Clinical trials: Supportive Therapy
Depression
Telephone Support vs. Self-guidance in an Internet-based Self-administered Psychological Program to Address Depression
Depression is a first level problem that poses a challenge for Primary Care (PC). The overload of care in this area requires lower-cost and more accessible alternatives.
- Trial name
- NCT06230237
- Testing
- Smiling is fun + professional support, Smiling is fun
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Tobacco Smoking, Second Hand Tobacco Smoke
eCEASE to Support Treatment for Parental Tobacco Use
The proposed project aims to develop an innovative and disseminable electronic health record (iEHR)-based approach that supports optimal primary care workflows to routinely screen families for tobacco and e-cigarette use, address…
- Conditions
- Tobacco Smoking, Second Hand Tobacco Smoke, Smoking Cessation
- Trial name
- eCEASE (NCT04974736)
- Testing
- iEHR + Navigator
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Opioid Use Disorder, Peer Recovery Supporters
Peer Recovery Support for Opioid Use Disorder Treatment Retention
The goal of this clinical trial is to learn whether adding peer recovery support services to standard opioid use disorder (OUD) treatment in primary care helps patients stay in treatment longer.
- Conditions
- Opioid Use Disorder, Peer Recovery Supporters, Peer Recovery Coaching, Primary Care
- Trial name
- NCT07620171
- Testing
- Peer Support
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
This Study Focus on the Effect of Low-Level Light Therapy on the Amount of Upper Molar Distalization
Assessment of Low Level Laser Therapy Effect on Treatment Outcomes of Bony Supported Distal Jet for Correction of Angle Class II Malocclusion (Randomized Clinical Trial)
The goal of this randomized clinical trial is to compare the effect of LLLT in adolescent patient with class II malocclusion. The main question it aims to answer is: is there a difference in the amount of distalization between…
- Trial name
- LLLT (NCT06170099)
- Testing
- low level laser therapy, bonny supported distal jet
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Dementia, Mild Cognitive Impairment
A Pilot Study for the Brain Health Support Program
Prior studies have shown that programs that focus on promoting brain health and managing lifestyle risks (such as poor diet, obesity, physical inactivity, sleep issues, loneliness) may help in preventing or lowering the risk of…
- Conditions
- Dementia, Mild Cognitive Impairment, Subjective Cognitive Impairment, Pre-dementia
- Trial name
- CTU BHSP-P (NCT05167045)
- Testing
- Brain Health PRO
- Where
- 3 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baycrest
Treatment Adherence
Pilot Evaluation of Peer-support Coaching to Increase Adherence to Online Self-help for College Mental Health
This study aims to test if coaching can improve program adherence to an online mental health program in college students if delivered by undergraduate peers.
- Trial name
- NCT04573465
- Testing
- Phone Coaching, Text Message Coaching, ACT Guide
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Utah State University
Tobacco Use Cessation
Improving Quitline Support Study
This study seeks to evaluate ways to improve outcomes for low-education, uninsured or Medicaid-eligible smokers who do not successfully quit with standard telephone quit line treatment.
- Trial name
- IQS (NCT03538938)
- Testing
- 1-Call Quitline Counseling, 4-Call Quitline Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 1,316 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Periodontal Diseases
Lactobacillus Reuteri in the Supportive Therapy of Periodontitis
Literature shows the potential effectiveness of L. reuteri as an adjunct to non-surgical periodontal therapy in initial treatment of periodontitis, but also underlines the limits of the conclusions, and the heterogeneity and…
- Trial name
- PERIOPRO (NCT04478643)
- Testing
- Probiotic: Lactobacillus Reuteri
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Smoking Prevention
Digital Health Game as an Intervention Supporting Tobacco-related Health Literacy in Early Adolescents
This feasibility study evaluates acceptability and preliminary effectiveness of a digital health game as an intervention supporting tobacco-related health literacy in 10- to 13-year-old early adolescents.
