Clinical trials: Suicide and Self-harm
Suicidal Ideations, Suicidal Attempt
Safety Plan in Emergency Department to Prevent Suicidal Attempt Recidive
Suicide is one of the leading causes of death worldwide, with more than 700 000 deaths due to suicide every year, according to the World Health Organisation (WHO).
- Conditions
- Suicidal Ideations, Suicidal Attempt, Prevention, Safety Plan
- Trial name
- PLUS (NCT06499337)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier St Anne
Suicide, Attempted
Effect of Telephone Follow-up on Repeated Suicide Attempt in Patients
Attempted suicide is a major public health problem, and the efficacies of current postvention protocols vary. The investigators evaluated the effectiveness of telephone follow-up of patients referred to an emergency psychiatric…
- Trial name
- EXBRAYAT (NCT02932709)
- Testing
- suicide attempt
- Where
- France
- Volunteers
- 876 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Suicide, Attempted, Suicidal Ideation
A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic
The primary objective of this study is to assess the effectiveness of a digital intervention in reducing suicide attempts.
- Trial name
- NCT05144685
- Testing
- OTX-202, OTX-000, Treatment as Usual
- Where
- 6 sites in United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Oui Therapeutics, Inc.
Depression, Anxiety
Bridging the Gap to Improve Mental Health Treatment Utilization
Bridging the Gap aims to improve access to effective mental health treatment in a primary care setting through utilization of single session growth mindset interventions for parents and for youths.
- Conditions
- Depression, Anxiety, Adolescent Behavior, Suicidal Ideation
- Trial name
- NCT04558489
- Testing
- IPR + GMI
- Where
- United States
- Sponsor
- University of Pittsburgh
Suicide and Self Harm
Implementing a Brief Suicide Intervention for High Risk Youth With Front-Line Juvenile Justice Staff
A youth's contact with the juvenile justice system represents an opportune moment for suicide screening and brief suicide intervention for indicated youth.
- Trial name
- NCT02981420
- Testing
- Safety planning
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Suicidal Ideation/Behavior, Depression
Randomized, Placebo-controlled Multicenter Trial of Lithium Plus Treatment as Usual (TAU) for Acute Suicidal Ideation and Behavior in Patients With Suicidal Major Depressive Episode
The primary hypothesis of this confirmatory study is that lithium therapy will acutely decrease suicidal ideation and/or suicidal behaviour in inpatients with a major depressive episode (MDE, unipolar and bipolar disorder…
- Trial name
- NCT02039479
- Testing
- Lithium Carbonate
- Where
- 5 sites in Germany
- Volunteers
- 254 people
- Sponsor
- Technische Universität Dresden
Psychosis, Suicide Prevention
Cognitive AppRoaches to coMbatting Suicidality
This is a randomised controlled trial which investigates the effectiveness of CARMS (Cognitive AppRoaches to coMbatting Suicidality) therapy in reducing suicidal thoughts and how well CARMS works in practice within the NHS.
- Conditions
- Psychosis, Suicide Prevention, Suicidality
- Trial name
- CARMS (NCT03114917)
- Testing
- Cognitive AppRoaches to coMbatting Suicidality (CARMS)
- Where
- 4 sites in United Kingdom
- Volunteers
- 329 people
- Sponsor
- University of Manchester
Non-Suicidal Self Injury, Suicide
Dialectical Behavioral Therapy in Juvenile Justice
Self-injurious thoughts and behaviors (SITBs) are a serious public health concern, particularly for youth involved in the juvenile justice system (JJS), which the Georgia State Juvenile Justice System (GAJJS) intends to address…
- Conditions
- Non-Suicidal Self Injury, Suicide, Self-harm, Emotion Regulation
- Trial name
- DBT-A&JJS (NCT05583279)
- Testing
- Dialetical Behavioral Therapy for Adolescents
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Catholic University of America
Alcohol Drinking, Suicide, Attempted
Brief Alcohol Intervention and mHealth Booster for Suicidal Adolescents
The primary goal of this study is to test the acceptability and feasibility of iASIST (integrated Alcohol and Suicide Intervention for Suicidal Teens), a novel adjunctive intervention for alcohol use and alcohol-related suicidal…
- Conditions
- Alcohol Drinking, Suicide, Attempted, Adolescent Behavior
- Trial name
- NCT03607318
- Testing
- iASIST
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Post Traumatic Stress Disorder, Suicidal Ideation
Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD)
