Clinical trials: Suicide; Trauma
Domestic Violence, Psychological Distress
GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda
The goal of this community-based interventional study was to determine the effectiveness of the 'Trauma Resilience \& Understanding Self-help Therapy' (TRUST) in managing domestic violence \& primary trauma among formerly…
- Conditions
- Domestic Violence, Psychological Distress, Post-Traumatic Stress Disorder, Suicidality
- Trial name
- GBV (NCT06073964)
- Testing
- Trauma Resilience & Understanding Self-help Therapy
- Where
- Uganda
- Volunteers
- 284 people
- Sponsor
- Kampala International University
Post-Traumatic Stress Disorders, Stress Disorders
Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings
The purpose of this study is to evaluate Cognitive-behavioral therapy (CBT) for deployment-related post-traumatic stress disorder (PTSD) that can be used by behavioral health consultants working with Service Members in the…
- Conditions
- Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
- Trial name
- NCT00974402
- Testing
- Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
PTSD, Post Traumatic Stress Disorder
Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery
The overall strategy is to recruit veterans with PTSD who report minimal current cannabis use but are interested in or considering therapeutic cannabis to manage mental health symptoms (anxiety, depression, PTSD and/or…
- Conditions
- PTSD, Post Traumatic Stress Disorder, Suicide, Cannabis Use
- Trial name
- CAPER (NCT06222268)
- Testing
- Cannabidiol (CBD) only, Delta-9-tetrahydrocannabinol (THC) only, THC:CBD 1:1
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Leslie Lundahl
Insomnia, Suicidal Ideation
RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts
There is a strong association between insomnia and suicidal thoughts and behaviors. Insomnia also frequently co-occurs with other common conditions associated with suicide such as depression and posttraumatic stress disorder.
- Trial name
- NCT03603717
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
- Where
- 3 sites in United States
- Volunteers
- 283 people
- Sponsor
- VA Office of Research and Development
Prolonged Grief Disorder, Suicidality
Prolonged Grief and Suicide Among Veterans
The primary research question in this study will ask, among those receiving outpatient mental health services (MHS) at the Eastern Colorado Healthcare System (ECHCS)/Denver Veterans Affairs Medical Center (VAMC), how many suffer…
- Trial name
- NCT01247025
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
PTSD, Suicidal Ideation
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD).
- Conditions
- PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
- Trial name
- NCT06285708
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Firearm Injury, Pediatric Emergency Medicine
Randomized Trial to Improve Safe Firearm Storage
The goal of this clinical trial is to test the effect of providing gun locks to caregivers of children presenting to the emergency department for mental health concerns.
- Conditions
- Firearm Injury, Pediatric Emergency Medicine, Suicide and Self-harm, Mental Health Issue
- Trial name
- FARTHER (NCT05568901)
- Testing
- Lethal means counseling, Provision of Cable-style gun locks
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Post Traumatic Stress Disorder PTSD, Suicidal Ideation
Deep TMS for PTSD With Suicidal Ideation
The goal of this clinical trial is to evaluate whether deep transcranial magnetic stimulation (DTMS) using the H1-coil can safely and effectively reduce suicidal ideation in adults diagnosed with post-traumatic stress disorder…
- Trial name
- DTMS-PTSD-SI (NCT07880340)
- Testing
- Deep Transcranial Magnetic Stimulation (DTMS)
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- D.R. Rut Zaks OHAYON
Posttraumatic Stress Disorder, Borderline Personality Disorder
Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD-BPD)
Posttraumatic Stress Disorder (PTSD) with co-occurring Borderline Personality Disorder (BPD) (i.e., PTSD-BPD) is common (as high as 58%), debilitating, costly, and limited treatment options available for this population.
- Trial name
- NCT04230668
- Testing
- Cognitive Processing Therapy with Suicide Risk Management, Treatment as Usual with Suicide Rick Management
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Palo Alto University
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Post Traumatic Stress Disorder, Cannabis Use
Warrior CARE: Cannabis Behavioral Health
This study is a randomized, controlled clinical trial to examine the therapeutic potential of cannabinoids for treating veterans with PTSD and suicidal ideation.
- Conditions
- Post Traumatic Stress Disorder, Cannabis Use, Suicide, Veterans
- Trial name
- CBH (NCT06381180)
- Testing
- Tetrahydrocannabinol, Cannabidiol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Wayne State University
Posttraumatic Stress Disorder (PTSD), Suicidal Ideation
Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD
The purpose of this research is to see if Crisis Response Planning (CRP), a brief strategy designed to help people cope effectively with emotional crises, combined with Cognitive Processing Therapy (CPT), a talk treatment for…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Suicidal Ideation, Suicide Attempt
- Trial name
- mCPT+CRP (NCT07238192)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Ohio State University
Traumatic Brain Injury
Use of a Traumatic Brain Injury (TBI) Screen in a Veteran Mental Health Population
The primary aims of this study are to: 1) Establish the concurrent criterion-related validity of four traumatic brain injury (TBI) screening questions (TBI-4) using the Ohio State University TBI Identification Method (OSU TBI-ID)…
- Trial name
- TBI (NCT01118182)
- Where
- United States
- Volunteers
- 1,810 people
- Sponsor
- VA Eastern Colorado Health Care System
Sleep Disorders, PTSD
Efficacy of a Brief Nightmare Treatment for Veterans
The purpose of this study is to find out what effects Exposure, Rescripting, and Relaxation Therapy (ERRT) has on nightmares and associated problems in veterans.
- Conditions
- Sleep Disorders, PTSD, Suicide
- Trial name
- NCT01220401
- Testing
- exposure, relaxation, and rescription therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Tulsa
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Posttraumatic Stress Disorder, Reintegration
Evaluation of ProVetus/Sponsorship Initiative
Some Veterans who recently served in the military report significant psychological problems based on their experiences in the military.
- Conditions
- Posttraumatic Stress Disorder, Reintegration, Social Support
- Trial name
- NCT02627612
- Testing
- Pro Vetus, Team Red, White, and Blue (TM RWB)
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Post Traumatic Stress Disorder, Cannabis Use
Warrior CARE: Naturalistic Observation and Harm Reduction
This study is looking at therapeutic potential of reducing Tetrahydrocannabinol (THC) levels in regular cannabis smokers using contingency management (CM) intervention in a U.S.
- Conditions
- Post Traumatic Stress Disorder, Cannabis Use, Suicide
- Trial name
- NOC (NCT05386862)
- Testing
- Reduce THC Use
- Where
- United States
- Sponsor
- Wayne State University
Suicidal Ideation
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a study group of 150 civilian and Veteran participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Trial name
- PRE-EMPT (NCT07484906)
- Testing
- fMRI Neurofeedback, Accelerated theta burst stimulation, Psilocybin assisted therapy
- Sponsor
- University of New Mexico
Non-Suicidal Self Injury, Suicide
Dialectical Behavioral Therapy in Juvenile Justice
Self-injurious thoughts and behaviors (SITBs) are a serious public health concern, particularly for youth involved in the juvenile justice system (JJS), which the Georgia State Juvenile Justice System (GAJJS) intends to address…
- Conditions
- Non-Suicidal Self Injury, Suicide, Self-harm, Emotion Regulation
- Trial name
- DBT-A&JJS (NCT05583279)
- Testing
- Dialetical Behavioral Therapy for Adolescents
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Catholic University of America