Clinical trials: Suicidal Behaviour, open to volunteers
Self Harm, Suicide, Attempted
Emotional Dysregulation in Para-suicidal Behavior
This is a naturalistic cohort pre-post study investigating aspects of emotional processing and how possible changes in emotional processing is related to the successful treatment of non-suicidal self-injury and suicidal ideation…
- Conditions
- Self Harm, Suicide, Attempted, Emotional Instability, Borderline Personality Disorder
- Trial name
- NCT03846375
- Testing
- Psychotherapy, Pre-intervention testing
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Depressive Disorder, Major Depressive Disorder
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
The purpose of this study is to test the hypothesis that the anti-depressant and anti-suicidal effects of the N-methyl-D-aspartate receptor (NMDAR) antagonist Ketamine is critically dependent on stimulation of…
- Conditions
- Depressive Disorder, Major Depressive Disorder, Bipolar Disorder, Post Traumatic Stress Disorder
- Trial name
- NCT05786066
- Testing
- Perampanel 6 MG, Ketamine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Suicidal Thoughts and Behaviors, Major Depressive Episode (MDE)
Biomarker Discovery for Suicide Precision Circuit Therapeutics
This is a prospective observational biomarker study assessing changes in clinical, behavioral, neuroimaging, and neurophysiological measurer following ketamine/esketamine or electroconvulsive therapy (ECT) in adults with suicidal…
- Trial name
- NCT07723066
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Suicide, Suicidal Ideation
Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care
The overall aim of this study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This study will compare the effectiveness of two brief suicide prevention interventions that have been adapted for use…
- Trial name
- NCT05869552
- Testing
- STAT-PC, YST-III
- Where
- 3 sites in United States
- Volunteers
- 1,485 people
- Sponsor
- Elizabeth Arnold
Suicidal Ideation, Major Depressive Episode
Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode
This study aims at investigating if adjunctive buprenorphine at low dose to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode, and at determining the most effective dose.
- Trial name
- BUPRIS (NCT03646058)
- Testing
- Buprenorphine
- Where
- 9 sites in France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Suicide
Ketamine & Crisis Response Plan for Suicidal Ideation in the ED
The goal of this randomized pilot trial is to assess the feasibility of administering a combination of 100mg intramuscular (IM) ketamine and Crisis Response Plan (a short psychosocial intervention) for patients with acute…
- Trial name
- NCT05696691
- Testing
- Ketamine Hydrochloride, Crisis Response Plan
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Depression, Major Depressive Disorder
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
In this research study, investigators examine how brain activity changes during tests of emotional processing, attention, and memory using multimodal neuroimaging methods including electroencephalography (EEG), functional…
- Conditions
- Depression, Major Depressive Disorder, Suicidal Ideation
- Trial name
- NCT05977439
- Testing
- Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Suicide, Suicidal Ideation
Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago
Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today.
- Conditions
- Suicide, Suicidal Ideation, Suicide Attempt
- Trial name
- SP-BSC (NCT07125144)
- Testing
- Black Youth Suicide Prevention in Chicago, Signs of Suicide: Standard/Existing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Suicidal, Suicide, Attempted
Improving Coping to Reduce Suicide Risk Following ED Discharge
The researchers hope to learn whether an electronic safety plan (ESP) and a supportive text messaging program are feasible and acceptable to adult patients with recent suicidal thoughts or behavior after emergency department (ED)…
- Conditions
- Suicidal, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT06614946
- Testing
- Electronic Safety Plan (ESP), Text support
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Suicide, Suicide Attempt
Suicidal Ideation Framework: Grounded Theory Study, Catalonia
This doctoral project aims to develop a comprehensive theoretical model of the process through which the suicidal ideation framework is configured as a symbolic, narrative, and relational expression, adopting a multiperspective…
- Conditions
- Suicide, Suicide Attempt, Suicide Ideation, Suicide Risk
- Trial name
- SUIF-GT-CAT (NCT07284238)
- Testing
- In-Depth Qualitative Interview, Discussion Group
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester
Non-suicidal Self-injury (NSSI)
Non-Suicidal Self-Injury Digital Psychotherapy Trial
The goal of this randomized, parallel-controlled clinical trial is to investigate multi-dimensional biomarkers (blood, brain imaging, clinical information, and symptom assessment) in adolescents with Non-Suicidal Self-Injury…
- Trial name
- NSSI-DPT (NCT07683234)
- Testing
- digital psychotherapy, Treatment as Usual (TAU)
- Volunteers
- 110 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Suicide Attempts, Suicidal Ideation
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.
- Conditions
- Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
- Trial name
- ASSIST (NCT05078970)
- Testing
- Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Anxiety, Suicidal Ideation
Climate Anxiety in a Young Population at Risk of Suicide
Climate change has become a major source of concern, particularly among younger generations who are facing the progressive degradation of ecosystems, loss of biodiversity, and alarming environmental information disseminated…
- Conditions
- Anxiety, Suicidal Ideation, Mental Health Issue, Environmental Exposure
- Trial name
- Anx-RS (NCT07305688)
- Testing
- Columbia Suicide Severity Rating Scale, Climate Change Anxiety Scale - French version, State-Trait Anxiety Inventory, French version
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Esquirol
Suicidal Thoughts and Behaviors
Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention
Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual.
- Trial name
- NCT06809348
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Suicidal Ideation and Behavior
Adapting Youth Nominated Support Team (YST) to Prevent Suicide
The goal of this study is to conduct a pilot test of a mental health support program called the Youth-Nominated Support Team - Probation (YST-P) for young people ages 12-17 on probation, experiencing suicidal ideation and…
- Trial name
- NCT07559955
- Testing
- Youth-Nominated Support Team for Probation
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Columbia University
Depression, Suicidality
Assessing Improvements in Mood and Sleep Trial
This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt).
- Conditions
- Depression, Suicidality, Sleep
- Trial name
- AIMS (NCT06639477)
- Testing
- Treatment As Usual, Active Condition, Active Comparator
- Where
- 3 sites in United States
- Volunteers
- 420 people
- Sponsor
- University of Pittsburgh
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Suicidal Ideation, Suicide Risk
A Text-Based Expressive Writing Program for Adolescents at Risk of Suicide
The goal of this clinical trial is to learn if a structured expressive writing program can help reduce suicidal thoughts in adolescents and young adults who have experienced suicidal thoughts, suicide attempts, or self-harm.
- Conditions
- Suicidal Ideation, Suicide Risk, Self-Injurious Behavior, Adolescent Mental Health
- Trial name
- WRITE-SAFE (NCT07479823)
- Testing
- Structured Expressive Writing Intervention, Treatment as Usual (TAU)
- Volunteers
- 160 people
- Sponsor
- Hallym University Medical Center
Suicide, Attempted, Suicidal Ideation
Brief Cognitive Behavioral Therapy Replication Trial
The overall goal for the proposed project is to test the effectiveness of BCBT for the prevention of suicide attempts in a sample of treatment-seeking U.S. military personnel and veterans.
- Trial name
- NCT03769259
- Testing
- Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT), Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Utah