidal self-injurious behavior (SSIB) to increase community-based mental health (MH)…
- Trial name
- ED_SMART (NCT07092345)
- Testing
- adaptive intervention
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Rhode Island Hospital
Suicidal Ideation, Depressive Symptoms
Task-Shifting Adapted IPT-A for Youth Suicide Prevention
The goal of this randomized pragmatic clinical trial is to examine the feasibility, acceptability, and mechanisms of change of a brief adaptation of Interpersonal Psychotherapy for Adolescents (BIPT-A), adapted and task-shifted…
- Conditions
- Suicidal Ideation, Depressive Symptoms, Adolescent Mental Health
- Trial name
- NCT07383831
- Testing
- Adapted Brief Interpersonal Psychotherapy for Adolescents (IPT-A LAZOS), Usual Community Center Services
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Boston College
Suicidal Behavior
Brief Intervention and Contact Program Main Trial
Suicide is a significant public health concern and causes approximately 1.5% of all deaths in the general population in Canada. Research shows that for individuals with comorbid psychiatric illness and suicidal behaviour, the…
- Trial name
- BIC (NCT05656781)
- Testing
- Brief Intervention and Contact (BIC) based on Word Health Organization (WHO)
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Suicide, Nurse's Role
Nurse Suicide: Physiologic Sleep Health Promotion Trial
The purpose of this study is to identify factors (sleep, psychiatric characteristics, stressful life events, and work environment characteristics) that potentiate or mitigate adverse effects of real-world stressors that…
- Conditions
- Suicide, Nurse's Role, Work Environment Adverse Effects, Sleep
- Trial name
- NCT06079853
- Testing
- PureSomni Sleep Health Product Kit
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Columbia University
Substance Abuse, Suicide
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Suicide is the 10th leading cause of death for Americans of all ages and more people in the United States now die from suicide than die from car accidents.
- Conditions
- Substance Abuse, Suicide, Depression
- Trial name
- NCT05489042
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Distress; Maternal, Self Efficacy
Integrated Intervention for Caregivers--Pilot RCT
Adolescents who have been hospitalized for suicidal behavior are at risk for engaging in additional suicidal behavior. After hospitalization, parents or guardians are typically asked to be responsible for helping to prevent…
- Conditions
- Distress; Maternal, Self Efficacy, Parenting, Suicide
- Trial name
- NCT03487627
- Testing
- Electronic and Care Support Manager Contact, Enhanced Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wake Forest University Health Sciences
Adverse Mental/Physical Effects of Low Dose S. Tortuosum.
Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals
Phosphodiesterase is a candidate for the Rx \& prevention of cognitive and psychotic disorders. Since caffeine targets primarily PDE4(Phosphodiesterase subtype 4), caffeine analogs have been developed to mimic the actions of…
- Trial name
- NCT01805518
- Testing
- Scelectium Tortuosum
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Woodbury, Michel, M.D.
Suicide, Depression
Engaging Suicidal Patients in Mental Health Treatment
The investigators will identify characteristics of suicidal patients who do or do not attend a first mental health visit following referral using administrative data.
- Conditions
- Suicide, Depression, Mental Health Impairment, Suicidal Ideation
- Trial name
- NCT05021224
- Testing
- Caring Contacts, Reminders, Informational Poster
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Suicide
Coping Long Term With Attempted Suicide - Adolescents
This study is to develop an adjunctive intervention for acutely suicidal adolescents who have been admitted to a psychiatric inpatient unit.
- Trial name
- CLASP-A (NCT01748760)
- Testing
- CLASP-A intervention, Treatment as Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brown University
Major Depressive Disorder (MDD), Suicidal Ideation
Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk
The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts.
- Trial name
- NCT07025720
- Testing
- TMS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Depression, Mental Illness
Group Interventions for Suicidal African Americans
The investigator is conducting a hybrid efficacy-effectiveness randomized controlled trial with low-income African American suicide attempters.
- Conditions
- Depression, Mental Illness, Suicide, Suicidal Ideation
- Trial name
- NCT02227160
- Testing
- 10 weekly group meetings, Outpatient counseling and support groups
- Where
- United States
- Sponsor
- Emory University
Psychological Disease, Depression
The Dual Factor Model of Mental Health in Inpatients
The Dual Factor Model of mental health (DFM; Greensporn \& Saklofske, 2001) postulates that mental health consists of two at least partially unrelated factors, the experience or absence of psycho-pathological symptoms (i.e.
- Trial name
- NCT04450238
- Testing
- Routine care inpatient treatment
- Where
- Germany
- Volunteers
- 1,552 people
- Sponsor
- Ruhr University of Bochum
Major Depressive Disorder, Bipolar I Disorder
Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression.
Depression and suicidal ideation/attempt/death are major causes of morbidity and mortality from psychiatric illnesses. In 2009, the World Health Organization listed depression as the leading cause of years lost due to disability…
- Conditions
- Major Depressive Disorder, Bipolar I Disorder, Bipolar II Disorder, Bipolar Depression
- Trial name
- NCT02593643
- Testing
- Ketamine, Midazolam, Treatment as usual (TAU)
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Sunnybrook Health Sciences Centre
Suicidal Ideation
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a study group of 150 civilian and Veteran participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Trial name
- PRE-EMPT (NCT07484906)
- Testing
- fMRI Neurofeedback, Accelerated theta burst stimulation, Psilocybin assisted therapy
- Sponsor
- University of New Mexico
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
The goal of this pilot study is to develop and implement a larger scale, multi-site stepped collaborative care trial that targets injured patients with presentations of posttraumatic stress disorder (PTSD) and related…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02335125)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Psychotropic Drugs
- Volunteers
- 40 people
- Sponsor
- University of Washington
Suicidal Ideation, Mental Health Issue
Intensive Case Management Between VA and Community Care for Suicide Prevention
The goal of this randomized clinical trial is to build the evidence base for SUPERCEDE, a suicide prevention focused intensive case management intervention to increase access, improve care coordination, provide suicide prevention…
- Conditions
- Suicidal Ideation, Mental Health Issue, Social Determinants of Health
- Trial name
- SUPERCEDERCT (NCT07534358)
- Testing
- SUicidE PRevention intensive CasE management and coorDination in Community CarE (SUPERCEDE), Present centered therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Eastern Colorado Health Care System
Depression, Suicidal Ideation
Text2Connect, Component 2 of iCHART (Integrated Care to Help At-Risk Teens)
This study proposes to develop and examine a personalized, text-based intervention designed to improve engagement with mental health (MH) treatment.
- Trial name
- T2C (NCT03982043)
- Testing
- Text2Connect
- Where
- 4 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Pittsburgh
Insomnia, Suicidal Ideation
RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts
There is a strong association between insomnia and suicidal thoughts and behaviors. Insomnia also frequently co-occurs with other common conditions associated with suicide such as depression and posttraumatic stress disorder.
- Trial name
- NCT03603717
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
- Where
- 3 sites in United States
- Volunteers
- 283 people
- Sponsor
- VA Office of Research and Development
Suicide
A Pilot Evaluation of a Digital Peer Support Intervention for Suicidal Adolescents
Suicide risk has increased among youth in underserved communities, where access to mental healthcare is limited. To address this need, the investigator team plans to evaluate the preliminary efficacy of a brief, low-cost…
- Trial name
- SWEEP (NCT06349915)
- Testing
- Supporting Wellbeing with Everyday Experiences of Peers (SWEEP)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Albert Einstein College of Medicine