Clinical trials: Supportive Therapy
Metabolic Dysfunction-Associated Steatotic Liver Disease
Using Digital Twin Technology and Clinical Decision Support Systems to Improve the Early Detection, Personalised Treatment, and Long-term Monitoring of Patients Across the Full Spectrum of Metabolic-associated Fatty Liver Disease (MAFLD).
The goal of this observational study is to create a detailed virtual model to better understand how Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) develops.
- Trial name
- ARTEMIS (NCT07430501)
- Testing
- Data recollection
- Where
- Spain
- Volunteers
- 7,720 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Appetitive Aggression, Post-traumatic Stress Disorder
Intervention to Support the Reintegration of Former Combatants and Soldiers
The project aims to investigate if trauma-related disorders and appetitive aggression can be reduced in former ex-combatants in DR Congo when a specific intervention (Narrative Exposure Therapy for Forensic Offender…
- Trial name
- NCT01624987
- Testing
- NET for Forensic Offender Rehabilitation (FORNET): a variant of Narrative Exposure Therapy, Control group
- Where
- Republic of the Congo
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Healthy Volunteer Study
Smart Blister Packaging and Mobile Application to Monitor and Support Medication Adherence: a Two-arm Usability Study
Many people struggle to take their medications as prescribed, which can lead to poor health outcomes and increased healthcare costs.
- Trial name
- SMART-BLISTER (NCT07099612)
- Testing
- MEMS® Mobile smartphone application, Cere®Pak smart blister pack
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Type 1 Diabetes
REAL-Fam Feasibility Study for Youth Diabetes Management
The goal of this clinical trial is to learn if the REAL-Fam occupational therapy intervention is feasible to study in a larger-scale randomized controlled trial.
- Trial name
- NCT07212790
- Testing
- REAL-Fam Occupational Therapy Family Coaching
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV (Human Immunodeficiency Virus), Clinical Decision Support System (CDSS)
Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization
This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients.
- Conditions
- HIV (Human Immunodeficiency Virus), Clinical Decision Support System (CDSS), Antiretroviral Therapy, Highly Active, INDIVIDUALIZED THERAPY
- Trial name
- NCT07219862
- Testing
- smART (Smart Antiretroviral Therapy Assistant), Traditional Prescribing resources
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Keck School of Medicine of USC
Autism Spectrum Disorder
App for Strengthening Services In Specialized Therapeutic Support
In partnership with a digital health software company, the University research team created two versions of a mobile application to help behavioral health technicians (BHT's) who work with students with autism collect data.
- Trial name
- ASSISTS (NCT05207956)
- Testing
- Behavioral economics strategies, Electronic platform
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Loneliness, Aging
The Complementary Contributions of Sensory Stimulation and Social Support During Snoezelen Room Therapy on the General Physical and Emotional Health of the Elderly Population: Optimization of the Nursing Home Resources.
Over time, lifespan is extending, the population is aging, and accordingly there is a great demand for hospital beds in nursing homes, increasing attention to this population and the services they receive.
- Trial name
- NCT05394389
- Testing
- sensory stimulating therapy, social support
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pavel Goldstein
Group Meetings
Feasibility of Therapy Integrating Peer-sharing, Technology, Aerobic and Resistance Training (TIPSTART)
The purpose of this randomized controlled clinical trial with first-generation college students with symptoms of mental illness is to test the preliminary feasibility and efficacy of TIPSTART, a multi-faceted, mental health and…
- Trial name
- TIPSTART (NCT04813198)
- Testing
- TIPSTART
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Level of Digital Game Addiction, Level of Cyberbullying
Digital Game Addiction and Cyberbullying in Adolescents
With the widespread use of technology and internet, digital game addiction and cyberbullying behaviors have increased among adolescents. Effective interventions are needed to prevent these behaviors.
- Trial name
- NCT06241989
- Testing
- health education supported by motivational interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Vaccine Knowledge, Vaccine Hesitancy
Supporting CHWs as Vaccine Educators: Impact of a Digital Training and Chatbot Intervention on Vaccination in Kenya
This study seeks to understand how to support community health workers (CHWs) to improve routine vaccination rates in high-need areas by testing a two-part intervention.
- Conditions
- Vaccine Knowledge, Vaccine Hesitancy, Vaccine Refusal
- Trial name
- NCT06237374
- Testing
- Digital Vaccine Education Training & Patient-facing Chatbot Tool, Standard Training
- Where
- Kenya
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Stanford University
HIV-1-infection, Antenatal Care
An Integrated Strategy to Support Antiretroviral Therapy and Pre-exposure Prophylaxis Adherence for HIV Prevention in Pregnant and Breastfeeding Women
This study is composed of two parallel, pilot randomized groups that will obtain preliminary data about the the acceptability, fidelity, and clinical outcomes associated with a multi-component adherence support strategy for HIV…
- Trial name
- NCT04330989
- Testing
- iNSC and Adherence supporter training
- Where
- Malawi
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
COVID-19 Respiratory Infection
Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome
Our hypothesis - that 21 days of mountain spa rehabilitation with ubiquinol supplementation could to accelerate regeneration of patients with post-COVID-19 syndrome, based on the improving platelet mitochondrial bioenergetic…
- Trial name
- SpaCOVID (NCT05178225)
- Testing
- ubiquinol (reduced coenzyme Q10), mountain spa rehabilitation, 2x14 ml of peripheral blood collected in a tube with anticoagulant
- Where
- Slovakia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Comenius University
Carcinoma In Situ, Current Smoker
Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices
This phase II trial studies how well smoking cessation treatment plans work in tobacco-dependent cancer patients when delivered virtually as part of their cancer care in community oncology practices.
- Conditions
- Carcinoma In Situ, Current Smoker, Malignant Neoplasm, Primary Neoplasm
- Trial name
- NCT03808818
- Testing
- Behavioral, Psychological or Informational Intervention, Nicotine Replacement, Quality-of-Life Assessment
- Where
- 42 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Patient Adherence
Patient Adherence to a Physical Activity Advice
Low back pain is worldwide a common musculoskeletal condition with a high number of recurrences. Recurrence rate and the number of recurrences could be reduced and time to a next episode could be prolonged by advising an active…
- Trial name
- PAPA (NCT02996955)
- Testing
- social support, treatment of illness perceptions, Activ8
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Multiple Chronic Conditions
Digitally Supported Person-centered Care Systems
The case history of patients with complex and long-term needs is often stored in fragments across many different care providers, each with a separate electronic health record.
- Trial name
- DignityCare (NCT07142616)
- Testing
- 03 - Summaries of and clinical notes from several providers, 01 - Clinical notes from one provider, 02 - Access to notes from primary and secondary care
- Where
- Norway
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Opioid Use Disorder, Treatment Adherence
Digital Health Intervention to Support Opioid Use Disorder Treatment
In prior studies, the investigative team developed a combined computer- and text message-delivered personalized-feedback intervention (iENDURE) designed to enhance motivation and improve tolerance of distress to support the early…
- Trial name
- iENDURE (NCT03842384)
- Testing
- iENDURE
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Cancer, Supportive Care
Supportive Care Delivered by Telemedicine to Cancer Patients at Home
This study will test whether supportive care follow-up delivered to cancer patients at home by telemedicine ("virtual" medical visits using telecommunications technologies) is as effective as in-person supportive care visits in…
- Trial name
- NCT04136340
- Testing
- In-person in clinic follow-up visit, Telemedicine follow-up visit
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
End-of-life Care
A Novel Mindful-Compassion Art Therapy (MCAT) Supervision
Background: The need for empathy and the difficulties of coping with morality when caring for the dying and the bereaved pose great psychological and spiritual strains.
- Trial name
- MCAT (NCT03440606)
- Testing
- Mindful-Compassion Art Therapy Supervision
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Breast Cancer, Mindfulness
Supporting Women With Breast Cancer to Prepare for Treatment (The Prepare Study)
The purpose of this study is to evaluate if a brief mindfulness intervention before and after surgery would impact patient emotional wellbeing, quality of life, and biomarkers measured before and after surgery by finger prick…
- Trial name
- Prepare (NCT07221071)
- Testing
- Mindfulness Arm
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Oncology Nurse, Psychological Support
The Impact of Multimedia Psychological Support Platform and Acceptance and Commitment Therapy Workshops of Oncology Nurses
Based on the high levels of emotional distress, burnout, and turnover intentions among clinical oncology nursing staff, this study will provide a multimedia "Mind-Body Support" Line platform and ACT workshop courses as…
- Conditions
- Oncology Nurse, Psychological Support, Acceptance and Commitment Therapy
- Trial name
- NCT06789926
- Testing
- Intervention Group
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital