Clinical trials: Suicide and Self-harm
Suicide, Attempted, Suicidal Ideation
Mobile Technology for Reducing and Preventing Adolescent Suicide
This single-group open-label trial will evaluate the feasibility and preliminary efficacy of a suicide prevention mobile application when used as an adjunct to usual care in adolescents.
- Trial name
- NCT04896593
- Testing
- Smartphone App
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Hartford Hospital
Suicide, Suicide, Attempted
Implementability and Effectiveness of the Safety Planning Intervention for Suicidal Behavior
The Safety Plan Intervention (SPI) has demonstrated to reduce suicide reattempts and to increase the ambulatory follow-up in american war veterans.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT04230434
- Testing
- Safety Plan Intervention
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Major Depressive Disorder, Suicide, Attempted
A Longitudinal Study of Inflammatory Pathways in Depression
Suicide accounts for at least 1 million deaths globally each year. This is likely a significant underestimate, because suicide is under-reported in many countries. In the US, over 42,000 people die from suicide annually.
- Trial name
- NCT04159207
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Van Andel Research Institute
Suicidal Ideation
Building Resilience and Attachment in Vulnerable Adolescents
Suicide is the second leading cause of mortality for Canadian adolescents. Mental health complaints are one of the leading reasons for an emergency department visit at the Children's Hospital of Eastern Ontario and 60% of…
- Trial name
- BRAVA (NCT01925807)
- Testing
- Group Intervention
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Allison Kennedy
Suicidal Behavior, Self-Harm, Deliberate
Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young Adults
This randomized controlled trial will evaluate two approaches to achieving the aspirational goal of Zero Suicide within a health system: 1) Zero Suicide Best Practices initiated through a zero suicide quality improvement…
- Conditions
- Suicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, Suicide
- Trial name
- Step2Health (NCT03092271)
- Testing
- Stepped Care for Suicide Prevention, Zero Suicide Quality Improvement
- Where
- 2 sites in United States
- Volunteers
- 301 people
- Sponsor
- University of California, Los Angeles
Social Isolation, Loneliness
Culture and Well-Being for Latinos
The proposed K23 study is an intervention study using an experimental therapeutics approach. This pilot RCT asks: "Does SOCIAL-ENGAGE increase cultural-social engagement and decrease suicide risk among Spanish-speaking adults?"…
- Conditions
- Social Isolation, Loneliness, Suicidal Ideation
- Trial name
- NCT05244733
- Testing
- Social Engage (S-ENGAGE), The Healthy Lifestyles Education Program
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Rochester
Suicide, Depression
Adaptation of a French E-health Tool for Suicide Prevention in Young Populations
"France's suicide rate is among the highest in Europe, with the young among the more at risk. Several European projects have demonstrated the effectiveness of using e-tools in suicide prevention particularly for hard-to-reach…
- Conditions
- Suicide, Depression, Psychological Distress, Anxiety Disorders
- Trial name
- E-psYouth (NCT04946955)
- Testing
- Application and website with or without promotion
- Where
- France
- Volunteers
- 12,000,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Incurable Cancer Diseases, Other Incurable Diseases
Incurable Ill Patients Attitudes Towards Euthanasia and Assisted Suicide
Euthanasia and assisted dying are of growing interest for patients with incurable diseases. The possible methods are widely discussed by patient-societies, physicians, lawyers, theologians and philosophers.
- Trial name
- ESPIL (NCT00495482)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Klinikum St. Georg gGmbH
Suicidal Intention, Suicidal Ideation
Men and Providers Preventing Suicide (MAPS)
This study will determine if suicidal middle-aged men who use a personalized computer program addressing suicide risk before a primary care visit are more likely to discuss suicide and accept treatment, reducing their suicide…
- Conditions
- Suicidal Intention, Suicidal Ideation, Suicide, Attempted
- Trial name
- NCT02986113
- Testing
- MAPS tailored multimedia patient activation program, Sleep hygiene video, Telephone evidence-based follow-up care
- Where
- 2 sites in United States
- Volunteers
- 93 people
- Sponsor
- University of California, Davis
Bipolar Disorder in Remission, Major Depression in Remission
Seasonality, Chronotype, Impulsivity, and Suicidality in Mood Disorder Patients
The aim of the study is to examine the seasonal variation of suicidal ideation in patients with mood disorders and the trajectory of impulsivity and suicidal ideation in patients with higher seasonality.
