Clinical trials: Supportive Therapy
Adherence, Medication, Smartphone Application
Effectiveness of Smartphone Application for Adherence Support (Vuka+)
This is a Type I Hybrid effectiveness-implementation trial to evaluate an HIV Pre-Exposure Prophylaxis (PrEP) medication adherence, persistence and social support app (Vuka+) for adolescent girls and young women (AGYW) in South…
- Trial name
- NCT06897059
- Testing
- Vuka+ application
- Where
- South Africa
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Stroke
Internally Versus Externally Guided Body Weight-Supported Treadmill Training (BWSTT) for Locomotor Recovery Post-stroke
The overriding goal of this proposal is to identify the critical physiological and biomechanical effects of BWSTT for promoting improved locomotor function in persons with post-stroke hemiparesis.
- Trial name
- NCT00125619
- Testing
- Locomotor training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Electronic Health Records
VA Integrated Medication Manager
The purpose of this study is to advance the science of healthcare informatics and to improve medication management through the development of a new approach to the electronic medical record called the Integrated Medication…
- Trial name
- IMM (NCT01787175)
- Testing
- Integrated Medication Manager
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Utah
Erectile Dysfunction
The Effects of a Nitrate Supplementation on Erectile Function
Twenty (20) individuals to be recruited from Ballantyne Medical Associates in Charlotte, NC, without any significant chronic medical history. These patients are general patients for primary care that meet inclusion criteria.
- Trial name
- NCT06213077
- Testing
- Nitric Oxide, Tadalafil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RHA Investments Ltd
Posttraumatic Stress Disorder
Assessing and Enhancing Social Support
Posttraumatic stress disorder (PTSD) is a common and impairing problem among Veterans, many of whom first seek treatment in primary care settings. PTSD is linked to reduced quality of life and increased rates of suicide.
- Trial name
- NCT05187156
- Testing
- Behavioral Activation and Social Engagement, Treatment as usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Caregiver, Malignant Neoplasm
Comic Art Creation as Supportive Care in Cancer Patients and Caregivers
This pilot clinical trial studies how well comic art creation works as supportive care in cancer patients and caregivers. Participating in a comic art creation workshop may help patients and their family members or friends share…
- Trial name
- NCT03067766
- Testing
- Art Therapy, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Diabetes Mellitus, Type 2, Diabetic Complication
mHealth Titration and Management
The principal objective of this application is to improve glycemic control of diabetic patients treated with basal insulin through use of an innovative, FDA-cleared smartphone-based insulin titration application connected to…
- Trial name
- NCT03908762
- Testing
- iSage App with connected glucometer, Magnet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amalgam Rx, Inc.
Coronavirus Disease 2019 Infectious Disease (COVID-19 Infection)
Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19
This project investigates individual treatments using convalescent severe acute respiratory Syndrome Coronavirus 2 (SARS-CoV-2) plasma in SARS-CoV-2 infected patients at risk for disease progression.
- Trial name
- NCT04389944
- Testing
- convalescent plasma application to SARS-CoV-2 infected patients
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Head and Neck Cancer
CONNECTing Head and Neck Caregivers to Supportive Care Resources
The purpose of this research is to determine feasibility and acceptability of randomized pilot trial to evaluate a technology-based intervention (CONNECT) to empower and educate caregivers about the benefits of supportive care…
- Trial name
- CONNECT-HNC (NCT03875885)
- Testing
- CONNECT, CONTROL
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Fracture Treatment
Treatment of Distal Radius Buckle Fractures
This study determines if patients with buckle fractures of the distal radius and/or ulna treated with supportive care only demonstrate non-inferior outcomes in regard to pain control during healing, functional outcome at the…
- Trial name
- NCT01762605
- Testing
- Supportive Care, Cast
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
HIV Infections
An Enhanced Adherence Support Programme for Highly Active Antiretroviral Therapy (HAART)
In southern Africa, TB is the most common first AIDS-defining condition. Initiating Antiretroviral therapy (ART) in HIV positive TB patients will lead to the inclusion of the majority of HIV/AIDS patients currently fulfilling the…
- Trial name
- eASP (NCT00408642)
- Testing
- Enhanced adherence support, Standard adherence support
- Where
- South Africa
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
HIV Prevention, HIV Risk
Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation
The goal of this study is to test if a Digital PrEP Toolkit helps cisgender women learn about and access PrEP in Alabama and Mississippi. PrEP is a medication that prevents HIV infection.
- Conditions
- HIV Prevention, HIV Risk, Sexual and Reproductive Health
- Trial name
- NCT07292584
- Testing
- Interactive Digital PrEP Toolkit
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Geriatric, Aerobic Exercise
Comparing Music-Supported and Traditional Aerobic Training in Geriatric Health Outcomes
The aim of this study is to comparatively evaluate the effects of a music therapy-based aerobic exercise program and traditional aerobic exercise training on cardiopulmonary functions, functional capacity, balance, peripheral…
- Conditions
- Geriatric, Aerobic Exercise, Music Therapy, Physiotherapy and Rehabilitation
- Trial name
- NCT06980311
- Testing
- Aerobic Exercise, Aerobic exercise with music therapy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Covid19 Vaccination, Vaccine Uptake
Supporting Audit and Feedback to Encourage Vaccine Uptake
In Ontario, approximately 6,000 family physicians can access a secure online system that provides a report that lists the COVID-19 vaccination status for each patient in their roster.
- Trial name
- NCT05099497
- Testing
- Using Practice Facilitators to Support Physicians
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Major Depressive Disorder
Deplin® P.L.U.S. Program (Progress Through Learning Understanding & Support)
This study will be an observational study in which patients who have been prescribed Deplin® are invited to participate in surveys regarding their experiences with Deplin®.
- Trial name
- NCT01369030
- Testing
- Deplin®
- Where
- 2 sites in United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
Pediatric Obesity
Reinforced Enhanced - Families Responsibility Education Support and Health
The purpose of this application is to evaluate whether a pediatric weight control program that incorporates comprehensive parenting training with behavioral therapy can increase weight loss in children compared to traditional…
- Trial name
- Re-FRESH (NCT02976636)
- Testing
- Family-based behavioral therapy, Parenting training
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Depressive Symptoms
Collaborative Stepped-Care and Productive Ageing Program for Older People With Depressive Symptoms
The Jockey Club Holistic Support Project for Elderly Mental Wellness (JC JoyAge) has developed and implemented a collaborative stepped care model for older persons at-risk of or with depression in four districts in Hong Kong…
- Trial name
- JCJoyAge2 (NCT04863300)
- Testing
- Collaborative stepped care and peer support
- Where
- 43 sites in Hong Kong
- Volunteers
- 5,239 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Primary Prevention, Healthy Aging
Personalized Disease Prevention
This study will evaluate whether patients and their providers benefit from an evidence-based decision tool to help prioritize preventive (and select chronic disease management) services based on their potential to improve…
- Conditions
- Primary Prevention, Healthy Aging, Quality of Life, Decision Support Techniques
- Trial name
- PDP (NCT05463887)
- Testing
- Individualized preventive care recommendations (decision tool)
- Where
- United States
- Volunteers
- 721 people, healthy volunteers welcome
- Sponsor
- Glen Taksler
Physiological Conditions, Distress, Emotional
Hand in Hand: Feasibility of a Compassion-Focused App to Support Parents of Children With Mental Health Problems
Parents of children and adolescents with mental health problems may experience substantial caregiving burden and emotional distress, including persistent stress, self-criticism, shame, and parental burnout.
- Conditions
- Physiological Conditions, Distress, Emotional, Caregiving Stress, Burnout
- Trial name
- NCT07840404
- Testing
- App-based Compassion Program
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Bacterial Vaginoses
Therapeutic Lactose to Support Vaginal Microbiota
The aim of the study was to investigate whether the administration of a vaginal tablet containing lactose can modulate the bacterial flora of women with bacterial vaginosis (BV).
- Trial name
- NCT03878511
- Testing
- Lactose
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan