Clinical trials: Supportive Therapy
Nurse-led Supportive Care
Effects of Nurse-led Supportive Care Programme on Caregiver Burden and Resilience of Family Caregivers
Lung cancer is the leading cause of cancer-related deaths worldwide, with a mortality rate of 18%. The prognosis of lung cancer is progressive and devastating, which may cause patients to experience problems during the treatment…
- Trial name
- NCT06204289
- Testing
- Nurse-led Supportive Care Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Renal Cell Carcinoma, Hepatocellular Carcinoma
A Social Support Intervention to Improve Treatment Among Hispanic Kidney and Liver Cancer Patients in Arizona
This project will develop and pilot test social support intervention for an underserved population, Hispanics in Arizona, who have high rates of kidney and liver cancer to improve health equity.
- Trial name
- NCT05418387
- Testing
- Social Support Network Intervention, Control (Patient Navigation Service)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Urinary Incontinence, Urinary Incontinence, Stress
Elastographic Assessment of Suburethral Tissue in Continent and Incontinent Women
Strain elastography (SE) will be utilized as a non-invasive imaging technique to evaluate tissue elasticity and biomechanical properties in women with stress urinary incontinence (SUI) and in continent controls.
- Conditions
- Urinary Incontinence, Urinary Incontinence, Stress, Urinary Incontinence (UI), Urinary Bladder, Overactive
- Trial name
- SE-inc1 (NCT06933407)
- Testing
- Strain Elastography
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Szeged University
Medication Abuse, Harm Reduction
Clinical Decision Support to Increase Use of Medications for Opioid Use Disorder
The objective of this study is to evaluate the impact of clinical decision support (CDS) in the form of an alert to identify patients who may be at risk of opioid use disorder (OUD) and a clinical care pathway helping providers…
- Conditions
- Medication Abuse, Harm Reduction, Opioid Use Disorder, Supportive Care
- Trial name
- NCT06526286
- Testing
- Medications for Opioid Use Disorder Pathway Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Rehabilitation, Stroke
Nature-based Therapies in Stroke Rehabilitation
Stroke rehabilitation patients are subjected to additional nature-based therapies during a rehabilitation ward period.
- Trial name
- NCT05898542
- Testing
- Nature-based therapy
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Carers, Palliative Care
A Pilot Effectiveness and Implementation Trial of CSNAT-I in Hong Kong
In this hybrid Type 1 effectiveness-implementation pilot randomized controlled trial, 60 caregivers will be randomized into either the CSNAT-I group or usual care.
- Conditions
- Carers, Palliative Care, Needs Assessment, Supportive Care
- Trial name
- NCT07193433
- Testing
- CSNAT-I
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Vaccine Hesitancy, Vaccine Refusal
Improving Vaccine Acceptance Through EHR Integrated Patient- and Provider-Facing Decision Support
The goal of this project is to establish the technical feasibility of a scalable, integrated platform to improve patient informed decision-making and increase vaccine uptake and to evaluate the effectiveness of the integrated…
- Trial name
- NCT06482450
- Testing
- LetsTalkShots (patient-facing CDS), LetsTalkShots (provider-facing CDS), Appointment Reminder Message
- Where
- United States
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Food Insecurity, Caregivers
CommunityRx for Hunger: A Hospital-Based Intervention
The goal of this research program is to reduce health disparities by deploying an information-based intervention to increase caregiver utilization of community-based food supports and satisfaction with care among food insecure…
- Conditions
- Food Insecurity, Caregivers, Clinical Trial, Hunger
- Trial name
- NCT03173794
- Testing
- CommunityRx-H
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Complication of Transplant
Supportive Care Intervention In Patients Hospitalized For Hematopoietic Stem Cell Transplantation (Shield)
The main purpose of this study is to assess whether early integration of palliative and supportive care services in care of patients hospitalized for hematopoietic stem cell transplantation (HSCT) can improve patients' and family…
- Trial name
- SHIELD (NCT02207322)
- Testing
- transplant with early palliative care
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer
An Internet-based Psychosexual Intervention for Couples Following Treatment for Breast Cancer
Diagnosis and treatment of breast cancer often leads to lower levels of sexual desire, decreased sexual arousal, painful intercourse, and difficulties achieving orgasm, and thus adversely impacts sexual functioning and intimacy.
- Trial name
- IPSIC (NCT01881022)
- Testing
- Psychosexual Intervention
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
The Study Goal is to Assess the Introduction of Sustainable Family Planning/Reproductive Health Information and Services Through, Land O' Lakes-supported Dairy Cooperatives
Family Planning Through Dairy Cooperatives
This observational study will assess a model for providing family planning through quarterly events organized by dairy cooperatives supported by Land O'Lakes in Kenya.
