Clinical trials: Suicidal Ideation and Behaviors
Insomnia, Depression
Reducing Suicidal Ideation Through Insomnia Treatment
Epidemiologic reports have linked insomnia to suicidal ideation and suicide death. However, no studies have determined whether treating insomnia decreases the risk of suicidality.
- Conditions
- Insomnia, Depression, Suicidal Ideation
- Trial name
- REST-IT (NCT01689909)
- Testing
- Zolpidem-CR
- Where
- 4 sites in United States
- Volunteers
- 103 people
- Sponsor
- Augusta University
Bipolar Disorder, Suicidal Ideation
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
This study aims to use a retrospective cohort approach to explore the impact of lithium carbonate on suicide and self-harm related events among adolescents and young adults with bipolar disorder in China.The primary objective of…
- Conditions
- Bipolar Disorder, Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self Injury
- Trial name
- NCT06424613
- Testing
- Lithium Carbonate, Non-lithium medication
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Adverse Mental/Physical Effects of Low Dose S. Tortuosum.
Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals
Phosphodiesterase is a candidate for the Rx \& prevention of cognitive and psychotic disorders. Since caffeine targets primarily PDE4(Phosphodiesterase subtype 4), caffeine analogs have been developed to mimic the actions of…
- Trial name
- NCT01805518
- Testing
- Scelectium Tortuosum
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Woodbury, Michel, M.D.
Domestic Violence, Post-Traumatic Stress Disorder
Mental Health Symptoms and Intimate Partner Violence
Using a touch screen computer, the researchers are screening emergency department patients for intimate partner violence and mental health issues.
- Conditions
- Domestic Violence, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT00166075
- Testing
- Computer screen with community resource printout
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Emory University
Suicidal Thoughts and Behaviors, Social Connectedness
Social Threat, Adolescent Relationships, and Suicidality Study
In recent years, adolescents are having higher rates of emotional health problems, such as suicidal thoughts and behaviors (STBs).
- Conditions
- Suicidal Thoughts and Behaviors, Social Connectedness, Responses to Social Threat
- Trial name
- STARS (NCT07294079)
- Testing
- Social threat
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Domestic Violence, Psychological Distress
GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda
The goal of this community-based interventional study was to determine the effectiveness of the 'Trauma Resilience \& Understanding Self-help Therapy' (TRUST) in managing domestic violence \& primary trauma among formerly…
- Conditions
- Domestic Violence, Psychological Distress, Post-Traumatic Stress Disorder, Suicidality
- Trial name
- GBV (NCT06073964)
- Testing
- Trauma Resilience & Understanding Self-help Therapy
- Where
- Uganda
- Volunteers
- 284 people
- Sponsor
- Kampala International University
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Suicide, Suicide, Attempted
Implementability and Effectiveness of the Safety Planning Intervention for Suicidal Behavior
The Safety Plan Intervention (SPI) has demonstrated to reduce suicide reattempts and to increase the ambulatory follow-up in american war veterans.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT04230434
- Testing
- Safety Plan Intervention
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Psychosis, Suicide Prevention
Cognitive AppRoaches to coMbatting Suicidality
This is a randomised controlled trial which investigates the effectiveness of CARMS (Cognitive AppRoaches to coMbatting Suicidality) therapy in reducing suicidal thoughts and how well CARMS works in practice within the NHS.
- Conditions
- Psychosis, Suicide Prevention, Suicidality
- Trial name
- CARMS (NCT03114917)
- Testing
- Cognitive AppRoaches to coMbatting Suicidality (CARMS)
- Where
- 4 sites in United Kingdom
- Volunteers
- 329 people
- Sponsor
- University of Manchester
Suicidal Ideation
Ask Suicide-Screening Questions (ASQ) for Youth With Autism Spectrum and Neurodevelopmental Disorders
Background: Suicide is the second leading cause of death for young people ages 10-24 years. There is no gold standard for evaluating suicidal thoughts and behaviors in young people with autism spectrum disorder (ASD) or other…
- Trial name
- NCT04317118
- Where
- 3 sites in United States
- Volunteers
- 278 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depressive Episode, Posttraumatic Stress Disorder
Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation
The purpose of this study is to determine whether transcranial magnetic stimulation (TMS) is effective in the treatment of suicidal thinking in individuals with a depressive episode and either posttraumatic stress disorder…
- Conditions
- Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
- Trial name
- NCT01212848
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Depressive Disorder, Major, Generalized Anxiety Disorder
Student Precarity and Psychiatry
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and…
- Conditions
- Depressive Disorder, Major, Generalized Anxiety Disorder, Suicidal Ideation, Loneliness
- Trial name
- PEPSY (NCT07618208)
- Testing
- Questionnaires
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depressive Disorder, Major, Suicidal
A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide
The purpose of the study is to evaluate the efficacy, safety, and tolerability of SLS-002 (intranasal racemic ketamine) in addition to standard of care on symptoms of Major Depressive Disorder (MDD) and suicidality, in…
- Trial name
- NCT04669665
- Testing
- SLS-002, Standard of care, Intranasal device
- Where
- 21 sites in United States
- Volunteers
- 164 people
- Sponsor
- Seelos Therapeutics, Inc.
Suicidal Ideation
Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation
This is a randomized, double-blind, placebo-controlled study of the investigational drug uridine as a treatment for suicidal ideation in veterans.
- Trial name
- NCT03265964
- Testing
- Uridine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Teen Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- Teen RISE (NCT07170657)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression
iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment
This is an open label, pilot, feasibility study evaluating effects of Intermittent Theta Burst Transcranial Magnetic Stimulation (iTBS) on 5 eligible adolescents for the treatment of depression.
- Trial name
- NCT04485455
- Testing
- iTBS Device/Motor Threshold Coil, iTBS Device/Treatment Coil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Suicide Ideation, Suicidal Intention
Classification and Assessment of Mental Health Performance Using Schematics
This is an open enrollment study to collect data for the optimization of smartphone-based algorithms for the early detection of mental health and suicidal risk in a student population.
- Conditions
- Suicide Ideation, Suicidal Intention, Suicide and Depression
- Trial name
- CAMPUS (NCT04275908)
- Testing
- MHSAFE app
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clarigent Health
Depression, Suicide
Intranasal Ketamine for Late-Life Depression and Suicidal Ideation
The investigators of this study plan to investigate the feasibility and efficacy of repeated doses of intranasal ketamine in severely depressed patients who are at least 65 years of age and experiencing suicidal ideation.
- Conditions
- Depression, Suicide, Suicidal Ideation
- Trial name
- NCT02295787
- Testing
- Ketamine
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation, Suicide Attempt
Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for young adults (ages 18-27) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- RISE (NCT07051200)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Covid19, Mental Health Disorder
MIND/COVID-19: Mental Health Impact and NeeDs Associated With COVID-19: a Comprehensive National Evaluation in Spain
The aim of the proposed project is to provide a comprehensive assessment of the mental health impact of the ongoing COVID-19 outbreak in Spain.
- Conditions
- Covid19, Mental Health Disorder, Mental Health Conditions
- Trial name
- NCT04556565
- Where
- 18 sites in Spain
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Jordi Alonso