Clinical trials: Suicidal Ideation
Suicidal Ideation
Peer Mentorship to Reduce Suicide Attempts Among High-Risk Adults
This is a single-blind, randomized controlled trial to test the effectiveness of a peer mentorship intervention (PREVAIL) for reducing suicide risk compared to enhanced usual care among participants (N=455) at high-risk for…
- Trial name
- PREVAIL (NCT03373916)
- Testing
- Peer mentorship, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 455 people
- Sponsor
- University of Michigan
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Active Suicidal Ideations
Study to Prevent Negative Thoughts of Life
The purpose of the study is to test whether cognitive behaviour therapy (CBT) offered by trained therapists, to people with current active suicidal ideations, is efficacious as a secondary prevention strategy in Sri Lanka, when…
- Trial name
- NCT00862732
- Testing
- Cognitive behavioural therapy, Treatment as usual
- Where
- Sri Lanka
- Volunteers
- 68 people
- Sponsor
- Institute for Research & Development Sri Lanka
Suicide Ideation, Suicidal Behaviors
A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior
This study will test a model of providing treatment to Latinx/Hispanic youth, who experience suicidal thoughts and behavior, and their caregivers.
- Conditions
- Suicide Ideation, Suicidal Behaviors, Depressive Symptoms
- Trial name
- NCT06882798
- Testing
- Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), SCBT-SB + CHW
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Bradley Hospital
Major Depressive Disorder, Suicide
Pain, Reward, Attention and Neurocircuitry: Biomarkers of Suicidality
The ultimate aim of this study is to identify a biomarker of suicide risk in MDD by measuring the "hedonic spectrum" (pain and reward responsivity), attention and its associated brain structures using brain scans (fMRI and DTI)…
- Conditions
- Major Depressive Disorder, Suicide, Suicidal Ideation
- Trial name
- NCT02811198
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Stigma, Social, Help-Seeking Behavior
Personalized Normative Feedback for Stigma and Help-seeking
People tend to care about what others think and often change our behaviors accordingly. But what if people do not have an accurate understanding of what others really think? Stigma is pervasive, especially in the Black and Asian…
- Trial name
- NCT07683819
- Testing
- Personalized Normative Feedback (PNF), Attention control
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Han Oh
Chronic Pain, Suicidal Ideation
Mindfulness for Pain and Suicide
The proposed study will assess the feasibility and acceptability of a mindfulness-based intervention to reduce functional impairment from chronic pain and risk of suicide.
- Conditions
- Chronic Pain, Suicidal Ideation, Suicide, Attempted, Opioid Use
- Trial name
- NCT05286112
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT), Health Education
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Canandaigua VA Medical Center
Suicidal Ideation, Suicide, Attempted
Aftercare Focus Study (AFS): A Clinical Trial to Reduce Short-Term Suicide Risk After Hospitalization
Increasingly, the period after hospital admission is acknowledged as one of extremely high risk for suicidal patients. While it might be hoped that hospitalization would address and resolve suicide risk, a review of international…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Distress, Psychological, Quality of Life
- Trial name
- NCT04693845
- Testing
- Collaborative Assessment and Management of Suicidality, Treatment as Usual
- Volunteers
- 150 people
- Sponsor
- University of Washington
Depression, Suicidal Ideation
Text2Connect, Component 2 of iCHART (Integrated Care to Help At-Risk Teens)
This study proposes to develop and examine a personalized, text-based intervention designed to improve engagement with mental health (MH) treatment.
- Trial name
- T2C (NCT03982043)
- Testing
- Text2Connect
- Where
- 4 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Pittsburgh
Substance Use, Depression
Trial of Automated Risk Appraisal for Adolescents
This is a study to find out which type of computer screening and nursing support can improve screening for high risk behaviors in doctor's offices.
- Conditions
- Substance Use, Depression, Suicidal Ideation, Risk Behavior
- Trial name
- TARAA (NCT00505440)
- Testing
- Telephone case management and motivational interviewing, Usual care
- Where
- United States
- Volunteers
- 1,185 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Self-injury, Suicidal Ideation and Behavior
Pilot Trial of an Emotion Regulation and Executive Functioning Intervention for Self-Injurious Thoughts and Behaviors (SITBs) in Children
The goal of this study is to develop and test an outpatient intervention for preadolescents (ages 7-12) with self-injurious thoughts and behaviors (SITBs). The main questions it aims to answer are: 1.
- Conditions
- Self-injury, Suicidal Ideation and Behavior, Executive Functioning, Emotion Regulation
- Trial name
- NCT07281365
- Testing
- Treatment as usual (TAU), Preadolescent SITB Intervention
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Colorado, Denver
Mental Health, HIV
"Gwan Enjoy Life:" A Peer-Supported Mental Health Mentoring Intervention to Improve Engagement in Care Among Sexual Minority Men Living With HIV in Jamaica
Sexual minority men (SMM) in Jamaica face many challenges that affect their health and well-being. Although they make up a relatively small part of the population, they are much more likely to be living with HIV than the general…
- Conditions
- Mental Health, HIV, Pyschological Distress, Suicidal Ideation
- Trial name
- GwanEnjoyLife (NCT07762612)
- Testing
- Gwan Enjoy Life Interveniton
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Self Harm, Depression
Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth
This study is designed to refine and test the efficacy of a computer assisted culturally informed and flexible/adaptive intervention for Latino adolescents for whom self-harm behaviors are a health disparity-specifically, Latinas…
- Conditions
- Self Harm, Depression, Emotion Dysregulation, Suicidal Ideation
- Trial name
- NCT03709472
- Testing
- Computer Assisted CIFFTA, Behavioral: Traditional face-to-face treatment-no technology
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Miami
Bipolar Depression, Suicidal Ideation
NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression
NMDA antagonist drugs have increasingly been demonstrated to reduce symptoms of depression and suicidal ideation. NeuroRx has developed a sequential therapy consisting of IV NRX-100 (ketamine HCL) for rapid stabilization of…
- Trial name
- SevereBD (NCT03396601)
- Testing
- Ketamine Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- NeuroRx, Inc.
Smoking Cessation
Assessing Neuropsychiatric Symptoms Including Depression, Anxiety, Irritability, and Suicidal Thoughts or Behavior in Subjects Quitting Smoking on Varenicline Tartrate or Placebo
Study objective is to compare neuropsychiatric adverse events in subjects treated with varenicline or placebo in a controlled setting where both groups are experiencing nicotine withdrawal.
- Trial name
- NCT00749944
- Testing
- varenicline
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Pfizer
Depression, Anxiety
Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health
This project aims to enhance AN university students' behavioral health by supporting their cultural identity development. While the connection between cultural identity and behavioral health is becoming clearer, comparably less…
- Conditions
- Depression, Anxiety, Suicidal Ideation, Substance Use
- Trial name
- NCT04561544
- Testing
- Knowing Who You Are (Becoming): Cultural Identity Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Suicidal Ideation, Suicide Attempt
Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for young adults (ages 18-27) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- RISE (NCT07051200)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Substance Dependence
Efficacy of Cognitive Bias Modification in Residential Treatment for Addiction
The purpose of this study is to determine whether computer bias modification for interpretation bias (CBM-I) is effective in the reduction of suicidal ideation in substance use disorders.
- Trial name
- NCT03000699
- Testing
- Cognitive Bias Modification
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Centre for Addiction and Mental Health
Suicidal Ideation, Depression
Social Connections and Healthy Aging (The Senior Connection)
This randomized trial compares peer companionship to care-as-usual in primary care on the outcome of risk for suicidal behavior in late life.
- Trial name
- TSC (NCT01408654)
- Testing
- Peer Companionship
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- University of Rochester
Suicide and Depression
Accelerated Theta Burst Stimulation for Treatment of Suicidality in Depressed Patients
The objective of this study is to investigate efficacy of accelerated theta burst stimulation (TBS) in suicidal reduction in patients with unipolar and bipolar depression
- Trial name
- NCT06289842
- Testing
- Transcranial Magnetic Stimulation MagPro R30 with the MCF-B70 figure-of-eight coil (MagVenture, Denmark)
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Zagazig University