Clinical trials: Supplements
Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis
Plant Stanols and Liver Inflammation in Overweight and Obese Children
Obesity is associated with a variety of co-morbidities. Children with obesity are more likely to have risk factors associated with cardiovascular diseases (CVD) and CVD risk markers (e.g.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, NAFLD, NASH
- Trial name
- NCT04783116
- Testing
- Plant stanols (3g/day)
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- Maastricht University Medical Center
Lung Cancer
Efficacy and Safety of Omega 3 Fatty Acid Supplements on Heavy Smokers
The study duration is 12 months. The initial enrollment visit will take approximately one hour. The Month 1, 3, 6, 7, 9 and 12 visits will take approximately 30 minutes each.
- Trial name
- Omega (NCT03936621)
- Testing
- Omega 3 fatty acid
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Depressive Disorder, Major, Depression
The Effect of Probiotic Supplementation on the Mental Status, Inflammation, and Intestinal Barrier in Major Depressive Disorder Patients Using Gluten-free or Gluten-containing Diet
More and more evidence confirms the relationship between the gut-brain-microbiota axis and the symptoms of mood disorders. A potential pathway connecting the intestines and the brain in depression is inflammation.
- Trial name
- SANGUT (NCT03877393)
- Testing
- Probiotic supplementation + gluten-free diet, Probiotic supplementation + gluten-containing diet
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Lublin
Athletic Performance
The Effect of Alginate Encapsulated Supplements on Athletic Performance and Recovery
Endurance sport is often characterized by high training loads and significant metabolic demands, including depletion of endogenous fuel stores (e.g. liver and muscle glycogen) and damage to the skeletal muscle proteins.
- Trial name
- SWAP (NCT06165393)
- Testing
- Slow-release CHO-AA, Slow-release CHO, CHO
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Constipation, Cancer
A Study of Herbal Supplements in Cancer Survivors With Constipation
The purpose of this study is to find out whether MZRW is an effective treatment for constipation in cancer survivors. The researchers will compare MZRW with placebo, a pill that looks like MZRW and is given in the same way, but…
- Conditions
- Constipation, Cancer, Functional Constipation
- Trial name
- NCT07091084
- Testing
- MZRW
- Where
- 7 sites in United States
- Volunteers
- 70 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Healthy
Pharmacokinetics of Omega-3 Monoglycerides
North American diets have insufficient omega-3 fatty acid (n-3 FA) content. Consequently, they display low plasma concentrations of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), the two main long chain n-3 FA.
- Trial name
- NCT04382027
- Testing
- Omega-3 + vitamin K2 (monoacylglycerol form), Omega-3 + vitamin K2 (ethyl ester)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Dietary Supplements: Beetroot Juice Acute Supplementation, Dietary Supplement: Placebo Acute Supplementation
Acute Effects of Beetroot Juice Ingestion on Cognitive Function and Neuromuscular Performance in Elite Female Taekwondo Athletes
Beetroot juice is a good source of nitrate (NO3-), which is a precursor of nitric oxide (NO) through the NO3- to nitrite (NO2-) to NO pathway (Lundberg et al., 2008).
- Trial name
- BEET_TAEKWONDO (NCT06675305)
- Testing
- Beetroot juice (James White, UK)
- Where
- Spain
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Bone Resorption, Bone and Bones
Combination Plant-Based Protein and Marine-Based Multi-Mineral Supplement and Bone Remodeling in Young Adults
Nutrient intake of calcium and protein are known to function as regulators of bone remodeling. Specifically, a balanced rate of bone resorption and bone formation (i.e.
- Trial name
- NCT05533502
- Testing
- Combined Plant-Based Protein and Marine-Based Multi-Mineral Supplement
- Where
- Ireland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Alzheimer's Disease, Oxidative Stress
Fish Oil and Alpha Lipoic Acid in Treating Alzheimer's Disease
The purpose of this study is to determine the effect of fish oil and the antioxidant alpha lipoic acid on factors in the blood that are associated with the progression of Alzheimer's Disease (AD).
- Conditions
- Alzheimer's Disease, Oxidative Stress, Dementia, Hyperlipidemia
- Trial name
- NCT00090402
- Testing
- Fish Oil, Lipoic Acid
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Oregon Health and Science University
Menopause, Elevated Blood Pressure
Blueberries for Improving Vascular Endothelial Function in Postmenopausal Women With Elevated Blood Pressure
Postmenopausal women are at an increased risk of developing cardiovascular disease (CVD) largely due to accelerated aging-related modifications to vascular health following menopause.
- Conditions
- Menopause, Elevated Blood Pressure, Hypertension, Endothelial Dysfunction
- Trial name
- NCT03370991
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Colorado State University
Recovery of Hemoglobin and Iron Stores After Blood Donation
Hemoglobin and Iron Recovery Study
The purpose of this study is to investigate the effect of daily iron supplements after blood donation on time to recovery of hemoglobin and iron stores.
- Trial name
- HEIRS (NCT01555060)
- Testing
- ferrous gluconate
- Where
- 4 sites in United States
- Volunteers
- 215 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Glucose Metabolism After Transplantation
The Effect of Magnesium on Early Post-transplantation Glucose Metabolism
Hypomagnesemia is common early after transplantation, especially in association with calcineurin inhibitors and predicts diabetes after transplantation.
- Trial name
- NCT01889576
- Testing
- Magnesium Oxide
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- University Hospital, Ghent
Frail Elderly Syndrome
Management of Frailty in Older Adults With Turmeric and Tulsi Supplements
The aim of this study is to determine the efficacy of turmeric and tulsi polyherbal formulation in the management of frailty in the elderly population.
- Trial name
- NCT03365310
- Testing
- C. longa, curcuminoids , Z. officianale, O. sanctum along with 200 ml of Milk, Standard of Care
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Composite Interceptive Med Science
Exclusive Breast Feeding, Feeding Patterns
SPOON: Sustained Program for Improving Nutrition - Guatemala
The primary goal of this study is to assess the impact of an innovative strategy to prevent undernutrition and obesity in early childhood in children 0-24 months in Guatemala.
- Conditions
- Exclusive Breast Feeding, Feeding Patterns, Stunting, Obesity, Childhood
- Trial name
- NCT03399617
- Testing
- Micronutrient Powders, SPOON behavioral change strategy, SQ-LNS
- Where
- Guatemala
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- Inter-American Development Bank
Spastic Cerebral Palsy
Feasibility Nutritional Supplements for Muscle Growth in CP
The purpose of this study is to investigate the feasibility of a 10-week plan with a nutritional supplement (leucine) and to perform pilot analyses on the effect of leucine on macroscopic muscle morphology in children with…
- Trial name
- Nut-CP (NCT06044168)
- Testing
- Dietary Supplement: Leucine
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Non-verbal Learning Disorder, Autism Spectrum Disorder
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood…
- Conditions
- Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
- Trial name
- NCT03757585
- Testing
- Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Physical Exercise, Time Restricted Eating
Effect of Time-restricted Eating and Endurance Training on Markers of the Health of Women and Men
The aim of this project is to demonstrate the synergistic effect of TRE and NW training on health indicators for older women. The women will be divided into four groups, i.e.
- Conditions
- Physical Exercise, Time Restricted Eating, Mental Health Wellness 1, Wellbeing
- Trial name
- NCT05229835
- Testing
- Time restricted eating and exercise
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Cytokine Storm, Cytokines
The Effect of Omega-3 on Selected Cytokines Involved in Cytokine Storm
The trial was designed to assess the effect of daily dose of 300 mg omega-3 supplements for 2 months on the selected interleukins levels in uninfected people with Covid-19.
- Trial name
- NCT04483271
- Testing
- 300 mg of omega3-FA
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Sarcopenic Obesity
Effects of Whole-body Electromyostimulation and Dietary Supplements on "Sarcopenic Obesity"
The aim of the study is to determine the effect of whole body electromyostimulation (WB-EMS) and/or nutritional on body composition and functional tasks in elderly females with sarcopenic obesity.
- Trial name
- NCT02356016
- Testing
- WB-EMS Intervention, WB-EMS-Intervention and dietary supplementation, control (dietary counseling)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Constipation
Effects of Prebiotic or Probiotic Supplements on Symptoms of Functional Constipation
This study intends to evaluate the effects of three prebiotic solid beverages (mainly dietary fiber and prebiotics) and one probiotic solid beverage on the laxative effect of patients with functional constipation through…
- Trial name
- NCT04667884
- Testing
- Prebiotics or Probiotics
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xi'an Jiaotong University