Clinical trials: Suicide and Self-harm
Adolescent - Emotional Problem, Suicide and Self-harm
DBT-Based Parenting Intervention for Parents of Youth at Risk for Suicide
The purpose of the present study is to conduct a pilot randomized clinical trial (RCT) of an 8-10 session DBT-based parenting intervention (DBT PI) plus standard Dialectical Behavior Therapy delivered in the context of an…
- Conditions
- Adolescent - Emotional Problem, Suicide and Self-harm, Parenting
- Trial name
- NCT04132284
- Testing
- DBT-Based Parenting Intervention, Treatment as Usual
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Stanford University
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Community Adolescents at Risk for Depression and Suicide
Application and Evaluation of Group Cognitive Intervention for Depressed Adolescents
Cognitive behavioral therapy (CBT) is effective and CBT with parental involvement has potential in preventing and treating adolescent depression.
- Trial name
- NCT00946413
- Testing
- CBT plus parent education, CBT alone
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- Taipei Medical University Hospital
Suicide Ideation, Suicide Attempt
Plan and Protect: Safety Planning for Teens in Rural Emergency Departments
The goal of this observational study is to determine whether implementing a culturally sensitive, tablet-based safety planning program called Plan \& Protect (P\&P) within rural emergency departments can improve home safety and…
- Trial name
- NCT07325474
- Testing
- Plan & Protect safety planning intervention, Care as usual
- Where
- 6 sites in United States
- Volunteers
- 550 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicidal Ideation and Behavior, Impulsivity
Title: "Intervention Based on Didactic Model for Suicidal Behavior in the Framework of Impulsivity and Ideations."
Suicide has become a major public health problem among young people around the world. This study will examine the effects of higher secondary school-based suicide prevention (HSSSP) program on youth suicidal thoughts and…
- Trial name
- NCT05324670
- Testing
- Didactic model for suicidal behavior in the framework of impulsivity and ideations
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- International Islamic University, Islamabad
Suicidal Behaviors, Suicide Ideation
Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors
The primary aim of the project is to test the efficacy of BCBT delivered via a digital platform (i.e., smartphone) to Servicemembers with recent suicidal ideation and/or suicide attempts presenting to primary care clinics.
- Conditions
- Suicidal Behaviors, Suicide Ideation, Depression/Anxiety
- Trial name
- NCT06318962
- Testing
- Aviva
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Memphis
Suicide Prevention
A Novel Cognitive Reappraisal Intervention for Suicide Prevention
The goal of this trial is to refine and test a novel emotion-regulation based psychosocial intervention designed to reduce suicide risk in middle-aged and older adults (50-90 years old) who have been discharged after a…
- Trial name
- CRISP (NCT03026127)
- Testing
- Cognitive Reappraisal Intervention for Suicide Prevention, Supportive Therapy
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Weill Medical College of Cornell University
Major Depressive Disorder
Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk
Joiner's interpersonal theory of suicide postulates that the wish of death comes from feelings of perceived burdensomeness and thwarted belongingness.
- Trial name
- R2D2 (NCT04461327)
- Testing
- Painful stimulations of major depressive patients, Blood sample, Clinical assessment
- Where
- 2 sites in France
- Volunteers
- 144 people
- Sponsor
- University Hospital, Montpellier
BPH, Depression
5 Alpha Reductase Inhibitors And The Risk Of Suicide And Depression
In December 2015, Health Canada issued a warning about a potential relationship between suicide and finasteride use and called for further research.
- Conditions
- BPH, Depression, Suicide
- Trial name
- NCT02876757
- Testing
- 5ARI
- Volunteers
- 186,394 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Insomnia, Depression
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
There is a strong association between sleep disturbance and suicidal thoughts and behaviors. Sleep disturbance is also highly comorbid with other common conditions associated with suicide such as depression and posttraumatic…
- Conditions
- Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
- Trial name
- NCT02248675
- Testing
- CBT-I, TAU
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Anxiety Disorders, Depression
Pharmacogenomics of Antidepressant Response in Children and Adolescents
This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications.
- Conditions
- Anxiety Disorders, Depression, Eating Disorders, Obsessive-Compulsive Disorder
- Trial name
- PARCA (NCT00516932)
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Duke University
Mild Traumatic Brain Injury, Suicidal Ideation
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
The investigators hope to develop a treatment for suicidal ideation (SI), impulsivity and functional impairments (such as difficulties in social and work settings) that occur after a mild traumatic brain injury (mTBI).
- Conditions
- Mild Traumatic Brain Injury, Suicidal Ideation, Impulsivity
- Trial name
- NCT05647044
- Testing
- intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Suicidal Behavior, Self-Harm, Deliberate
Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young Adults
This randomized controlled trial will evaluate two approaches to achieving the aspirational goal of Zero Suicide within a health system: 1) Zero Suicide Best Practices initiated through a zero suicide quality improvement…
- Conditions
- Suicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, Suicide
- Trial name
- Step2Health (NCT03092271)
- Testing
- Stepped Care for Suicide Prevention, Zero Suicide Quality Improvement
- Where
- 2 sites in United States
- Volunteers
- 301 people
- Sponsor
- University of California, Los Angeles
Chronic Pain, Suicidal Ideation
Mindfulness for Pain and Suicide
The proposed study will assess the feasibility and acceptability of a mindfulness-based intervention to reduce functional impairment from chronic pain and risk of suicide.
- Conditions
- Chronic Pain, Suicidal Ideation, Suicide, Attempted, Opioid Use
- Trial name
- NCT05286112
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT), Health Education
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Canandaigua VA Medical Center
Depression, Suicide and Self-harm
Telehealth Behavioral Activation for Teens
Behavioral activation is one such empirically supported intervention. Derived from cognitive-behavioral therapy, a well-established treatment for depression, behavioral activation uses psychoeducation and skill-building to…
- Conditions
- Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild
- Trial name
- NCT06273995
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Baylor College of Medicine
Mood Disorder of Depressed Type
The Effects of Logotherapy in Adolescents With Mood Disorders
Logotherapy can help people find their meaning in life and help people reduce their suicidal ideation. Suicide was the second leading cause of death for 15-24 year-olds.
- Trial name
- NCT05797428
- Testing
- logotherapy
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Depression, Suicide
Intranasal Ketamine for Late-Life Depression and Suicidal Ideation
The investigators of this study plan to investigate the feasibility and efficacy of repeated doses of intranasal ketamine in severely depressed patients who are at least 65 years of age and experiencing suicidal ideation.
- Conditions
- Depression, Suicide, Suicidal Ideation
- Trial name
- NCT02295787
- Testing
- Ketamine
- Sponsor
- Massachusetts General Hospital
Suicide, Attempted
Teachable Moment Brief Intervention for Suicide Attempt Survivors in an Inpatient Setting
This study is looking at the helpfulness of a brief treatment targeting suicidality (Teachable Moment Brief Intervention [TMBI]) and experimental pain responses in an inpatient population as well as collecting comparison data…
- Trial name
- TMBI-IP (NCT03600532)
- Testing
- Teachable Moment Brief Intervention (TMBI)
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Tulsa
Suicidal Ideation
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a study group of 150 civilian and Veteran participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Trial name
- PRE-EMPT (NCT07484906)
- Testing
- fMRI Neurofeedback, Accelerated theta burst stimulation, Psilocybin assisted therapy
- Sponsor
- University of New Mexico
Suicide, Attempted
Clinical and Actigraphic Profile of Young Patients Admitted for Attempted Suicide
An excess suicide-related morbidity is observed among young people in the Picardie region, as reflected by the > 100% occupation rate of the Amiens University Hospital Adolescent Medicine Unit
- Trial name
- ACTIHUMEUR (NCT02803632)
- Testing
- questionnaires, actigraphic recording
- Where
- 2 sites in France
- Volunteers
- 98 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens