Clinical trials: Supportive Care in Cancer
Anxiety, Supportive Care in Cancer
Living Well Program: Impact on Healthcare Costs and Clinical Outcomes in Breast Cancer Care
The goal of this study is to evaluate the efficacy and cost-effectiveness of the Living Well Program, a digital therapeutic application with telecoaching support, in breast cancer patients with moderate-to-severe anxiety.
- Conditions
- Anxiety, Supportive Care in Cancer, Depression
- Trial name
- NCT07236437
- Testing
- Living Well Program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Scott A. Irwin, MD, PhD
Advanced Pancreatic Cancer
A Study of Docetaxel for Injection (Albumin Bound) in Patients With Advanced Pancreatic Cancer
This study is a randomized, double-blind, multicenter, phase Ⅲ clinical study to compare the clinical efficacy and safety of Docetaxel for Injection (Albumin Bound) in combination with best supportive care versus placebo in…
- Trial name
- NCT06492941
- Testing
- Docetaxel for Injection (Albumin bound), Best supportive care
- Volunteers
- 142 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Colorectal Cancer
Durvalumab and Tremelimumab and Best Supportive Care vs Best Supportive Care in Patients With Advanced Colorectal Cancer
The standard or usual treatment for this disease is treatment with drugs and other treatments that may help to make a patient better or may improve their quality of life. This treatment is known as "best supportive care" (BSC).
- Trial name
- NCT02870920
- Testing
- Tremelimumab, Durvalumab, Best Supportive Care
- Where
- 25 sites in Canada
- Volunteers
- 180 people
- Sponsor
- Canadian Cancer Trials Group
Advanced Neuroendocrine Tumors of Pancreatic Origin
Efficacy and Safety of Everolimus (RAD001) Compared to Placebo in Patients With Advanced Neuroendocrine Tumors
The purpose of this study was to evaluate progression free survival in those participants assigned everolimus 10 mg/day plus Best Supportive Care versus those assigned to placebo plus Best Supportive Care in Advanced…
- Trial name
- RADIANT-3 (NCT00510068)
- Testing
- Everolimus
- Where
- 82 sites in United States, Belgium and 16 more
- Volunteers
- 410 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer, Leukemia
Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer
RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy.
- Conditions
- Breast Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00006225
- Testing
- filgrastim, recombinant flt3 ligand, recombinant human thrombopoietin
- Where
- United States
- Sponsor
- Northwestern University
Neoplasm, Colorectal, Cognitive Impairment
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute.
- Conditions
- Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change
- Trial name
- Chemo Brain (NCT05014399)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph McCollom
Head &Amp;Amp; Neck Squamous Cell Carcinoma
The FORCE Trial Pilot: Fish Oil-enriched Nutrition for Radiotherapy in Cancer of the hEad and Neck
en-label, proof-of-concept study designed to evaluate the feasibility, safety, and acceptability of a prophylactic fish oil-enriched nutritional supplement (Fresubin Supportan) in patients with head and neck cancer (HNC)…
- Trial name
- FORCE (NCT07180576)
- Testing
- Nutrition counseling, Fresubin Supportan
- Volunteers
- 15 people
- Sponsor
- Anna Arthur, PhD
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial
This clinical trial evaluates whether geriatric assessment-driven interventions with supportive care (GAIN-S) using telemedicine can be used to identify areas of vulnerability (weakness) in older adults with cancer and guide…
- Trial name
- NCT06022965
- Testing
- Best Practice, Comprehensive Geriatric Assessment, Electronic Health Record Review
- Where
- 3 sites in United States
- Volunteers
- 216 people
- Sponsor
- City of Hope Medical Center
Carcinoma, Non-Small-Cell Lung
BIBW 2992 and BSC Versus Placebo and BSC in Non-small Cell Lung Cancer Patients Failing Erlotinib or Gefitinib (LUX-LUNG 1)
This randomized, double-blind, multi-center Phase IIb/III trial will be performed in patients with NSCLC who have received previous treatment with at least one but not more than two lines of cytotoxic chemotherapy (one line must…
- Trial name
- NCT00656136
- Testing
- BIBW 2992
- Where
- 90 sites in United States, Belgium and 13 more
- Volunteers
- 585 people
- Sponsor
- Boehringer Ingelheim
Leukemia
Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
RATIONALE: Monoclonal antibodies such as gemtuzumab ozogamicin can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells.
- Trial name
- AML-19 (NCT00091234)
- Testing
- gemtuzumab ozogamicin
- Where
- 45 sites in Belgium, Italy and 1 more
- Volunteers
- 279 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Cancer, Geriatric Syndrome
Risk-Based Geriatric Assessment-Driven Management in Older Patients Starting Chemotherapy
Older patients with cancer are at increased risk of severe chemotherapy-related toxicities due to comorbidities, functional impairments, and geriatric syndromes.
