Clinical trials: Suicide Attempts
Major Depressive Disorder
miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome
The purpose of this study is to examine whether neural-derived exosomal miRNAs are differentially expressed that are specific to suicidal ideation or behavior, and which by affecting specific miRNA targets and pathways, are…
- Trial name
- NCT02418195
- Testing
- ketamine
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Relatives
Family Connections for Caregivers of People With Suicidal Behavior
The aim of our study is to verify the efficacy of the Family Connections intervention for relatives of people diagnosed with suicidal behavior disorder in a randomized control trial with a Spanish participants.
- Trial name
- NCT05157607
- Testing
- Family Connections Protocol for Relatives of Patients with SBD., Treatment as Usual Optimized Protocol (TAU-O)
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Suicide, Suicidal Ideation
Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago
Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today.
- Conditions
- Suicide, Suicidal Ideation, Suicide Attempt
- Trial name
- SP-BSC (NCT07125144)
- Testing
- Black Youth Suicide Prevention in Chicago, Signs of Suicide: Standard/Existing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Suicide Attempts, Suicidal Ideation
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.
- Conditions
- Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
- Trial name
- ASSIST (NCT05078970)
- Testing
- Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Bereavement
Long-term Consequences of Bereavement in Children, Adolescents and Young Adults
The purpose of this study is to examine how the death of a parent as a child, adolescent or young adult affects health and psychosocial wellbeing in adult life and to evaluate the impact in adult life of counseling to children…
- Trial name
- NCT01453699
- Where
- Denmark
- Volunteers
- 1,225,660 people, healthy volunteers welcome
- Sponsor
- Danish Cancer Society
Suicide, Suicidal Ideation
Phone Call Follow-up After Crisis Centre Presentation With Suicidal Ideation and Behaviours.
This goal of this research is to examine the efficacy and feasibility of starting a phone call follow-up program for individuals discharged to the community after presenting to the Crisis Response Centre (CRC), a standalone…
- Conditions
- Suicide, Suicidal Ideation, Suicide, Attempted, Suicide Gesture
- Trial name
- NCT03444935
- Testing
- Follow-up phone call
- Where
- Canada
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Winnipeg Regional Health Authority
Attempt Suicide
Genetic Variants Associated With Adolescent Suicide Attempts
Suicidal behaviors is known to aggregate in families. The purpose of this study is to evaluate association between common polymorphisms in genes important for neurobiological pathways linked to suicidal behaviors and suicide…
- Trial name
- VGTSA (NCT02001649)
- Testing
- SNP Genotyping
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Suicidal Ideation, Suicide Attempt
Neural Correlates of Suicidal Behavior in Youth
This study, titled "Neural Correlates of Suicidal Behavior in Youth: a Pre and Post CAMS Therapy Neuroimaging Study," aims to better understand the brain mechanisms underlying suicidal thoughts and behaviors in adolescents and…
- Conditions
- Suicidal Ideation, Suicide Attempt, Suicidal Behavior, Depression / Major Depressive Disorder
- Trial name
- NCT07568054
- Testing
- CAMS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Suicidal Ideas, Suicidal Ideation
Couple-Based Crisis Safety Planning
Suicide is a leading cause of death in Veterans. Suicide rates among Veterans have increased approximately 36% from 2001 to 2020.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Crisis; Emotional, Suicide Attempts
- Trial name
- CRP-C (NCT07012824)
- Testing
- Crisis Response Planning, Couples-based Crisis Response Planning
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Suicide and Depression, Psychological Distress
Preventing Psychological Distress and Suicidal Behaviours: a Web-based and Mobile Suicide Prevention Intervention in the General Population
An interventional research study will be undertaken to assess the effectiveness of the promotion at the local level of an e-health tool for suicide and psychological distress prevention (the StopBlues application and website).
- Conditions
- Suicide and Depression, Psychological Distress, Anxiety Disorders, Local Authorities Promotion
- Trial name
- PRINTEMPS (NCT03565562)
- Testing
- Promotion of the e-health tool by local authorities, Promotion of the e-health tool by local authorities and GPs
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Nonsuicidal Self Injury, Self Hatred
Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents
Participants (aged 13-16) will be randomized to: (1) an online, active control group program encouraging feelings disclosure (i.e.
- Conditions
- Nonsuicidal Self Injury, Self Hatred, Suicidal Thoughts, Suicide Attempts
- Trial name
- Project SAVE (NCT04498143)
- Testing
- Project SAVE ("Stop Adolescent Violence Everywhere") SSI, Active Comparator: Supportive Therapy ("Share Your Feelings") SSI
- Where
- United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- University of Denver
Suicidal Ideation and Behavior, Mood Disorders
Videoconference-Based Brief Cognitive Behavioral Therapy for Patients With Mood Disorders at High Risk for Suicide
This study aims to investigate inflammatory biomarkers associated with suicide risk and to evaluate the efficacy of videoconference-based brief cognitive-behavioral therapy (V-BCBT) in patients with mood disorders at high risk…
- Conditions
- Suicidal Ideation and Behavior, Mood Disorders, Suicide Attempt, Cognitive Behavior Therapy
- Trial name
- V-BCBT-BIO (NCT07857291)
- Testing
- Videoconference-Based Brief Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Hyung Keun Park
Self-Harm, Deliberate, Non-Suicidal Self Injury
Aspects of Self-harm - Cognition, Imaging and Treatability
Deliberate self-harm (DSH) is a common symptom in psychiatric disorders. This study aim at increased understanding of parameters associated with DSH with the long term goal to potentially improve and possibly personalise its…
- Conditions
- Self-Harm, Deliberate, Non-Suicidal Self Injury, Attempt Suicide, Personality Disorders
- Trial name
- NCT04905797
- Testing
- Emotional Stop Signal Task, Magnetic Resonance Imaging, World Health Organizations Disability Assessment Schedule (WHODAS 2.0)
- Where
- Sweden
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Region Skane
Suicidal Ideation, Suicide, Attempted
Reducing Suicide Ideation Among Young People
It is Cluster Randomized Control Trial research to examine feasibility and relevance of the modified tool Nae Disha for Life, which will incorporate suicide prevention and resilience to reduce suicide ideation among young people…
- Trial name
- NCT06474312
- Testing
- Nae Disha
- Where
- India
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Suicide, Suicide, Attempted
Improving Firearm Storage in Alaska Native Villages
Rates of suicide among young Alaska Native males are over ten-fold higher than among a similar age cohort in the rest of the United States. A high proportion of these deaths are associated with firearms.
- Conditions
- Suicide, Suicide, Attempted, Wounds and Injuries
- Trial name
- NCT00643812
- Testing
- Installation of gun locker in household
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- University of Washington
Suicide Risk, Suicide Ideation
Momentary Assessment.Tracking Suicidal Ideation
The goal of this observational study is to increase the knowledge base about fluctuations in suicide ideation and its association with relational and contextual factors after hospital discharge in patients with high risk of…
- Conditions
- Suicide Risk, Suicide Ideation, Suicide Prevention, Ecological Momentary Assessment
- Trial name
- NCT05955807
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vestre Viken Hospital Trust
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears