Clinical trials: Suicidal Ideas
Suicidal Ideas, Suicidal Ideation
Couple-Based Crisis Safety Planning
Suicide is a leading cause of death in Veterans. Suicide rates among Veterans have increased approximately 36% from 2001 to 2020.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Crisis; Emotional, Suicide Attempts
- Trial name
- CRP-C (NCT07012824)
- Testing
- Crisis Response Planning, Couples-based Crisis Response Planning
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Suicidal Ideas
Effects of Alcohol and Mood on Attention
Acute use of alcohol is related to increased risk for suicide. However, our understanding of this problem is hindered by the lack of experimental tests of conditions underlying the alcohol use-suicide relationship.
- Trial name
- NCT04276779
- Testing
- Alcohol administration, Positive mood induction, Negative mood induction
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Suicidal Ideas
Improving Care Provided to Patients Treated in a Level 1 Trauma Center Post-suicide Attempt
The aim of the study is to refine, elaborate, and pilot a brief intervention for adult patients following a suicide attempt provided during hospitalization in an acute medical setting.
- Trial name
- NCT01355848
- Testing
- Brief Intervention for Suicidality
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Major Depressive Disorders
Loneliness and Occurrence of Suicide Attempts and Suicidal Ideas
Suicide is a major health problem that causes annually a million death worldwide. Loneliness is known to be associated with suicidal ideation in minors and to be related with suicidal risk in elderly people.
- Trial name
- SOLSTIS (NCT02829671)
- Testing
- Clinical and biological assessment
- Volunteers
- 600 people
- Sponsor
- University Hospital, Montpellier
Bipolar Depression, Suicidal Ideas
Sequential Therapy for the Treatment of Severe Bipolar Depression.
NeuroRx is developing NRX-101, a fixed-dose combination oral capsule composed of d-cycloserine (DCS) and lurasidone for the maintenance of remission from Severe Bipolar Depression with Acute Suicidal Ideation (C-SSRS level 4 or…
- Conditions
- Bipolar Depression, Suicidal Ideas, Suicidal Ideation, Suicide, Attempted
- Trial name
- STABIL-B (NCT02974010)
- Testing
- NRX-101 Oral Capsule, Lurasidone Oral Capsule, Ketamine Intravenous Infusion
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- NeuroRx, Inc.
Suicidal Ideas, Suicidal Ideation
Exploratory Analysis of Interpersonal and Intrapersonal Psychological Processes Implied in Risk-taking and Suicidal Behaviors, in Adult and Adolescent At-risk
In a recent report, Santé Publique France (2023), reported that 4.2% of 18-85 year-olds had thought about suicide in the last 12 months, and 6.8% had attempted suicide in their lifetime and 0.5% in the last year.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Risk-taking
- Trial name
- RISKY (NCT06921226)
- Testing
- Psychological Processes, Risk-taking variables, Suicidal ideation and behavior
- Where
- 3 sites in France
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Suicidal Ideation, Major Depressive Episode
Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode
This study aims at investigating if adjunctive buprenorphine at low dose to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode, and at determining the most effective dose.
- Trial name
- BUPRIS (NCT03646058)
- Testing
- Buprenorphine
- Where
- 9 sites in France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Depressive Disorder, Suicidal Ideas
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Evaluate the efficacy and safety of subcutaneous ketamine added to usual treatment in the management of depressive episodes with suicidal ideation or behavior in adolescent patients, compared to usual treatment added to placebo…
- Trial name
- NCT06957704
- Testing
- ketamine, Midazolam
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Suicidal Ideation, Suicidal Ideas
Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation
Approximately 20% of Canadian adolescents experience thoughts of suicide, or suicidal ideation (SI), and suicide is the second leading cause of death among Canadians aged 15-19 years.
- Trial name
- KSI (NCT06366334)
- Testing
- Ketamine Hydrochloride, Normal saline
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Eastern Ontario
Major Depressive Disorder, Suicidal Ideas
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future.
- Conditions
- Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD
- Trial name
- NCT05437588
- Testing
- Genetic testing
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Suicide
Impairment of the Cognitive Flow in the Development of a Depressive Disorder and Suicidal Ideas
The study consists in estimating the mental load (cognitive saturation) and the production of driving cognition to suicidal patients.
- Trial name
- AQUARIUM (NCT03674580)
- Testing
- Follow-up of the suicidal patients
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Hôpital NOVO