- Trial name
- NCT07857213
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University - Cerrahpasa
Suicidal Ideation
Ask Suicide-Screening Questions (ASQ) for Youth With Autism Spectrum and Neurodevelopmental Disorders
Background: Suicide is the second leading cause of death for young people ages 10-24 years. There is no gold standard for evaluating suicidal thoughts and behaviors in young people with autism spectrum disorder (ASD) or other…
- Trial name
- NCT04317118
- Where
- 3 sites in United States
- Volunteers
- 278 people
- Sponsor
- National Institute of Mental Health (NIMH)
Sleep Initiation and Maintenance Disorders, Depression
Improving Sleep and Psychological Functioning in People With Depression and Insomnia
This study will evaluate the safety and effectiveness of treatment with both a sleeping pill and antidepressant medication in improving sleep and psychological functioning in people with depression and insomnia.
- Trial name
- NCT00247624
- Testing
- Eszopiclone, Fluoxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Suicide, Attempted, Suicide Prevention
Attempted Suicide Intervention Treatment and Prevention (SAMIT Program)
Suicide has become a first-order public health concern after the negative impact of coronavirus disease 2019 (COVID-19) on the mental health of the general population.
- Trial name
- SAMIT (NCT06238414)
- Testing
- Early psychotherapeutic intervention
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Autism Spectrum Disorder, Suicidal Ideation
Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors
This pilot randomized controlled trial will recruit 90 autistic adolescents aged 13-18 years with recent suicidal thoughts or behaviors from Geha Mental Health Center in Israel.
- Conditions
- Autism Spectrum Disorder, Suicidal Ideation, Suicidal Behavior, Self-Injurious Behavior
- Trial name
- VSP-AY (NCT07333014)
- Testing
- Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- College of Management Academic Studies
Adolescent - Emotional Problem, Suicide and Self-harm
Parent Intervention for Psychiatrically-Hospitalized Youth
The purpose of the present study is to conduct a pilot randomized clinical trial (RCT) of a parent coaching intervention for parents of youth hospitalized for suicidal ideation, suicide attempt(s), or non-suicidal self-injury.
- Conditions
- Adolescent - Emotional Problem, Suicide and Self-harm, Parenting
- Trial name
- NCT04797455
- Testing
- DBT-Based Parenting Intervention, Treatment as usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Suicide, Suicide and Self-harm
The Use of Voice-Based AI in 988 Crisis Counseling
Effective training requires repeated opportunities for skills practice with performance-based feedback, which is challenging to provide at scale.
- Trial name
- NCT06299384
- Testing
- LyssnCrisis
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Lyssn.io, Inc.
Self-injury, Suicidal Ideation and Behavior
Pilot Trial of an Emotion Regulation and Executive Functioning Intervention for Self-Injurious Thoughts and Behaviors (SITBs) in Children
The goal of this study is to develop and test an outpatient intervention for preadolescents (ages 7-12) with self-injurious thoughts and behaviors (SITBs). The main questions it aims to answer are: 1.
- Conditions
- Self-injury, Suicidal Ideation and Behavior, Executive Functioning, Emotion Regulation
- Trial name
- NCT07281365
- Testing
- Treatment as usual (TAU), Preadolescent SITB Intervention
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Colorado, Denver
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Depression, Anxiety
Mental Health First Aid for College Students
Most college students with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Eating Disorders
- Trial name
- NCT02021344
- Testing
- Mental Health First Aid
- Where
- United States
- Volunteers
- 2,543 people
- Sponsor
- University of Michigan
Suicide Attempt, Suicide Ideation
A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and preliminary efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors…
- Trial name
- NCT06967545
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital