Clinical trials: Supplements
Metabolic Health
Viome Nutritional Programs to Improve Clinical Outcomes for Metabolic Conditions
US residents who have obesity and sign the informed consent form and are screened and enrolled for this study. Participants who are enrolled complete a survey upon enrollment and are randomized into one of three arms.
- Trial name
- NCT05564273
- Testing
- VIOME Precision Nutrition Program, VIOME-designed condition-based supplements
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Viome
Frailty, Inflammation
Reducing Frailty for Older Cancer Survivors Using Supplements
The purpose of the study is to examine the feasibility and safety of twelve weeks oral supplementation of Epigallocatechin-3-gallate (EGCG) in older survivors of cancer
- Trial name
- ReFOCUS1 (NCT04553666)
- Testing
- Epigallocatechin-3-Gallate (EGCG) plus Ascorbic Acid (Vitamin C)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Rochester
Malnutrition, Diarrhea
Evaluation of Zinc and / or Micronutrient Supplementation on Intestinal Flora, Diarrheal Disease Burden, Intestinal Mucosal Integrity and Growth Among Children of Pakistan
Information on the mechanisms of zinc is still in developing phase. Ecological and biological implications of long term zinc supplementation at population level requires assessment.
- Conditions
- Malnutrition, Diarrhea, Pneumonia, Growth
- Trial name
- NCT00705445
- Testing
- Micronutrient Supplementation without Zinc, Micronutrient Supplementation with Zinc, Nutritional Counselling and Education
- Where
- 2 sites in Pakistan
- Volunteers
- 2,745 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Exercise Training, Carnosine
The Influence of Exercise on Tissue Beta-alanine Uptake and Carnosine Synthesis Rates
B-alanine supplementation is highly efficient in increasing intramuscular carnosine content, leading to improved physical performance, especially in high-intensity exercises (HIIE).
- Conditions
- Exercise Training, Carnosine, Dietary Supplements
- Trial name
- NCT04936737
- Testing
- Beta-alanine supplementation, High intensity interval exercise
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Oxidative Stress, Inflammation
Innovative Biotechnological Production of Antioxidant Products
Several natural compounds have been explored as immune-boosting, antioxidant, and anti-inflammatory dietary supplements. Amongst them, hydroxytyrosol a natural antioxidant found in olive products, and endemic medicinal plants…
- Conditions
- Oxidative Stress, Inflammation, Body Weight, Homocystine; Metabolic Disorder
- Trial name
- Antiox-Plus (NCT05679310)
- Testing
- Hydroxytyrosol/Essential oils
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Beetroot Juice, Caffeine
Acute Effects of Beetroot Juice and Caffeine Co-ingestion on Lower-limb Strength and Muscular Endurance in Females
The aim of this study is to evaluate the acute effects of beetroot juice and caffeine, consumed individually or in combination, on lower-limb strength and muscular endurance in physically active women.
- Conditions
- Beetroot Juice, Caffeine, Placebo, Beetroot Juice with Caffeine Co-ingestion
- Trial name
- NCT06758323
- Testing
- Beetroot juice combined with caffeine (COM)
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Jose Manuel Jurado Castro
Bioavailability and AUC
The Objective of This Study Was to Compare and Quantify the Bioavailability of Citrulline Byproducts in Blood Samples and in Urine Samples After a Single Dose of the Assigned Dietary Supplement. The Treatment Arms Containing the Following Molecules: Citrulline HCL and L-Citrulline,
Citrulline dietary supplements are of interest for improving cardiovascular and exercise performance. The health benefits of citrulline are attributable to its ability to increase arginine levels in the body through the…
- Trial name
- NCT06977854
- Testing
- Removal from study. In case of adverse event, subject treated for the AE., removal from study
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.
Inflammation
Effects of Dietary Supplements on Response to Air Pollution
This study will determine if a comprehensive antioxidant/anti-inflammatory dietary supplement pack can offer protection against a decline in lung function and increase in inflammation and oxidative stress following acute exposure…
- Trial name
- NCT01488656
- Testing
- Antioxidant, anti-inflammatory dietary supplement
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Utah State University
Vitamin D Deficiency
The Effect of Fat on Vitamin D Absorption
The purpose of this study is to evaluate the absorption of dietary supplement of vitamin D3 (cholecalciferol), through the variation of 25 (OH) D levels, as the fat content of the meal associated with the administration of the…
- Trial name
- VITD_100484 (NCT01519986)
- Testing
- Vitamin D3
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Hypercholesterolemia
Effect of a Treatment With a Nutraceutical Combination on Sub-optimal LDL Cholesterol Levels
High cholesterol is one of the major controllable risk factor for coronary heart disease. It is well demonstrated that drugs that reduce the intestinal absorption of cholesterol or block the synthesis of cholesterol or the…
- Trial name
- NATCOL (NCT03739242)
- Testing
- Nutraceutical combination
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- A. Menarini Industrie Farmaceutiche Riunite S.r.l.
Individual Difference, Food Sensitivity
Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Brief Summary: This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04302779
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Reading
Exogenous Ketosis
Acceptability and Tolerability of Ketone Supplements and Effects of BHB Concentrations in Young Adults
Assess the acceptability and tolerability of two different commercially available ketone supplements and determine their effects on capillary blood concentrations of the ketone beta-hydroxybutyrate and glucose in young adults.
- Trial name
- NCT05390385
- Testing
- KE1 5g, KE1 10g, KE4 5g
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Elderly
Comparison of Medical Nutritional Supplements
The objective of this study is to verify changes in protein metabolism after ingesting a oral medical nutritional supplement.
- Trial name
- NCT01483976
- Testing
- Oral medical nutritional supplement, Experimental oral medical nutritional supplement with AN777
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Aged, Healthy
New E-Service for a Dietary Approach to the Elderly
Ageing of the population is a major event in the world. Gerontological/geriatric literature unanimously indicate that physical exercise and diet are at present the two available fundamental approaches to contrast/prevent most of…
- Trial name
- RISTOMED (NCT01179789)
- Testing
- Optimal Diet, VSL#3®, AISA-5203-L
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy
Strength-enhancing Effect of Whey Protein Supplementation Following Resistance Exercise in Adolescent Males
This study investigates the strength gains associated with resistance training in a group of 18 male high school athletes consuming either a whey protein supplement or chocolate milk following their exercise.
- Trial name
- NCT02162459
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Olympia Eye Clinic
Nitric Oxide, Vascular Function
Nutritional Supplements and Nitric Oxide Bioactivity
Obese people have a disturbed postprandial metabolism and thereby a decreased postprandial vascular function. Nitric oxide plays an important role in the postprandial vascular function.
- Conditions
- Nitric Oxide, Vascular Function, L-Arginine, Nitrate / Nitrite
- Trial name
- NCT03625596
- Testing
- L-Arginine, Nitrate / Nitrite
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center