Clinical trials: Superficial Basal Cell Carcinoma
Basal Cell Carcinoma, Superficial Basal Cell Carcinoma
Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma
Optical coherence tomography guided laser treatment of basal cell carcinoma
- Conditions
- Basal Cell Carcinoma, Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
- Trial name
- NCT04744935
- Testing
- 1064 nm long-pulse Nd:YAG laser
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Christopher Zachary
BCC, BCC - Basal Cell Carcinoma
Use of Jet-injection in Photodynamic Therapy for Basal Cell Carcinoma
The purpose of this study is to find out whether injecting ALA into the skin with a jet-injection device and activating the drug with light is a safe treatment that causes few or mild side effects in people with basal cell…
- Conditions
- BCC, BCC - Basal Cell Carcinoma, Basal Cell Carcinoma, Basal Cell Cancer
- Trial name
- NCT04552990
- Testing
- Jet injection of ALA, Surgical excision, Illumination
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
High Intensity Focused Ultrasound vs. Cryotherapy in the Treatment of Basal Cell Carcinomas and Bowen's Disease in Adults
This prospective, randomized, controlled, and single-blinded non-inferiority clinical trial compare the efficacy and tolerability of high intensity focused ultrasound (HIFU) to standard cryotherapy in the treatment of low-risk…
- Conditions
- Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma, Bowen's Disease, BCC
- Trial name
- HIFUvsCRYO (NCT07384078)
- Testing
- High Intensity Focused Ultrasound, Cryotherapy
- Where
- Finland
- Volunteers
- 294 people
- Sponsor
- Jussi Salonen
Superficial Basal Cell Carcinoma
Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT).
The aim of this study is to test the safety and efficacy of photodynamic therapy (PDT) with the medication Ameluz® performed with the PDT-lamp BF-RhodoLED® in comparison to the respective placebo treatment for superficial basal…
- Trial name
- NCT03573401
- Testing
- Photodynamic therapy (PDT) (ALA-PDT, Ameluz®-PDT)
- Where
- 18 sites in United States
- Volunteers
- 187 people
- Sponsor
- Biofrontera Inc.
Superficial Basal Cell Carcinoma, Squamous Cell Carcinoma in Situ
5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
The investigators will compare the application of two different creams for the treatment of low-risk skin cancers-superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis).
- Trial name
- NCT05381597
- Testing
- Combination cream of 5-fluorouracil and calcipotriene, 5-fluorouracil cream
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston University
Superficial Basal Cell Carcinoma
Dose-Ranging Clinical Trial of Topical Creams Containing API 31510 for the Treatment of Superficial Basal Cell Carcinoma
The purpose of this study is to determine the safety and tolerability of pharmaceutical compound (API 31510) topical cream topically applied to superficial basal cell carcinomas to obtain preliminary efficacy data for the…
- Trial name
- NCT00604890
- Testing
- API 31510 3% Topical Cream, API 31510 1.5% Topical Cream
- Where
- 11 sites in United States
- Volunteers
- 186 people
- Sponsor
- BPGbio
Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
Safety and Efficacy Evaluation of AIV001 in Nonmelanoma Skin Cancer of the Low Risk Basal Cell Carcinoma Subtype
To evaluate safety and efficacy of AIV001 treatment on low-risk Nonmelanoma Skin Caner of the basal cell carcinoma subtype.
- Conditions
- Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma, Nonmelanoma Skin Cancers
- Trial name
- NMSC (NCT04470726)
- Testing
- AIV001, AIV001 suspension
- Where
- 4 sites in United States
- Volunteers
- 26 people
- Sponsor
- AiViva BioPharma, Inc.
Superficial Basal Cell Carcinoma
Metvix Photodynamic Therapy (PDT) Versus Cryotherapy in Participants With Primary Superficial Basal Cell Carcinoma
The purpose of this study was to compare the efficacy of Photodynamic Therapy (PDT) methyl aminolevulinate (MAL) cream to cryotherapy, in treatment of participants with primary superficial basal cell carcinoma (BCC).
- Trial name
- NCT00469417
- Testing
- Metvix® cream, Hand held liquid nitrogen spray cryotherapy
- Where
- 14 sites in Austria, Belgium and 5 more
- Volunteers
- 120 people
- Sponsor
- Galderma R&D
Superficial Basal Cell Carcinoma
Proof of Concept Study to Access Superficial Basal Cell Carcinoma in Adults
This is a Phase 2, Single-Arm, Open-Label, Single Center, Proof of Concept Study to Assess Efficacy and Safety of Tirbanibulin Ointment 1% in Adult Subjects with superficial basal cell carcinoma (sBCC) on the neck, trunk, or…
- Trial name
- NCT05713760
- Testing
- Tirbanibulin Ointment 1%
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Austin Institute for Clinical Research
Carcinoma, Basal Cell, Porokeratosis, Disseminated Superficial Actinic
Cytodiagnosis of Basal Cell Carcinoma and Actinic Keratosis Using Papanicolaou and May-grunwald-giemsa Stained Tissue Smear
The purpose of this study is to compare and evaluate the diagnostic performance of scrape cytology using two different cytological staining techniques, and to evaluate additional touch imprint cytology with that of histopathology…
- Trial name
- NCT00218868
- Testing
- Skin scrape
- Where
- Norway
- Volunteers
- 66 people
- Sponsor
- Norwegian University of Science and Technology
Superficial Basal Cell Carcinoma
A Patient Decision Aid for Patients With Superficial Basal Cell Carcinoma
A patient decision aid (PDA) was tested in a population of patients with superficial basal cell carcinoma. This study evaluates whether the use of a PDA improved outcomes like decisional conflict and knowledge.
- Trial name
- NCT05628714
- Testing
- Patient decision aid for patients with superficial basal cell carcinoma
- Where
- Netherlands
- Volunteers
- 222 people
- Sponsor
- Maastricht University Medical Center
Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma
This study will be a multicenter, prospective, open label, one-arm study intended to assess the Safety and Efficacy of EscharEx (EX-02) in the treatment of Basal Cell Carcinoma.
- Trial name
- NCT05157763
- Testing
- EscharEx 5% (EX-02 formulation)
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- MediWound Ltd
Nodular Basal Cell Carcinoma, Superficial Basal Cell Carcinoma
Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser
Laser therapy for basal cell carcinoma may be a superior option for patients who do not wish to or cannot tolerate other treatment modalities such as topical chemotherapeutics or surgery.
- Trial name
- BCC (NCT02270645)
- Testing
- 595/1064 multiplex laser
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Miami
Bowen's Disease, Superficial Basal Cell Carcinoma
Laser Assisted Drug Delivery in the Treatment of Superficial Non Melanoma Skin Cancer: a Randomized Controlled Trial
Photodynamic therapy (PDT) is a well established treatment option for superficial non melanoma skin cancer, such as superficial basal cell carcinoma (sBCC) and Bowen Disease (BD).
- Trial name
- NCT03012009
- Testing
- full ablative CO2 laser, fractional ablative CO2 laser, MAL
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- University Hospital, Ghent
Superficial Basal Cell Carcinoma
PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities
This study is primarily designed to investigate whether treatment, once daily for up to three consecutive days, with PEP005 (ingenol mebutate) Gel, 0.05% will be safe and tolerable in patients with superficial Basal Cell…
- Trial name
- NCT01325688
- Testing
- PEP005 (ingenol mebutate) Gel, 0.05%, Aluminium disk, OpSite(TM) disk
- Where
- 7 sites in Australia
- Volunteers
- 75 people
- Sponsor
- Peplin
Superficial Basal Cell Carcinoma
To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC
The purpose of this study is to determine maximum tolerated dose level (MTD) of PEP005 Topical Gel for the treatment of superficial basal cell carcinoma on the trunk
- Trial name
- NCT00432185
- Testing
- PEP005
- Where
- 9 sites in United States
- Volunteers
- 117 people
- Sponsor
- Peplin
Sporadic Superficial and Nodular Skin Basal Cell Carcinomas
To Evaluate the Safety, Local Tolerability, PK and PD of LDE225 on Sporadic Superficial and Nodular Skin Basal Cell Carcinomas (sBCC)
This was a double-blinded, randomized, vehicle-controlled study in sporadic superficial BCC (sBCC) and nodular BCC (nBCC) patients which consisted of a 21-day screening period, a treatment period of 6 weeks (topical 0.75% LDE225…
- Trial name
- NCT01033019
- Testing
- LDE225 0.75%, Vehicle
- Where
- 4 sites in Australia, Austria
- Volunteers
- 25 people
- Sponsor
- Novartis Pharmaceuticals
Superficial Basal Cell Carcinoma
Cure Rates of Superficial Basal Cell Carcinoma (BCC) EDC
This is a prospective, randomized clinical trial conducted at the Unviersity of Wisconsin (UW) Dermatology Clinic located at 1 S. Park Street, Madison, WI 53715. There are no controls.
- Trial name
- NCT00994240
- Testing
- Electrodessication & Curettage
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Wisconsin, Madison
Superficial Basal Cell Carcinoma
Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate
Skin cancer is the most common cancer in Caucasians, and a basal cell carcinoma (BCC) being the most common skin cancer with around 44,000 new tumours per year, and its incidence is still rising.
- Trial name
- NCT01491711
- Testing
- Methylaminolevulinate PDT in 2 sessions, Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
- Where
- 3 sites in Netherlands
- Volunteers
- 162 people
- Sponsor
- Maastricht University Medical Center
Superficial Basal Cell Carcinoma
Open-label Study to Evaluate Clearance of Superficial Basal Cell Carcinoma After Use of Imiquimod 5% Cream
An open-label study to evaluate the safety and the ability of Imiquimod 5% cream, applied topically, to clear superficial basal cell carcinoma and to keep it clear for 5 years of follow-up.
- Trial name
- NCT00189306
- Testing
- Imiquimod 5% cream
- Where
- 18 sites in Australia, New Zealand
- Volunteers
- 169 people
- Sponsor
- Graceway Pharmaceuticals, LLC