- Trial name
- NCT02717910
- Testing
- Health game, Web page
- Where
- Finland
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Turku
Type 1 Diabetes
REAL-Fam Feasibility Study for Youth Diabetes Management
The goal of this clinical trial is to learn if the REAL-Fam occupational therapy intervention is feasible to study in a larger-scale randomized controlled trial.
- Trial name
- NCT07212790
- Testing
- REAL-Fam Occupational Therapy Family Coaching
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Human Immunodeficiency Virus (HIV)
ComBaCaL HIV Prevention TwiCs
This cluster-randomized intervention is embedded in the ComBaCaL (Community-Based Chronic disease care Lesotho) cohort study (EKNZ ID AO_2022-00058, clinicaltrials.gov ID NCT05596773, Lesotho NH-REC ID 210-2022), a platform for…
- Trial name
- CoPrev (NCT07581600)
- Testing
- CoPrev model, Referral to the nearest responsible health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Alcohol Use Disorder
Supporting Adolescent Alcohol Treatment With Computer-Based ('Path180') Skills Training
This 8-week clinical trial will test a computer-based skills training program called Path180 with 112 adolescents aged 13 to 19 who are receiving mental health counseling or outpatient substance use treatment.
- Trial name
- NCT07713251
- Testing
- Path180
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Brown University
Development Delay, Neurodevelopmental Disorders
Translating Peer-to-Peer Support Into a Clinical Setting
There is not a lot of research focusing on Black and African American families raising young children with developmental delays.
- Conditions
- Development Delay, Neurodevelopmental Disorders, Autism
- Trial name
- NCT04313283
- Testing
- Parents Taking Action
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV/AIDS
Video-Intervention to Inspire Treatment Adherence for Life for Adolescents
This a two-arm randomized controlled trial whose objective is to explore the impact of VITAL Start for Adolescents (VS4A), a video-based antiretroviral treatment (ART) adherence intervention, on a range of implementation and…
- Trial name
- VS4A (NCT07064785)
- Testing
- Video-based ART adherence counseling, Standard of Care (SOC)
- Where
- 32 sites in Malawi
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Opioid Use Disorder, Treatment Adherence
Digital Health Intervention to Support Opioid Use Disorder Treatment
In prior studies, the investigative team developed a combined computer- and text message-delivered personalized-feedback intervention (iENDURE) designed to enhance motivation and improve tolerance of distress to support the early…
- Trial name
- iENDURE (NCT03842384)
- Testing
- iENDURE
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Supportive Care
The Effect of Care Based on the Salutogenesis Model
On the basis of the Salutogenesis Model, this study is based on the development of individuals' internal and external resources for game addictions and strengthening their sense of integrity.
- Trial name
- NCT06767826
- Testing
- Salutogenesis Models
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Breast Cancer
Hyperventilation and Oxygenation to Prolong Breath Hold in Breast Cancer Irradiation Treatment
With the HOBBIT trial, the investigators want to develop a technology that allows volunteers to hold their breath for a long time.
- Trial name
- HOBBIT (NCT04091542)
- Testing
- Optiflow/Ventilator
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Community Reinforcement And Family Training, Family Health
We The Village Family Support Study
The United States is in the midst of an opioid crisis. Over-prescription of opioid analgesic pain relievers contributed to a rapid escalation of use and misuse of these substances across the country.
- Conditions
- Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
- Trial name
- NCT04250077
- Testing
- Community Reinforcement And Family Training (CRAFT), We The Village Peer Community Forum
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- We The Village, Inc.
Depressive Disorder, Major
Can the Memory Support Intervention Improve Depression Outcome Following Cognitive Therapy?
The aim of this study protocol is to conduct a confirmatory efficacy trial to test whether the Memory Support Intervention improves illness course and functional outcomes in major depressive disorder (MDD) and cognitive therapy…
- Trial name
- NCT02938559
- Testing
- Cognitive Therapy (CT) for depression, Cognitive Therapy (CT) for depression + Memory Support
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley