Clinical trials: Suicide and Depression
Major Depressive Disorder
The Effect of Soluble Epoxide Hydrolase (SEH) on Depression
Depression is the most common mental disease and the second leading cause of chronic disease burden, which is closely related to suicidal behavior.
- Trial name
- NCT05575713
- Where
- China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Depression, Suicide
Reaching Out to Distressed Medical Residents, Fellows and Faculty
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and…
- Trial name
- NCT02010866
- Testing
- counseling
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Depression and Suicide Ideation
Development and Feasibility of a Metaverse-based Blended Online Intervention to Prevent Employees' Depression
The goal of this feasibility study is to develop a new metaverse-based blended online intervention using an online program and coaching via metaverse to prevent depression among Generation MZ Employees in South Korea.
- Trial name
- NCT06426342
- Testing
- metaverse-based blended online intervention
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Suicide, Major Depressive Disorder
Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients
This study will try to provide a better understanding of the psychological, cognitive and electrophysiological factors that contribute to suicide in depressed patients.
- Conditions
- Suicide, Major Depressive Disorder, Quantitative EEG (qEEG)
- Trial name
- NCT04104698
- Testing
- Quantitative EEG
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Suicide, Depression
Inflammation and Blood Brain Barrier Integrity as Biomarkers of Suicidal Behavior
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBBBiS (NCT06047613)
- Testing
- Blood samples, Hetero-questionnaires and auto-questionnaires, Magnetic Resonance Imaging (MRI)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation, Depression
Digital Cognitive Behavior Therapy Program for Suicide Prevention
This study evaluates the efficacy of Thrive, a computerized cognitive behavior therapy program, to reduce depression and anxiety symptoms and to reduce suicidal thinking among adults.
- Conditions
- Suicidal Ideation, Depression, Anxiety
- Trial name
- TM2 (NCT03595254)
- Testing
- Thrive
- Where
- United States
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- Montana State University
Major Depressive Disorder, Bipolar Disorder
An Eye Tracking Study of Affective Disorder Patients With Suicide Risk
This research tries to investigate the validity and reliability of eye-tracking technologies by using different paradigms (eg. free-view, pro-saccade and anti-saccade) which served as a novel way of evaluating suicide risk among…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Suicide
- Trial name
- NCT03711045
- Testing
- eye-tracking
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Older Adults (50-90 Years), Mental Health
Project HOPEFUL: A PN-RCT With Implementation Science
This PN-RCT replicates and evaluates an 8-week warm calling treatment (i.e. caring contacts) delivered to older adults receiving home and community-based services (HCBS; classified as "homebound") in 20-30 minute call "dosages"…
- Conditions
- Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning
- Trial name
- NCT07475039
- Testing
- Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Florida
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Depression, Suicide
Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome
Subanesthetic dose of intravenous ketamine (KET) has been found to be highly effective in rapid treatment depression and associated suicidality but its exact mechanism of remains uncertain.
- Trial name
- NCT06698848
- Testing
- ketamin
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital