Clinical trials: Suicidal Behaviour
Suicidal Ideation
Peer Mentorship to Reduce Suicide Risk Following Psychiatric Hospitalization
Every year in the United States about 1 million people make a suicide attempt and more than 38,000 die by suicide. The risk of suicide is highest among individuals with mental illness who have been hospitalized due to suicidal…
- Trial name
- NCT02365116
- Testing
- Peer mentorship, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- University of Michigan
Suicidal Ideation, Attempted Suicide
A Randomized Trial for Suicidal Patients
Although suicide risk is highly prevalent among the patient population in mental health care, remarkably little research exists on effective treatments. Among a small set of novel approaches, CAMS is particularly promising.
- Conditions
- Suicidal Ideation, Attempted Suicide, Suicide
- Trial name
- NCT02685943
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Vestre Viken Hospital Trust
Suicide, Attempted, Suicidal Ideation
Natural History of Hopelessness, Suicidality, and Optimism in Psychiatric Inpatients Following Discharge
Specific aim #1: To assess the study team's ability to recruit subjects in this cohort and to successfully complete follow-up assessments by phone or mail.
- Trial name
- NCT01599247
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation, Major Depressive Episode
Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode
This study aims at investigating if adjunctive buprenorphine at low dose to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode, and at determining the most effective dose.
- Trial name
- BUPRIS (NCT03646058)
- Testing
- Buprenorphine
- Where
- 9 sites in France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Autism Spectrum Disorder, Depression
Group Depression Treatment for Autistic Youth
Higher rates of depression are reported by autistic adolescents as compared to their non-autistic peers, which is problematic given adverse outcomes (e.g., negative self-esteem, lower academic performance) that are associated…
- Conditions
- Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
- Trial name
- NCT05430022
- Testing
- Autism-adapted Group Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University Medical Center
Suicide, Attempted
Family Intervention for Suicidal Youth: Emergency Care
This project evaluates a brief intervention in the emergency department (ED) for adolescents presenting with suicide attempts. The intervention aims to capitalize on the opportunity offered by the ED visit to deliver an effective…
- Trial name
- FISP (NCT00558805)
- Testing
- FISP + Usual Care, Usual Care
- Where
- 2 sites in United States
- Sponsor
- Centers for Disease Control and Prevention
Suicide
Developing Adaptive Interventions for Suicidal College Students Seeking Treatment - SMART
This pilot study tested the feasibility of utilizing an adaptive intervention strategy for college students who are suicidal when first seeking treatment at a campus clinic.
- Trial name
- SMART (NCT02442869)
- Testing
- Stage 1 Treatment as usual (TAU), Stage 1 CAMS, Stage 2 CAMS
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Nevada, Reno
Reduction in Mental Health and Suicide Are the Focus of Interest, Four Assessment Time Points Would be Used to Monitor Participants Through a Laid Down Conditions
Cognitive Resilience Intervention as a Recovery Therapy for Mental Health
The goal of this randomized controlled trial (RCT) is to develop and test a cognitive resilience intervention (CRI) among selected students who are having problems with anxiety, depression, and suicidal thoughts (psychological…
- Trial name
- CRI (NCT06123442)
- Testing
- Cognitive Resilience Intervention
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Suicide, COVID-19
Qualitative Study of Suicidal Recrudescence Among Adolescents in November 2021
A qualitative study, combining psychiatric and anthropological perspectives, focused on the lived experiences of patients who had recourse to HPNCL emergencies during the period of November 2021, as well as the experiences and…
- Trial name
- Suicide-Covid (NCT05795894)
- Testing
- STAI-Y, BDI scale, M.I.N.I.Kid
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondation Lenval
Prevention of Suicidal Behavior
Impact of a High-resolution Program for the Prevention of Suicidal Behavior in At-risk Adults: a Quasi-experimental Ambispective Cohort Study
Background: Suicidal behavior represents a major public health problem worldwide. According to the World Health Organization (WHO), approximately 720.000 people die by suicide annually, and many more attempt it.
- Trial name
- NCT07655986
- Testing
- PPS; SUICIDE PREVENTION PROGRAM
- Where
- Spain
- Volunteers
- 198 people
- Sponsor
- University of Salamanca
Suicide, Depression
Engaging Suicidal Patients in Mental Health Treatment
The investigators will identify characteristics of suicidal patients who do or do not attend a first mental health visit following referral using administrative data.
- Conditions
- Suicide, Depression, Mental Health Impairment, Suicidal Ideation
- Trial name
- NCT05021224
- Testing
- Caring Contacts, Reminders, Informational Poster
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depression, Suicidal Ideation
Emergency Ketamine Treatment of Suicidal Ideation
The objective of the current program of research will be to test whether intranasal ketamine treatment is more effective than placebo in reducing suicidal ideation in suicidal patients presenting for acute treatment in emergency…
- Conditions
- Depression, Suicidal Ideation, Suicidal Impulses
- Trial name
- NCT02183272
- Testing
- Intranasal Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Major Depressive Disorder
Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk
Joiner's interpersonal theory of suicide postulates that the wish of death comes from feelings of perceived burdensomeness and thwarted belongingness.
- Trial name
- R2D2 (NCT04461327)
- Testing
- Painful stimulations of major depressive patients, Blood sample, Clinical assessment
- Where
- 2 sites in France
- Volunteers
- 144 people
- Sponsor
- University Hospital, Montpellier
Major Depressive Disorder
Trial of a Positive Psychology Intervention in Major Depressive Disorder
In this study, the investigators will perform an exploratory randomized trial of Positive Psychology (PP). The trial will consist of 50 participants and will compare the impact of a phone-based PP intervention vs.
- Trial name
- HOPE (NCT02004145)
- Testing
- Positive Psychology, Control Condition
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation
Think Life, an Online Self-help Intervention for Coping With Suicidal Ideation
The objective of the Think Life study is to test the effect of an online, unguided self-help intervention, i.e. Think Life. The primary hypothesis is that Think Life will reduce suicidal ideation.
- Trial name
- NCT03209544
- Testing
- Online self-help intervention
- Volunteers
- 724 people
- Sponsor
- University Ghent
Suicidal Ideation and Behavior
Suicide Treatment and Recovery in Integrated Behavioral Health (STRIBH)
The suicide rate has increased 28% over the past two decades while heart disease, diabetes, and cancer mortality has declined. Starting in 2011, new standards have led to improved adoption and reach of suicide risk surveillance…
- Trial name
- STRIBH (NCT06700993)
- Testing
- Treatment as Usual in Collaborative Care or Integrated Behavioral Health, Connections model
- Sponsor
- University of Washington
Suicidal Ideation, Suicide Attempt
Real-time Intervention for Suicide Risk Reduction
The aim of this study is to determine whether learning three skills for managing negative emotions and receiving reminders via smartphone to practice these skills reduces how often and how intensely one experiences emotional…
- Trial name
- NCT05848089
- Testing
- Brief skills sessions plus EMI skills practice prompts, Ecological momentary assessment (EMA), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder, Depression
Nitrous Oxide- Suicidal Ideation
Most clinical major depression responds to standard treatments (medication and psychotherapy); however, a significant subset of depressed patients (15-20%) do not respond to these treatments and are referred to as…
- Conditions
- Major Depressive Disorder, Depression, Mood Disorders, Suicidal Ideation
- Trial name
- NCT03736538
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Borderline Personality Disorder
Magnetic Seizure Therapy for the Treatment of Borderline Personality Disorder
Suicide is a major public health crisis for which effective new interventions are needed. An innovative new brain stimulation technique called magnetic seizure therapy (MST) shows promise for treating suicidal thinking in…
- Trial name
- NCT03361826
- Testing
- MagPro MST with Cool TwinCoil, DBT
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Centre for Addiction and Mental Health
Epilepsy
WEUKBRE5557: IMI PROTECT(Work Package 2): Antiepileptics & Suicide
The studies described in this protocol are all performed within the framework of PROTECT (Pharmacoepidemiological Research on Outcomes of Therapeutics by a European ConsorTium) Workpackage 2 and Workgroup 1.
- Trial name
- NCT01607333
- Testing
- Lamotrigine use
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline