Clinical trials: Supplementation, active
Malnourished Children, Stunting of Growth
Comprehensive Nutritional Support for Children in Zambia (ZamCNC) - A Pilot Investigation
In a recently completed intervention study, more than 50% of children in Lusaka were found to be stunted by age two, even when nutritional supplements were provided.
- Trial name
- ZamCnC (NCT07153913)
- Testing
- Intensive growth support
- Where
- Zambia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Günther Fink
Phenylketonuria
Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria
Effect of L-carnitine supplementation on phenylalanine and brain-derived neurotrophic factor levels in infants and children with phenylketonuria L-carnitine is mainly obtained from foods such as red meat and milk that are limited…
- Trial name
- NCT06901323
- Testing
- L-carnitine
- Where
- Egypt
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Type 1 Diabetes Mellitus
Effect of Dietary Carbohydrate Content and Inulin-Fructooligosaccharide Supplementation on Glycemic Control in Individuals With Type 1 Diabetes Mellitus
Diabetes is a chronic metabolic disease in which nutrients such as carbohydrates, fats and proteins cannot be utilized sufficiently due to the inability to produce insulin or defects in the effect of the produced insulin.
- Trial name
- NCT07673523
- Testing
- fructooligosaccharide and inulin, Dietary carbohydrate 30%, Dietary carbohydrate 50-55%
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Ulcerative Colitis
Multi-Strain Probiotics Supplementation With Standard Care in Mild to Moderate Ulcerative Colitis
Probiotics are one of the adjunctive treatments that have been extensively explored for Ulcerative colitis (UC) disease management.
- Trial name
- NCT06595719
- Testing
- Multi-Strain Probiotics
- Where
- Malaysia
- Volunteers
- 124 people
- Sponsor
- National University of Malaysia
The Effects of Sodium Bicarbonate Supplementation on Endurance Performance in Recreational Female Runners
Sodium Bicarbonate Intake on Endurance Performance
Sodium bicarbonate (SB) is one of the ergogenic aids that enhance short-duration, high-intensity sports performance by improving the buffering system.
- Trial name
- NCT06826222
- Testing
- Sodium Bicarbonate (NaHCO3), Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Adult Participants
Acute Effects of Alpha-glycerylphosphorylcholine (A-GPC) on Lower Body Muscular Performance.
The purpose of the present study was to examine the effectiveness of acute A-GPC supplementation on upper and lower body muscular strength, endurance, power, and global levels of activation.
- Trial name
- A-GPC (NCT07397273)
- Testing
- L-Alpha glycerylphosphorylcholine, Microcrystalline Cellulose
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northern Illinois University
Ulcerative Colitis (Disorder)
Sodium Butyrate and Kluyveromyces Marxianus Supplementation in Inflammatory Bowel Disease
The goal of this clinical trial is to learn if a dietary supplement called ButyMixx can help people with ulcerative colitis in remission feel better and keep their intestines less inflamed.
- Trial name
- Butymixx (NCT07591012)
- Testing
- Butyrate
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova
Anovulatory Infertility
Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome
Poly cystic Ovarian Syndrome (PCOS) is an endocrine disorder of reproductive age defined by "the presence of any two out of three criteria: oligo and/or anovulation, excess androgen activity and/or polycystic ovarian morphology…
- Trial name
- NCT06045351
- Testing
- Vitamin D, Active Comparator
- Where
- Pakistan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Malnutrition in Elderly, Oncological Patients
Impact of Specific Oligomeric Supplementation in Oncologic Patients Undergoing Radiotherapy With Malnutrition or at Risk.
An observational, prospective, multicenter study to be conducted in 5 hospitals in Spain. Patients with cancer undergoing radiotherapy are malnourished or at risk of malnutrition.
- Conditions
- Malnutrition in Elderly, Oncological Patients, Digestive Disorders
- Trial name
- NORMA (NCT07035132)
- Testing
- Oral supplementation with nutritional oligomeric formula
- Where
- 4 sites in Spain
- Volunteers
- 132 people
- Sponsor
- Outcomes'10
Bronchopulmonary Dysplasia (BPD)
Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants
The Impact of Omega-3 (DHA - Docosahexaenoic Acid) and Omega-6 (ARA - Arachidonic Acid) Supplementation on the Development of Bronchopulmonary Dysplasia in Extremely and Very Preterm Infants (24-29 weeks of gestational age).
- Trial name
- PRELUDE (NCT07652684)
- Testing
- Enteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding, Standard care and feeding
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- Aristotle University Of Thessaloniki
Locally Advanced Cervical Cancer
Curcumin Supplementation in Cervical Cancer
Brief Summary. The goal of this pilot study is to learn about the effect of curcumin supplementation in locally advanced cervical cancer patients.
- Trial name
- NCT06080841
- Testing
- Curcumin, Curcumin + Piperine
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- National Institute of Cancerología
Rotator Cuff Tears, Rotator Cuff Injuries
Estradiol Supplementation and Rotator Cuff Repair
Rotator cuff tears in the shoulder are common causes of pain and disability, often fail to heal with surgery, and tears, worse outcomes after surgery, and failure of healing are associated with estradiol deficiency.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Syndrome, Menopause Related Conditions
- Trial name
- ESTRCR (NCT06318403)
- Testing
- Transdermal estrogen, Rotator Cuff Repair Surgery
- Volunteers
- 58 people
- Sponsor
- University of Utah
Exercise-induced Muscle Soreness, Exercise-induced Joint Pain
Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense Exercise
Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery.
- Conditions
- Exercise-induced Muscle Soreness, Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Cartilage Turnover
- Trial name
- NCT07766720
- Testing
- NEM® brand eggshell membrane powder, curQ+® brand highly absorbable curcumin, NEM® plus curQ+® combination
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Fracture Femur, Fracture Tibia
Oral Supplementation With a Formulation Based on Cetylated Fatty Acids for Post-fracture Long Bone Healing
This clinical study aims to evaluate the potential benefits of a formulation based on Cetylated Fatty Acids in improving fracture healing of long bones in the lower limbs.
- Trial name
- CETIULTRA-BONE (NCT07299851)
- Testing
- CFA-based food supplement
- Where
- 6 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Pharmanutra S.p.a.
Hypotestosteronism, Palliative Care
Testosterone Supplementation in Patients in Best Supportive Care: Impact on Quality of Life
This is a monocentric, single-arm prospective pilot study that will enrol hypogonadal (testosterone < 231 ng/dL) male subjects in best supportive care, with no further therapeutic options and no need for resuscitation.
- Trial name
- TestoSup (NCT07143279)
- Testing
- Sustanon 250
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Jules Bordet Institute
Birth Weight
Healthy Mums, Healthy Babies: Multiple Micronutrient Supplementation in Ethiopia
Background: This programme effectiveness study responds to the need for evidence on the effect on birthweight of switching from iron-folic acid supplementation (IFA) to multiple micronutrient supplementation (MMS) as part of…
- Trial name
- NCT05708183
- Testing
- Multiple micronutrient supplementation (MMS), Iron folate supplementation (IFA)
- Where
- 6 sites in Ethiopia
- Volunteers
- 25,620 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Ketosis, Metabolic, Immune Functions
The Effect of Acute Exogenous Oral Ketone Supplementation on Immune Cells Function and Immune Cells Histone Β-hydroxybutyrylation
To conduct a single-arm pilot study to determine how acute ingestion of an exogenous ketone monoester supplement alters the histone lysine β-hydroxybutyrylation and immune function in healthy human monocytes and lymphocytes.
- Conditions
- Ketosis, Metabolic, Immune Functions, Histone Deacetylase (HDAC) Activity
- Trial name
- Acute_Ketone (NCT06590623)
- Testing
- Ketone Monoester (KE)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers
This clinical trial evaluates how propionate and butyrate supplementation alters intestinal health in healthy volunteers and whether it would be feasible to administer these supplements to patients undergoing allogeneic…
- Conditions
- Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT07611370
- Testing
- Biospecimen Collection, Microencapsulated Sodium Butyrate, Microencapsulated Sodium Propionate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Allergic Rhinitis, Allergic Rhinitis (AR)
Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis
The goal of this clinical trial is to learn if taking probiotics, vitamin D, or both together can help lower symptoms of allergic rhinitis (AR) and improve quality of life in adults.
- Trial name
- NCT07115342
- Testing
- Standard Allergic Rhinitis Treatment, Combined Vitamin D and Probiotics Supplementation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Neuromotor Dysphagia After Acute Stroke
The Cooling Sensation Safe Deglution Study
Dysphagia is a common complication in patients who have suffered a cerebrovascular accident (CVA), with an incidence ranging from 29% to 81%.
- Trial name
- NCT06936501
- Testing
- Traditional flavor ONS (vanilla or strawberry, by choice), Refreshing and stimulating flavor ONS (mango-peppermint or lemon-mint, by choice)
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud