Clinical trials: Suicidal Ideation and Behavior
Suicide and Self-harm, Suicide
Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Open Trial
The primary aim of the present study is leverage existing infrastructure to develop novel technological features for a novel personalized smartphone intervention system, called the Mobile Application to Prevent Suicide (MAPS)…
- Conditions
- Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05180383
- Testing
- Mobile Application to Prevent Suicide (MAPS)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Butler Hospital
Depression, Anxiety, Suicidal Ideation
A Trauma-Informed Approach for Positive Youth Development for Montana Students
Given the prevalence of suicide and mental health issues in rural Montana, this project is intended to help mitigate stressors that may contribute to poor behavioral and mental health in high school-aged children.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Stress, Trauma
- Trial name
- NCT04664855
- Testing
- Trauma-Informed Yoga
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Montana State University
Suicide
CAMS Relational Agent System (CAMS-RAS) for Suicide Prevention
This Phase II study is a continuation of the Phase I feasibility study where the investigators fully met and exceeded project aims to design, build, and test the usability and acceptability of an avatar-based system, Jaspr Health…
- Trial name
- V-CAMS (NCT03584386)
- Testing
- Jaspr, Jaspr-at-Home (JAH)
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Suicidal Ideation, Suicide, Attempted
Improving Treatment Outcomes for Suicidal Veterans With PTSD
The efficacy of cognitive processing therapy (CPT) for reducing the symptoms of posttraumatic stress disorder (PTSD) across populations including military personnel and veterans is well supported.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Ptsd
- Trial name
- NCT04690582
- Testing
- Cognitive Processing Therapy (CPT), Crisis Response Plan (CRP), Safety Planning Intervention (SPI)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Ohio State University
Major Depressive Disorder, Anxiety Disorder
Ketamine Infusion for Adolescent Depression and Anxiety
The purpose of this study is to determine the tolerability and short-term efficacy of a single ketamine infusion for the treatment of adolescents with 1) medication-refractory major depressive disorder (MDD) and/or 2)…
- Trial name
- NCT02579928
- Testing
- Ketamine, Midazolam
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Yale University
Depression, Unipolar Depression
Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression
This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for depression.
- Conditions
- Depression, Unipolar Depression, Treatment Resistant Depression
- Trial name
- CREST-MST (NCT03191058)
- Testing
- Magnetic Seizure Therapy, Electroconvulsive Therapy
- Where
- 3 sites in United States, Canada
- Volunteers
- 239 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Suicidal Ideation
Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools
Completing evidence-based treatments for depression has been shown to be particularly problematic for Black adolescents. If Black adolescents' depression treatment needs are to be met, the engagement challenges and the factors…
- Trial name
- NCT03940508
- Testing
- Making Connections Intervention, IPT-A
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York University
Suicide
Patient and Provider Outcomes of E-Learning Training in Collaborative Assessment and Management of Suicidality
Suicide prevention among military Veterans has become a national priority; yet, there is a gap in suicide-specific intervention training for mental health students and professionals.
- Trial name
- CAMS (NCT00905827)
- Testing
- CAMS
- Where
- 5 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
The overarching goal of this UH2-UH3 proposal is to work with the NIH Health Care Systems Research Collaboratory to develop and implement a large scale, cluster randomized pragmatic clinical trial demonstration project that…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02655354)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management
- Where
- 24 sites in United States
- Volunteers
- 635 people
- Sponsor
- University of Washington
Suicide, Attempted, Suicidal Ideation
Mobile Technology for Reducing and Preventing Adolescent Suicide
This single-group open-label trial will evaluate the feasibility and preliminary efficacy of a suicide prevention mobile application when used as an adjunct to usual care in adolescents.
- Trial name
- NCT04896593
- Testing
- Smartphone App
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Hartford Hospital
Suicidal Ideation
Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation
This is a randomized, double-blind, placebo-controlled study of the investigational drug uridine as a treatment for suicidal ideation in veterans.
- Trial name
- NCT03265964
- Testing
- Uridine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Office of Research and Development
Depression
Improving Mood in Veterans in Primary Care
The purpose of the Improving Mood in Veterans in Primary Care (IIR 14-047) is to evaluate a brief educational individual workshop that is meant to help Veterans better understand feelings of sadness and ways to improve their…
- Trial name
- NCT02276807
- Testing
- Brief Behavioral Activation, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- VA Office of Research and Development
Transgender, Depression
Mental Health Support for Transgender and Gender-expansive Individuals
This study will evaluate an intervention's feasibility, acceptability and efficacy potential in a one-arm trial with Romanian transgender and gender diverse (e.g., gender non-binary) (TGD) individuals who report depression or…
- Conditions
- Transgender, Depression, Anxiety, Suicidality
- Trial name
- NCT06229132
- Testing
- LGBTQ-affirmative CBT for transgender individuals
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Columbia University
Major Depressive Disorder, Suicidal Ideation
Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation
The study aims to use a combined clinical and translational approach to identify an efficient pharmacotherapy for the acute management of suicidality and the epigenetic regulation associated with the treatment.The primary…
- Trial name
- AFSP (NCT01134731)
- Testing
- paliperidone, lithium
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Alabama at Birmingham
Suicidal Ideation, Suicide, Attempted
Reducing Suicide Ideation Among Young People
It is Cluster Randomized Control Trial research to examine feasibility and relevance of the modified tool Nae Disha for Life, which will incorporate suicide prevention and resilience to reduce suicide ideation among young people…
- Trial name
- NCT06474312
- Testing
- Nae Disha
- Where
- India
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anxiety, Depression
Sexual and Gender Minority Youth (SGMY) and Online Interventions to Increase Help-seeking for Anxiety and/or Depression
the investigators will use 4 technology based tools (combinations of youtube videos, links to online resources, tiktok videos, and other media) in a study of 96 Sexual and Gender Minority Youth (SGMY) to determine the…
- Conditions
- Anxiety, Depression, Adolescent Behavior, Sexual and Gender Minorities
- Trial name
- NCT06083987
- Testing
- Intersectionality and Identity, Confidentiality, Educating Your Community
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression, Suicidal Ideation
BRITEPath- Phase 2
BRITEPath (BP) aims to support co-located mental health clinicians in the development of a high quality, effective, and personalized safety plan for referred patients who screen positive for depression and/or suicidal ideation.
- Trial name
- NCT04672798
- Testing
- BRITEPath, Treatment As Usual (TAU)
- Where
- 6 sites in United States
- Volunteers
- 101 people
- Sponsor
- University of Pittsburgh
Suicide, Depression
Engaging Suicidal Patients in Mental Health Treatment
The investigators will identify characteristics of suicidal patients who do or do not attend a first mental health visit following referral using administrative data.
- Conditions
- Suicide, Depression, Mental Health Impairment, Suicidal Ideation
- Trial name
- NCT05021224
- Testing
- Caring Contacts, Reminders, Informational Poster
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Suicidal Ideation, Suicide, Attempted
The Acceptability and Feasibility of an ED-based, Peer-delivered, Suicide Safety Planning Intervention
Safety planning is a brief, ED-feasible intervention which has been demonstrated to save lives, and has been universally recommended by every recent expert consensus panel on suicide prevention strategies.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Mental Health Issue
- Trial name
- NCT04068142
- Testing
- Peer Supporter Safety Planning
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Arkansas
Depression, Suicidal Ideation
Social Connections and Late Life Suicide
With the long-term goal of improving interventions for late-life suicide, the purpose of this study is to examine whether a mechanism by which behavioral interventions reduce risk for late-life suicide is by increasing social…
- Trial name
- NCT02188485
- Testing
- ENGAGE
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Rochester