Clinical trials: Suicidal Depression
Depression, Anxiety
Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health
This project aims to enhance AN university students' behavioral health by supporting their cultural identity development. While the connection between cultural identity and behavioral health is becoming clearer, comparably less…
- Conditions
- Depression, Anxiety, Suicidal Ideation, Substance Use
- Trial name
- NCT04561544
- Testing
- Knowing Who You Are (Becoming): Cultural Identity Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Glioblastoma (GBM)
Mental Health and Suicidality in Glioblastoma Patients in Germany
The aim of the study is to use standardized questionnaires to systematically record influencing factors or predictors for suicidal behavior in glioblastoma patients, particularly with regard to existing depression and anxiety…
- Trial name
- SHINE-GLIO (NCT07409584)
- Testing
- Medical history, physical examination, completing questionnaires, data collection
- Where
- 6 sites in Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital, Essen
Non Suicidal Self Injury, Suicidal Ideation
aiTBS for NSSI and Suicide in Adolescent Depression
Repetitive transcranial magnetic stimulation (rTMS) has been successfully used to help patients with treatment resistant depression.
- Conditions
- Non Suicidal Self Injury, Suicidal Ideation, Suicide and Self-harm
- Trial name
- NCT06210100
- Testing
- Active iTBS
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Central South University
Depressive Disorder, Generalized Anxiety Disorder
Qualitative Study of Student Financial Insecurity and Psychiatry
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and…
- Conditions
- Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation
- Trial name
- QUALIPEPSY (NCT07719816)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depressive Disorder (MDD), Suicidal Ideation
Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation
Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).
- Conditions
- Major Depressive Disorder (MDD), Suicidal Ideation, Hospitalization in Children
- Trial name
- IMPACT-D (NCT07217444)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicide Risk
MIN PLAN VS CBT for Suicide Prevention
1. To investigate the effectiveness of Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP) in University students with Suicide Risk 2.
- Trial name
- NCT05095233
- Testing
- Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP), Min Plan Tool
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Syeda AYAT E ZAINAB Ali
PTSD, PTSD - Post Traumatic Stress Disorder
Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a cohort of 150 participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Conditions
- PTSD, PTSD - Post Traumatic Stress Disorder, Major Depression, Suicidality
- Trial name
- PRE-EMPT (NCT07745569)
- Testing
- Transcranial Magnetic Stimulation, Psilocybin (drug), Neurofeedback
- Volunteers
- 150 people
- Sponsor
- University of New Mexico
Suicide, Attempted, Suicide, Ideation
Relapse Prevention for Suicidal Dually Diagnosed Youths
The purpose of this study is to develop, refine, and pilot test an augmenting cognitive behavior relapse prevention intervention (CBT-RP) for suicidal, depressed, and alcohol/substance abusing adolescents.
- Conditions
- Suicide, Attempted, Suicide, Ideation, Depression, Substance Abuse
- Trial name
- CBT-RP (NCT00589641)
- Testing
- CBT-RP (relapse prevention) + Enhanced TAU, Enhanced TAU Alone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Duke University
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Major Depressive Disorder With Suicidal Ideation With Intent
Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent
Study of efficacy and safety of MIJ821 in addition to comprehensive standard of care on the rapid reduction of symptoms of Major Depressive Disorder (MDD) in subjects who have suicidal ideation with intent
- Trial name
- NCT04722666
- Testing
- MIJ821 Intravenous Injection
- Where
- 39 sites in United States, Argentina and 12 more
- Volunteers
- 199 people
- Sponsor
- Novartis Pharmaceuticals
Suicide, Suicidal Ideation
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED).
- Conditions
- Suicide, Suicidal Ideation, Depression
- Trial name
- NCT06085937
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Lindsay Maguire, MD
Major Depressive Disorder
miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome
The purpose of this study is to examine whether neural-derived exosomal miRNAs are differentially expressed that are specific to suicidal ideation or behavior, and which by affecting specific miRNA targets and pathways, are…
- Trial name
- NCT02418195
- Testing
- ketamine
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Depression, Suicidal Ideation
Text 2 Connect- Texting Intervention for Mental Health Treatment Utilization
Text2Connect (T2C) proposes to test a text-based intervention designed to improve engagement with mental health treatment.
- Trial name
- T2C (NCT04560075)
- Testing
- Text2Connect, Psychoeducational Videos (PE) Only
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of Pittsburgh
Reduction in Mental Health and Suicide Are the Focus of Interest, Four Assessment Time Points Would be Used to Monitor Participants Through a Laid Down Conditions
Cognitive Resilience Intervention as a Recovery Therapy for Mental Health
The goal of this randomized controlled trial (RCT) is to develop and test a cognitive resilience intervention (CRI) among selected students who are having problems with anxiety, depression, and suicidal thoughts (psychological…
- Trial name
- CRI (NCT06123442)
- Testing
- Cognitive Resilience Intervention
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Depression - Major Depressive Disorder, Suicide
Sustained Ketamine Effectiveness for Suicidal Ideation
As part of the usual clinical activity of the Emergency and Post-Emergency Psychiatric Department, IV ketamine is used to treat suicidal crises in depressed patients hospitalized as an add-on to the treatment of depression.
- Trial name
- SKESI (NCT06806475)
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Montpellier
Depression
Assessing Treatment Emergent Suicidal Ideation in Patients With Major Depression
This study will develop a new methodology to evaluate any treatment-emergent suicidal ideation that might occur when an antidepressant treatment has been started and/or during times when doses are increased in patients with major…
- Trial name
- SAMS (NCT00532103)
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Depression, Suicidal Ideation and Behavior
NRX-101 for Bipolar Depression With Subacute Suicidal Ideation
NMDA antagonist drugs have shown to reduce symptoms of depression and suicidal ideation. NeuroRx has developed NRX-101 (fixed dose combination of D-cycloserine and lurasidone) for oral use in the treatment of bipolar depression…
- Trial name
- NCT03395392
- Testing
- NRX-101, Lurasidone HCl
- Where
- 14 sites in United States
- Volunteers
- 74 people
- Sponsor
- NeuroRx, Inc.
Suicidal, Suicidal Ideation
Intramuscular Ketamine for Suicidal Patients in the Evanston Hospital Emergency Department for Suicidal Distress
This pilot study aims to evaluate the feasibility and acceptability of administering intramuscular ketamine for the acute reduction of suicidal distress during psychiatric boarding at the Evanston Hospital ED.
- Conditions
- Suicidal, Suicidal Ideation, Suicidal Ideation and Behavior, Depression / Major Depressive Disorder
- Trial name
- KEDS-C (NCT07810023)
- Testing
- Ketamine (0.5 mg/kg)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Endeavor Health
Affect, Wellness, Psychological
The Effects of Walking in Nature (vs. an Urban Setting) on the Wellbeing of Postsecondary Students.
The goal of this randomized controlled trial is to examine the effects of a walking intervention (3 walks per week for a period of 4 weeks) in a nature vs. urban setting on the wellbeing of young adult postsecondary students.
- Conditions
- Affect, Wellness, Psychological, Depressive Symptoms, Anxiety Disorders and Symptoms
- Trial name
- NCT05889078
- Testing
- A 4-week walking intervention
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- McGill University