- Trial name
- NCT01226433
- Where
- Kenya
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- FHI 360
Oral Cancer, Palliative Supportive Care
Early Palliative Care For Patients With Oral Cancer in Sri Lanka
The goal of this quasi experimental study is to develop and assess the effectiveness of an early palliative care intervention in patients with oral cancer in Sri Lanka.
- Conditions
- Oral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of Patients
- Trial name
- NCT06726317
- Testing
- Early palliative care integration
- Where
- 4 sites in Sri Lanka
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Periodontal Diseases, Hypersensitivity Dentin
Clinical Efficacy of Vector Paro With Hydroxyapatite in the Supportive Therapy of Periodontitis
Enamel is the most calcified tissue in the body and is composed of 92-96% by organic substances in particular hydroxyapatite. Hydroxyapatite nanoparticles are similar to the morphology and structure of tooth enamel apatite…
- Conditions
- Periodontal Diseases, Hypersensitivity Dentin, Hydroxyapatite
- Trial name
- PAROXY (NCT07482280)
- Testing
- hydroxyapatite debridment, ultrasonic debridment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
HIV - Human Immunodeficiency Virus, Psychological Distress
Comparison of Acceptance and Commitment Therapy and Cognitive Behavior Therapy: Managing Psychological Distress and Its Multifaceted Impact on Stigmatization, Psychological Wellbeing, Social Support and Treatment Adherence in HIV/AIDS Patients
This is a randomized controlled trial comparing Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT) for HIV/AIDS patients at Sheikh Zayed Hospital.
- Trial name
- HIV CBT ACT (NCT07652918)
- Testing
- CBT, ACT+ Standard Care
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sadia Batool
Addictive Behavior, Alcohol Use Disorder
90-Day Online Substance Use Program
Individuals indicating risky substance use are randomly assigned either to a three-month online intervention on the Workit Health platform or a waitlist/treatment as usual.
- Conditions
- Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse
- Trial name
- NCT03069118
- Testing
- Treatment - Workit Health Online Program, Control - Resource List
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Workit Health
Stress Disorders, Post-traumatic, Substance Use Disorders
Peer Supported Web-based CBT for OEF/OIF Veterans With PTSD and Substance Misuse
Veterans who served in Iraq and Afghanistan have high rates of co-morbid PTSD symptoms and hazardous substance use (HSU). Evidence-based treatments for these problems are available in VA specialty clinics, but multiple barriers…
- Trial name
- NCT02611843
- Testing
- Peer-Supported Web CBT, Self-Managed Web CBT
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
Treatment Adherence and Compliance, Resistance Exercise
Testing a Smartphone App to Support a Mediterranean Diet and Strength Exercise
Eating a Mediterranean-style diet and doing regular resistance training are both known to lower the risk of heart disease. However, most people find it hard to stick to these habits over time, and few smartphone apps support both…
- Conditions
- Treatment Adherence and Compliance, Resistance Exercise, Mediterranean Diet, Healthy Volunteers
- Trial name
- App-etite (NCT07885254)
- Testing
- MedEx Tracker, Printed dietary and resistance exercise programme
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Breastfeeding, Sleep
Development of the Couplet Care Bassinet
The goal of this study is to evaluate the impact of the Couplet Care bassinet on maternal-infant outcomes in the postnatal hospital setting.
- Conditions
- Breastfeeding, Sleep, Patient Satisfaction
- Trial name
- NCT06533449
- Testing
- Couplet Care Bassinet, Standard Bassinet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hematopoietic Cell Transplantation, Oncology
Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation
Hematopoietic cell transplantation (HCT) is the only curative treatment modality for many hematologic malignancies. Morbidity and mortality rates have declined drastically over the years, secondary to improvements in both…
- Trial name
- IMPPACT (NCT04727827)
- Testing
- Pharmacogenomic-guided supportive care
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Physiological Conditions, Distress, Emotional
Hand in Hand: Feasibility of a Compassion-Focused App to Support Parents of Children With Mental Health Problems
Parents of children and adolescents with mental health problems may experience substantial caregiving burden and emotional distress, including persistent stress, self-criticism, shame, and parental burnout.
- Conditions
- Physiological Conditions, Distress, Emotional, Caregiving Stress, Burnout
- Trial name
- NCT07840404
- Testing
- App-based Compassion Program
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus