Clinical trials: Suicidal Behaviour, active
Non Suicidal Self Injury, Cognitive Behavior Therapy
Evidence-based Digital CBT for Nonsuicidal Self-Injury
To evaluate if evidence-based digital cognitive behaviour therapy for adolescents is an efficacious treatment when delivered as an adjunctive treatment to treatment as usual, compared to a control group consisting of treatment as…
- Trial name
- NCT07337473
- Testing
- Evidence-based digital cognitive behaviour therapy, Health Education
- Volunteers
- 100 people
- Sponsor
- Peking University Sixth Hospital
Suicide Prevention, User Experience
Evaluation of the Quality of Chat Conversations With the Suicide Helpline Zelfmoordlijn 1813
Suicide remains a serious public health issue in Flanders. Every day, nearly three people die by suicide, and many more attempt it or struggle with suicidal thoughts.
- Conditions
- Suicide Prevention, User Experience, Suicide, Suicidal Ideation
- Trial name
- CHATQ-1813 (NCT07176156)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- University Ghent
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Injury, Depression - Major Depressive Disorder
- Trial name
- NCT07717866
- Testing
- Magnetic e-Resonance Therapy (MeRT), Ibogaine Hydrochloride with Magnesium Sulfate, 5-methoxy-N,N-dimethyltryptamine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Axial Therapeutic Research
Suicidal Ideation, Suicide Attempt
A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among…
- Trial name
- NCT06686901
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation, Eating Disorder Symptom
Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates
Project RISE is a randomized control trial. The intervention consists of four modules that focus on multiple aspects of interoception including: body awareness, body sensations/movement, eating, health and self-care, emotional…
- Trial name
- RISE (NCT05285111)
- Testing
- Reconnecting to Internal Sensations and Experiences, Healthy Habits
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Auburn University
Suicidal Ideation, Suicide Risk
A Text-Based Expressive Writing Program for Adolescents at Risk of Suicide
The goal of this clinical trial is to learn if a structured expressive writing program can help reduce suicidal thoughts in adolescents and young adults who have experienced suicidal thoughts, suicide attempts, or self-harm.
- Conditions
- Suicidal Ideation, Suicide Risk, Self-Injurious Behavior, Adolescent Mental Health
- Trial name
- WRITE-SAFE (NCT07479823)
- Testing
- Structured Expressive Writing Intervention, Treatment as Usual (TAU)
- Volunteers
- 160 people
- Sponsor
- Hallym University Medical Center
Suicidal Ideation, Suicide Prevention
User Evaluation Think Life
This study aims to evaluate user experiences with the online self-help course Think Life, a suicide prevention intervention for individuals experiencing suicidal thoughts.
- Conditions
- Suicidal Ideation, Suicide Prevention, mHealth Intervention
- Trial name
- NCT07654127
- Testing
- Self-help course Think Life
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicidal Thoughts and Behaviors
Standardized Adaptive Music Medicine for Suicidality
The primary goal of this clinical trial is to test if music-based intervention (STAMM-S) works for individuals with suicidal thoughts or behaviors.
- Trial name
- STAMM-S (NCT07610785)
- Testing
- STAMM-S
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Military Transition, Community Reintegration
Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans
The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life.
- Conditions
- Military Transition, Community Reintegration, Mental Health, Suicidal Ideation
- Trial name
- NCT06778278
- Testing
- Transition Health and Resilience through Valued Experiences (THRiVE) Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- RTI International
Suicidal Ideation and Behavior, Mood Disorders
Videoconference-Based Brief Cognitive Behavioral Therapy for Patients With Mood Disorders at High Risk for Suicide
This study aims to investigate inflammatory biomarkers associated with suicide risk and to evaluate the efficacy of videoconference-based brief cognitive-behavioral therapy (V-BCBT) in patients with mood disorders at high risk…
- Conditions
- Suicidal Ideation and Behavior, Mood Disorders, Suicide Attempt, Cognitive Behavior Therapy
- Trial name
- V-BCBT-BIO (NCT07857291)
- Testing
- Videoconference-Based Brief Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Hyung Keun Park
Insomnia, Suicidal Ideation
Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change…
- Conditions
- Insomnia, Suicidal Ideation, Suicide, Attempted
- Trial name
- TAILOR (NCT05390918)
- Testing
- TAILOR, Enhanced Usual Care
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Jeff Bridge
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Autism Spectrum Disorder, Major Depressive Disorder
rTMS for Depression in Young Adults With Autism
The current clinical trial is focused on evaluating the efficacy of rTMS for treatment of depression in youth and young adults (hereafter called transition aged youth, TAY) with autism spectrum disorder (ASD).
- Trial name
- rTMS-MDD (NCT04972136)
- Testing
- Active Bilateral Theta Burst Stimulation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre for Addiction and Mental Health
Suicidal Thoughts, Sexual and Gender Minorities
Piloting a Brief, Online Intervention for Suicidality in Sexual and Gender Minority Youth
Sexual and gender minority youth (i.e., LGBTQ+ individuals) are at elevated risk for suicidal thoughts compared to cisgender/heterosexual youth and there is increased demand for programs and treatments tailored to this…
- Conditions
- Suicidal Thoughts, Sexual and Gender Minorities, Youth
- Trial name
- NCT07402265
- Testing
- KindMind
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Western University
Suicide
Mobile Intervention for Suicidal Thoughts
One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions that been associated with suicide risk among military personnel.
- Trial name
- NCT06593379
- Testing
- Safety planning, Treatment as usual, MIST Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Borderline Personality Disorder, Borderline Personality Pathology
ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder
ADEPT is an open-label proof-of-concept study evaluating the safety and tolerability of psilocybin-assisted therapy in conjunction with Dialectical Behavior Therapy for participants with borderline personality disorder.
- Conditions
- Borderline Personality Disorder, Borderline Personality Pathology, Depressive Symptoms, Emotion Dysregulation
- Trial name
- ADEPT (NCT07833761)
- Testing
- Psilocybin, Psilocybin-Assisted Therapy With Dialectical Behavior Therapy
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- University of Minnesota
Suicidal Ideation, Suicide Attempt
Teen Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- Teen RISE (NCT07170657)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
PTSD, Suicidal Ideation
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD).
- Conditions
- PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
- Trial name
- NCT06285708
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Suicide
Just-in-time Interventions for Reducing Short-term Suicide Risk
The goal of this study is to test the effects of just-in-time intervention strategies aimed to promote implementation of the safety plan and its components at different levels of suicidal urges and intent.
- Trial name
- NCT05793541
- Testing
- Phone call, Text messaging, Automated interactive smartphone-based tool
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Massachusetts General Hospital