Patients with PTSD, and frequent nightmares, and mild-moderate suicidal ideation, who are already taking a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI) will be randomized to…
- Conditions
- Post Traumatic Stress Disorder, Suicidal Ideation, Nightmares
- Trial name
- REST-ON PTSD (NCT02199652)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Augusta University
Palliative Care, End of Life
Requests for Euthanasia and Assisted Suicide
This study take place in the palliative care units of Burgundy-Franche-Comté regions and at the Maison Médicale Jeanne Garnier. The main aim of this project is to analyze and understand the meaning of explicit requests to hasten…
- Conditions
- Palliative Care, End of Life, Euthanasia, Assisted Suicide
- Trial name
- DESA (NCT02845817)
- Testing
- Qualitative research
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Suicide, Attempted, Functioning, Psychosocial
iFD-SuRvivE funCtiONal effiCacy and bIologicaL corrElates (RECONCILE Study)
The goal of this clinical trial is to assess the effectiveness of an original intervention 'Functional Recovery in Depression and Suicide Risk Prevention Based on Emotion Regulation and Values: A Group Program' (from the original…
- Conditions
- Suicide, Attempted, Functioning, Psychosocial, Cognition, Neuroimaging
- Trial name
- RECONCILE (NCT05655390)
- Testing
- 'Functional Recovery in Depression and Suicide Risk Prevention Based on Emotion Regulation and Values: A Group Program'
- Where
- 4 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Iria Grande
Child Development Disorders, Pervasive
Assessing Suicide Risk in Adolescents With Developmental Delays
Background: Currently, there is no standard method to study suicide risk in youth with developmental delays or intellectual disabilities (DD/ID).
- Trial name
- NCT01517126
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Suicidal Ideation
Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation
Background. Suicidal ideation and depressive symptoms are highly prevalent among adolescents, with suicide representing a leading cause of death in this age group worldwide.
- Trial name
- NCT07063914
- Testing
- Reframe-IT and CARIBOU
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de los Andes, Chile
Suicide
Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial
This study will enroll patients presenting to the emergency department with acute suicidal ideation meeting inclusion and exclusion criteria.
- Trial name
- LDK-SI (NCT01892995)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Suicide Prevention
Feasibility Study of a Combined Intervention for Suicidal Inpatients in Psychiatric Crisis Units.
Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap . Hospitalization offers a crucial opportunity for life-preserving intervention .
- Trial name
- HOPAIR (NCT07119671)
- Testing
- HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hôpital le Vinatier
Treatment Resistant Depression, Suicidal Ideation
The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation
This study aims to explore the safety and tolerability of a single dose of psilocybin (25mg) administered under supportive conditions to adult participants with TRD and chronic suicidal ideation
- Trial name
- NCT05220410
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sheppard Pratt Health System
Depression, Cancer Patients and Depression and Suicide
Improvement of Depression in Terminal Cancer Patients
This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients.
- Conditions
- Depression, Cancer Patients and Depression and Suicide, Life Quality
- Trial name
- IDTCP (NCT06785623)
- Testing
- Gastrodia elata Blume water extract
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Suicide Attempt
The 10-years REPEATERS Cohort of French Adolescents
Losing contact with adult suicide attempters in the year after the suicide attempt (SA) increases the risk of recurrence. The situation with adolescents is unknown.
- Trial name
- NCT02887170
- Where
- France
- Volunteers
- 246 people
- Sponsor
- Central Hospital, Nancy, France
Suicide, Suicidal Ideation
Telehealth to Reduce Suicidality and Improve HIV Care Engagement in Tanzania
The overall objectives of the proposed research are to develop a brief telehealth counseling intervention to provide support for people living with HIV and experiencing suicidal ideation, and to support HIV care engagement.
- Conditions
- Suicide, Suicidal Ideation, HIV Infections, Adherence, Medication
- Trial name
- NCT04696861
- Testing
- IDEAS for Hope, Enhanced Standard of Care (Safety Planning)
- Where
- 2 sites in Tanzania
- Volunteers
- 60 people
- Sponsor
- Duke University