- Conditions
- Cancer, Geriatric Syndrome, Frailty, Chemotherapy Toxicity
- Trial name
- NCT07485634
- Testing
- Geriatric Assessment-Driven Management Algorithm (GA-MA)
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- The University of Hong Kong
Radiation Therapy, Metastatic Cancer
Assessment of Early Radiation Oncology Involvement Alongside Standard Oncologic Care in the Managemet
To determine if the experimental approach of early radiation oncology involvement alongside standard oncologic care will result in higher HRQL at 6 months compared to the control arm receiving standard oncologic care alone, based…
- Trial name
- NCT05351294
- Testing
- Questionnaires, Early Radiation Oncology Involvement Alongside Standard Oncologic Care
- Where
- 6 sites in United States
- Volunteers
- 156 people
- Sponsor
- Rutgers, The State University of New Jersey
Penile Cancer
A PHASE II, RANDOMIZED STUDY TO ASSESS MAINTENANCE THERAPY WITH CEMIPLIMAB VERSUS BEST SUPPORTIVE CARE AFTER 1ST LINE PLATINUM-BASED CHEMOTHERAPY IN ADVANCED/RECURRENT PENILE CANCER
This is a phase II, randomized study which will enroll participants given 4 to 6 cycles of first-line platinum-based chemotherapy treatment for advanced penile SCC not amenable by curative surgical treatment (stages III-IV as per…
- Trial name
- BRAVA PENILE (NCT07101822)
- Testing
- Cemiplimab
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Hospital Israelita Albert Einstein
Cancer, HIV
Improving Engagement in HIV and Cancer Care in Zimbabwe
In Zimbabwe, people who have cancer and HIV may have a difficult time staying engaged in their HIV care while they are being treated for cancer.
- Trial name
- NCT06934369
- Testing
- Strategies to improve HIV care engagement
- Where
- Zimbabwe
- Volunteers
- 300 people
- Sponsor
- Fred Hutchinson Cancer Center
Oncology, Aerodigestive Tract Cancer
Impact of Adapted Aesthetic Onco in Patients With Upper Aerodigestive Tract Cancer During Their Management
Treatment for cancers of the pharyngolarynx is mutilating, with major consequences for patients' lives in terms of physical and functional after-effects.
- Conditions
- Oncology, Aerodigestive Tract Cancer, Suportive Care
- Trial name
- OEUVRE (NCT06959810)
- Testing
- Adapted Onco-Esthetics sessions
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Centre Francois Baclesse
Breast Cancer
The Effect of Training Given by Mobile Application to Women Undergoing Breast Surgery
In a metanalysis study examining the effects of mobile health applications on the quality of life and psychological outcomes of patients with breast cancer, it was concluded that the quality of life increased, the level of…
- Trial name
- NCT04914780
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- KTO Karatay University
Prostate Cancer Patients, Sexual Dysfunctions
Dyadic STEP-SexPCare for Sexual Health in Chinese Prostate Cancer Survivors and Their Female Partners
This pilot feasibility randomized controlled trial will evaluate the feasibility, acceptability, safety, and preliminary effects of Dyadic STEP-SexPCare, a culturally tailored, nurse-led psychosexual programme for Hong Kong…
- Trial name
- STEP-SexPCare (NCT07829367)
- Testing
- Dyadic STEP-SexPCare, Standard Survivorship Care
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Musculoskeletal Pain
Efficacy of Cryotherapy Combined or Not With Analgesics in Uncontrolled Painful Musculoskeletal Metastasis
The primary objective of this trial is to compare the efficacy of 2 analgesic strategies, based on percutaneous cryotherapy plus medical supportive care versus medical supportive care alone in the treatment of cancer patients…
- Trial name
- CRYO (NCT03441139)
- Testing
- Cryotherapy + Medical analgesics, Medical Analgesics
- Where
- 8 sites in France
- Volunteers
- 18 people
- Sponsor
- Centre Leon Berard
Oral Mucositis, Total Body Irradiation
Chlorophyllin for Reducing Oral Mucositis in Total Body Irradiation Prior to Transplant
The goal of this phase II, single-arm interventional clinical trial is to evaluate whether oral sodium copper chlorophyllin (CHL) can reduce the frequency and severity of oral mucositis in patients aged 12-65 years undergoing…
- Conditions
- Oral Mucositis, Total Body Irradiation, Hematological Malignancies, Hematopoietic Stem Cell Transplantation (HSCT)
- Trial name
- ChROMME-TBI (NCT07709195)
- Testing
- Sodium Copper Chlorophyllin
- Where
- India
- Volunteers
- 17 people
- Sponsor
- Tata Memorial Centre
Neoplasm of Breast
Therapeutic Education and Nursing Support Program for Supportive Care, in Patients Treated With Hormone Therapy for Non-metastatic Breast Cancer
To compare the efficacy of the addition of a therapeutic education program combined with nursing phone follow-up, compared to conventional management alone, on the management of adverse events (AEs) related to adjuvant hormone…
- Trial name
- ETAPH (NCT04794075)
- Testing
- Therapeutic Education and Nursing Support Program for Supportive Care
- Where
- 9 sites in France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Emile Roux