Clinical trials: Supplements
Healthy Volunteers
Study to Evaluate the Physiological Effects on the Skin of 3 Food Supplements Versus Placebo in 40-60 Years Old Female Subjects
The objective is to evaluate the effects on the skin of 3 foods supplements compared to placebo after daily intake for 3 months in female subjects presenting healthy skin.
- Trial name
- NCT06254209
- Testing
- Botanicals extracts
- Where
- France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Nexira
Child Malnutrition
7-Day vs 1-Day Packaging for Small Quantity Lipid-Based Nutrient Supplements in Ghana (SQLNS:7D-1D Comparison)
This cluster-randomized crossover trial evaluates whether the packaging format of small-quantity lipid-based nutrient supplements (SQ-LNS) affects caregiver adherence and acceptability when SQ-LNS are delivered through routine…
- Trial name
- SQLNS:7Dv1D (NCT07129109)
- Testing
- small-quantity lipid-based nutrient supplements (SQ-LNS)
- Where
- Ghana
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Obesity-related Poor Sperm Quality, Gut Microbiota
Effects of Soluble Fiber Supplements on Sperm Quality in Males With Obesity: a Randomized Trial
Obesity-related poor sperm quality is a significant public health issue, acting as a major contributor to male infertility. Dietary intervention has emerged as an effective strategy to manage obesity and improve sperm quality.
- Trial name
- NCT07112248
- Testing
- inulin
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Hypovitaminosis D, Insulin Resistance
Comparative Effectiveness of Vitamin D and Repletion Strategies
The importance of vitamin D (VitD) in the prevention and treatment of human health conditions has gained increased attention in recent years.
- Conditions
- Hypovitaminosis D, Insulin Resistance, Diabetes
- Trial name
- CEDARS (NCT01524874)
- Testing
- Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Cardiovascular Diseases, Osteoporosis
A Study on the Impact of Calcium on Woman's Vascular Health
The overarching aim of this randomized clinical trial is to estimate the effect of dietary intake of calcium as compared to supplemental calcium on the vascular system and markers of vascular and bone health in postmenopausal…
- Trial name
- NCT01731340
- Testing
- Calcium Citrate, Low Dietary Calcium, High Dietary Calcium
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Iron-deficiency, Iron Deficiency Anemia
Meals to Improve Absorption of Iron Supplements
One of the targeted objectives of Healthy People 2020 is to reduce iron deficiency among women of reproductive age (WRA). Consuming foods rich in iron and/or oral iron supplementation is typically recommended to improve iron…
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency Anemia Treatment
- Trial name
- NCT04793906
- Testing
- Iron supplement with a lunch meal containing beef, Iron supplement with a lunch meal containing plant-based alternative
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Iron Deficiency
Improving Iron Levels in Female Endurance, Intermittent, and Power/Strength Athletes Aged 16-35
The goal of this clinical trial is to learn if different types and doses of oral iron supplements can improve iron levels, athletic performance, and gut health in young female athletes with low iron stores.
- Trial name
- FeSc2 (NCT06942208)
- Testing
- Low-dose iron (ferrous sulfate), Yeast-bound iron (ferrous sulfate), High-dose iron (ferrous sulfate)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Iron Deficiency
Effects of Iron Supplementation on Skeletal Muscle Properties in Females With Suboptimal Iron Storage
The goal of this clinical trial is to learn whether oral iron supplementation will increase skeletal muscle iron storage and its effects on exercise capacity in females with suboptimal iron status.
- Trial name
- MyoIRON (NCT07084298)
- Testing
- Oral iron supplement
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Dry Eye Syndrome
Oral Nutrition Impact on Tear Film
Dry eye disease (DED) is a common but often inadequately treated disease of the tears and surface of the eye. It can cause poor vision and chronic pain and is more frequent with increasing age.
- Trial name
- ONIT (NCT01561040)
- Testing
- Omega 3, Vitamins A, D3 and E
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eye and Vision Technologies and Research Institute
Healthy
Efficacy of 3 Nutritional Supplements to Improve Diverse Outcomes in Children Under 2 Years of Age and Pregnant Women
The Mexican poverty alleviation program, Oportunidades provides a fortified food supplement to all beneficiary children under 2 years of age, and all pregnant and lactating women.
- Trial name
- NCT00531674
- Testing
- fortified milk-based beverage, Sprinkles, tablets
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mexican National Institute of Public Health
Nitric Oxide, Placebo
Impact of Beetroot Juice Ingestion on Female Rugby Performance
Rugby is a team sport characterized by high-intermittent efforts, due to the importance of realizing intermittent and explosive efforts in rugby the use of nutritional strategies such as beetroot ingestion should be explored with…
- Trial name
- BEETJUICERUGBY (NCT05209126)
- Testing
- Beetroot juice
- Where
- 2 sites in Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Ketosis, Blood Hormones
The Impact of Ketone Monoester Intake on Post-exercise Hormonal Responses After Resistance Exercise in Young Males
This study investigates how orally ingested exogenous ketone monoester supplements affect circulating hormone concentrations in healthy young adult males after a single session of resistance exercise.
- Conditions
- Ketosis, Blood Hormones, Testing Effect of Intervention, Resistance Exercise
- Trial name
- NCT06683547
- Testing
- Ketone Monoester (KET), Resistance Exercise
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- McGill University
Gestational Diabetes
Effect of Fibre Supplements on Gestational Diabetes
The primary aim of this study is to evaluate the effect of a soluble fibre supplement in the development of gestational diabetes in women at high-risk.
- Trial name
- GG-GDM (NCT03547960)
- Testing
- Guar gum, Cellulose
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Iron-deficiency, Iron Deficiency Anemia
Effects of Enhancers and Inhibitors on Absorption From Iron Supplements
Iron deficiency (ID) is a major public health problem worldwide and oral iron supplementation can be an effective strategy to treat and prevent ID.
- Trial name
- NCT05414474
- Testing
- Reference, Ascorbic acid (AA) 500 mg, Ascorbic acid (AA) 80 mg
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy Diet
Bioavailability and Pharmacodynamics of EPA and DHA From Fortified Soymilk and Capsules
This study will compare the algae oil fortified soymilk to a commercial algae oil capsule containing the same base oil with the goal of demonstrating equivalent or greater accumulation of EPA and DHA in blood lipid pools.
- Trial name
- NCT05802797
- Testing
- Algae Oil Fortified Soymilk, Algae Oil Capsule
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Healthy, No Evidence of Disease
Effects of Garlic Supplements on Opioids in Healthy Volunteers
RATIONALE: Garlic supplements may alter the pharmacokinetics of oxycodone, thereby affecting its effectiveness as an opioid analgesic for the relief of moderate or severe pain.
- Trial name
- NCT00499460
- Testing
- garlic powder tablets, oxycodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Malnutrition, Stunting
Controlled Trial to Test the Efficacy of Lipid-based Nutrient Supplements to Prevent Severe Stunting Among Infants
This study tests the hypothesis that infants receiving milk-powder containing fortified spread (lipid-based nutrient supplement) as a complementary food for one year have lower incidence of severe stunting (poor length gain) than…
- Conditions
- Malnutrition, Stunting, Developmental Delay
- Trial name
- LCNI-5 (NCT00524446)
- Testing
- Milk-containing fortified spread, Soy-containing fortified spread, Maize-soy flour
- Where
- Malawi
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Tampere University
Skeletal Muscle, Extracellular Matrix
Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men
The purpose of this study is to assess which amino acids are affecting acute muscle collagen synthesis in response to supplementation and exercise.
- Conditions
- Skeletal Muscle, Extracellular Matrix, Amino Acids Metabolism, Exercise
- Trial name
- PECS (NCT04596553)
- Testing
- Essential Amino Acid, Collagen Peptide
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Biological Availability
Bioavailability of Hydroxytyrosol From Olive Watery Extract Supplements
The aim of this cross-over study is to assess the bioavailability of hydroxytyrosol in healthy males after the intake of two olive watery extract supplements and one olive oil.
- Trial name
- NCT04876261
- Testing
- Oliphenolia® bitter, Oliphenolia®, La Vialla Extra Virgin Olive Oil containing 5 mg hydroxytyrosol
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Daacro