Clinical trials: Suicidal and Self-Injurious Behavior
Self-Harm, Deliberate, Borderline Personality Disorder
Dialectical Behavior Therapy vs Enhanced Usual Care for Suicidal and Self-harming Adolescents. 10 Year Follow-up
The purpose of the study is to evaluate the long-term efficacy of dialectical behavior therapy (DBT) in treatment of adolescents with deliberate self harm compared to enhanced usual care (EUC).
- Trial name
- NCT04298190
- Testing
- Dialectical Behaviour Therapy for Adolescents (DBT-A), Enhanced usual care
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Oslo University Hospital
Suicide Attempts, Suicidal Ideation
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.
- Conditions
- Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
- Trial name
- ASSIST (NCT05078970)
- Testing
- Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Cyberbullying, Depression
Building Resilience in Cyberbullying Victims
This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims.
- Conditions
- Cyberbullying, Depression, Non Suicidal Self Injury, Social Anxiety
- Trial name
- Resilience (NCT04509531)
- Testing
- Wise Intervention (SA, ITP and resilience), Standard preventive intervention
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Suicidal Ideation
Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation
Background. Suicidal ideation and depressive symptoms are highly prevalent among adolescents, with suicide representing a leading cause of death in this age group worldwide.
- Trial name
- NCT07063914
- Testing
- Reframe-IT and CARIBOU
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de los Andes, Chile
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Military Transition, Community Reintegration
Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans
The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life.
- Conditions
- Military Transition, Community Reintegration, Mental Health, Suicidal Ideation
- Trial name
- NCT06778278
- Testing
- Transition Health and Resilience through Valued Experiences (THRiVE) Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- RTI International
Suicidal Ideation, Major Depressive Disorder
Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy
This protocol proposes an initial randomized clinical trial that includes all patients with suicidal ideation (SI) at baseline, and with SI as the primary outcome measure to examine whether Right Unilateral Low-Amplitude Pulse …
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- LAP-ST vs ECT (NCT06529029)
- Testing
- Sigma-Stim, RUL LAP-ST (Low-Amplitude Pulse Seizure Therapy - Right Unilateral)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Sleep Disorder, Mental Health Issue
Improving Sleep in a Psychiatric Hospital
The purpose of this study is to examine effects of sleep promotion versus treatment as usual (TAU) on subjective, self-reported sleep while in inpatient psychiatric treatment, to examine effects of sleep promotion vs.
- Trial name
- NCT07010718
- Testing
- Scented Oil, Ear Plugs, Eye Mask
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation and Behaviors, Suicide Attempt
Enhanced Brief CBT for Suicidal Inpatients With Mood Disorders
The goal of this clinical trial is to evaluate whether enhanced brief cognitive behavioral therapy (E-BCBT) can help reduce suicidal thoughts and behaviors among psychiatric inpatients.
- Conditions
- Suicidal Ideation and Behaviors, Suicide Attempt, Cognitive Behavioral Therapy
- Trial name
- E-BCBT (NCT07072845)
- Testing
- Enhanced Brief Cognitive Behavioral Therapy (E-BCBT) for Suicidal Inpatients, Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Hyung Keun Park
Suicide Prevention
Feasibility Study of a Combined Intervention for Suicidal Inpatients in Psychiatric Crisis Units.
Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap . Hospitalization offers a crucial opportunity for life-preserving intervention .
- Trial name
- HOPAIR (NCT07119671)
- Testing
- HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hôpital le Vinatier
Mental Disorders, Suicide, Attempted
Ideation Trajectories and Suicide Attempts in Adolescents With Psychiatric Disorders in Chile
This project seeks to evaluate the trajectories of suicidal ideation and attempts in adolescent patients with psychiatric disorders in secondary care controls in the Maule region, in relation to clinical factors (depressive…
- Trial name
- NCT04635163
- Testing
- None intervention
- Where
- Chile
- Volunteers
- 388 people
- Sponsor
- Universidad Católica del Maule
Bipolar Disorder, Bipolar Depression
Efficacy of Convulsive Therapies for Bipolar Depression
This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for Bipolar Disorder (BD).
- Conditions
- Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- CORRECT-BD (NCT03641300)
- Testing
- Magnetic Seizure Therapy (MST), Electroconvulsive Therapy (ECT)
- Where
- 3 sites in Canada
- Volunteers
- 76 people
- Sponsor
- Centre for Addiction and Mental Health
Mechanistic Self-Dehumanization Condition, Control Condition
Inducing Self-Dehumanization to Examine Oxytocin and Suicide Risk
The goal of this experiment is to further determine if self-dehumanization is a novel risk factor for suicide. This study will induce self-dehumanization using a novel experimental self-dehumanized future condition (i.e., a…
- Trial name
- NCT06710964
- Testing
- The Ten Item Personality Inventory, Mechanistic Self-Dehumanization Condition, Debrief
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida State University
Suicide Attempt
Evaluation of the Risk Associated With Impulsivity and Other Neuropsychological Factors on Suicidal Relapse Within Hospital Emergencies
Suicidal behavior (SB) is a major public health problem in France, with over 10,000 suicides (6th in the EU28) and 220,000 suicide attempts (SA) per year. These data seem underestimated by 20%.
- Trial name
- SUI-PREDICT (NCT03026387)
- Testing
- Neuropsychological battery tests
- Where
- France
- Volunteers
- 650 people
- Sponsor
- University Hospital, Montpellier
Major Depressive Disorder, Bipolar Depression
Chronotherapy Randomized Controlled Trial
Chronotherapy is a term that describes therapeutic alterations of sleep wake cycles. Different variations of sleep deprivation, set sleep wake schedules, and types of light therapy have demonstrated efficacy in rapidly treating…
- Conditions
- Major Depressive Disorder, Bipolar Depression, Suicidal Ideation
- Trial name
- NCT02176824
- Testing
- Total Sleep deprivation, Sleep Phase Advance, and Bright Light Therapy, Partial Sleep deprivation, Sleep Phase Delay, and Low amber light., Treatment as usual
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Medical University of South Carolina
Suicide, Attempted, Suicidal Ideation
Developing and Implementing an Adolescent Suicide Prevention Program in a Community Mental Health Setting
This is a three phase study to develop and implement an adolescent suicide prevention program in a community mental health setting.
- Trial name
- NCT03992391
- Testing
- Suicide Prevention Intensive Outpatient Program
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicidal and Self-injurious Behaviour
Collaborative Adolescent Research on Emotions and Suicide
Suicide is the third leading cause of death among adolescents in the US yet there is a paucity of research on effective treatments for this population.
- Trial name
- CARES (NCT01528020)
- Testing
- Dialectical Behavior Therapy, Individual and Group Supportive Therapy
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- University of Washington
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Unipolar Depression, Impulsive Behavior
How to Reduce Suicidal Thoughts and Impulsivity in Depression
The study aims at investigating if tDCS applied to left DLPFC or to right OFC to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode.
- Conditions
- Unipolar Depression, Impulsive Behavior, Suicidal Ideation
- Trial name
- DEPIMPULSE (NCT05894980)
- Testing
- active tDCS stimulating left DLPFC, active tDCS stimulating right OFC
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon