Clinical trials: Supportive Therapy
Urinary Tract Infections
Implementation Study With Decision Support Based on Data
This study evaluates the implementation of a machine learning based clinical decision support system for treatment of patients presenting with an urinary tract infection in general practice.
- Trial name
- NCT04408976
- Where
- Netherlands
- Volunteers
- 16,824 people
- Sponsor
- Leiden University Medical Center
Leukemia, Lymphoma
Rasburicase in Patients at High Risk for Tumor Lysis Syndrome (TLS) During Cycle-2
The goal of this clinical research study is to learn if using Elitek (rasburicase) for 2 cycles can help to control or prevent TLS better than 1 cycle of rasburicase and 1 cycle of allopurinol.
- Trial name
- NCT01200485
- Testing
- Rasburicase, Allopurinol
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- M.D. Anderson Cancer Center
Hematologic Malignancy, Old Age; Debility
Nutritional and Physical Exercise Intervention in Older Patients With Malignant Hemopathies
Clinical trial to analyze the impact of nutrition and physical exercise intervention program on the completion of treatment in older patients 70 years or older with malignant hemopathology
- Trial name
- ICOSENIORHEM (NCT04057443)
- Testing
- Nutritional support, Physical exercise, Hematologic Drug
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Maite Antonio, MD, Phd
Smoking Cessation, Second Hand Tobacco Smoke
The "Quit-for-Kids" Project: to Increase Abstinence and Protect Children From Tobacco Smoke Exposure
This project aims to test the effectiveness of an integrated intervention of brief cessation advice (AWARD), Nicotine Replacement Therapy, and Instant Messaging support compared with waitlist control participants among adult…
- Trial name
- NCT06127589
- Testing
- Brief cessation advice (AWARD), Nicotine Replacement Therapy (NRT), Instant messaging Support (IM)
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Esophagus Injury, Rectal Lesion
Suprasorb® CNPendo Used for Negative Pressure Therapy in the Oesophagus and Rectum to Support Defect and Wound Healing
A Post-Market Clinical Follow-up (PMCF) study designed as non-interventional, observational, prospective, multicentre study in a routine clinical care setting using a marketed medical device in line with the corresponding…
- Trial name
- Velox (NCT05476263)
- Where
- 7 sites in Germany
- Volunteers
- 110 people
- Sponsor
- Lohmann & Rauscher
Healthy Adult
The Effectiveness of Couple Therapy and Relationship Support
This randomized and controlled study investigates the effectiveness of relationship counselling and couple therapy in improving couples' relationship satisfaction and overall well-being.
- Trial name
- ECoT (NCT07604740)
- Testing
- Self-Help Program for Couples, Peloton Parisuhde (eng Fearless Relationship) Online Course, Manualized Short-Term EFT-Based Couple Intervention
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Diabetes Mellitus
Telemedicine for Reach, Education, Access and Treatment-ongoing
Diabetes (DM) management requires health care providers to provide patients with the appropriate amount of time, education and support that are necessary for quality care.
- Trial name
- TREAT-ON (NCT04107935)
- Testing
- TREAT-ON, Usual Care
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
LVAD (Left Ventricular Assist Device) Thrombosis, LVAD
STudy of Aspirin Removal in Patients Supported by the Fully Magnetically Levitated CH-VAD Pump
This multi-center, prospective, randomized, double-blinded, placebo-controlled study aims to investigate whether withdrawal of aspirin from the antithrombotic regimen in patients supported with the CH-VAD pump is non-inferior to…
- Conditions
- LVAD (Left Ventricular Assist Device) Thrombosis, LVAD, LVAD (Left Ventricular Assist Device), LVAD-related GI Bleed
- Trial name
- STAR (NCT07644247)
- Testing
- Warfarin (INR 2-3) with aspirin
- Volunteers
- 370 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronavirus Disease 2019 Infectious Disease (COVID-19 Infection)
Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19
This project investigates individual treatments using convalescent severe acute respiratory Syndrome Coronavirus 2 (SARS-CoV-2) plasma in SARS-CoV-2 infected patients at risk for disease progression.
- Trial name
- NCT04389944
- Testing
- convalescent plasma application to SARS-CoV-2 infected patients
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Substance Use Disorder (SUD)
Engaging Family Members During Early SUD Treatment: A Hybrid Trial
The goal of this study is a fractional factorial optimization trial to optimize engagement in a CRAFT program for family members with loved ones in outpatient treatment for a substance use disorder.
- Trial name
- NCT07579299
- Testing
- Engagement Strategy 1, Engagement Strategy 2, Engagement Strategy 3
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Performance Enhancement, Supportive Care
Effects of Wrestling Training on Psychological Well-Being, Anxiety, and Resilience in Adolescent Sedanter Boys
This randomized controlled study investigated the psychological effects of a six-week, non-competitive wrestling training program in sedentary adolescent boys.
- Trial name
- NCT07193121
- Testing
- Wrestling Group, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Coronary Artery Disease (CAD)
Micro-axial Flow Pump-Supported PCI in Complex Coronary Artery Disease With Ischemic LV Dysfunction
Based on a multi-center randomized controlled study, this research aims to evaluate the efficacy and safety of interventional therapy supported by the CorVad percutaneous left ventricular assist system (Micro-axial Flow Pump） for…
- Trial name
- PIVOT (NCT07678021)
- Testing
- Microaxial pump-supported PCI, Optimal medical therapy (OMT)
- Where
- China
- Volunteers
- 452 people
- Sponsor
- China National Center for Cardiovascular Diseases
Tuberculosis
Clinical Decision-support Reminders to Improve IPT Initiation Among HIV Positive Adults in Western Kenya
The overall research objective is to evaluate the impact of implementing a reminder system for medical providers to improve TB case-finding and isoniazid preventative therapy (IPT) for adults living with HIV in western Kenya
- Trial name
- TBTech (NCT01934309)
- Testing
- TB reminders
- Where
- Kenya
- Volunteers
- 3,782 people
- Sponsor
- Indiana University
Metastatic Colorectal Carcinoma
A Study to Estimate Overall Survival in Patients Receiving Best Supportive Care for Treatment-Resistant, Metastatic Colorectal Carcinoma
The primary objective of this study is to estimate overall survival in patients only receiving best supportive care (BSC) for treatment-resistant, metastatic colorectal carcinoma.
- Trial name
- NCT03096899
- Testing
- Observational
- Where
- United States
- Sponsor
- The Rogosin Institute
Supportive Care
SupporTive Care At Home Research for Patients with Progressive Neurologic Disease Patients (STAHR-Neuro) (HOMECARE)
To test the effects of home-based care on healthcare utilization within one Year (Hospitalization Status, Number of Hospitalizations, Unplanned Hospitalization Status, Number of Unplanned Hospitalizations, Length of Hospital…
- Trial name
- NCT06663514
- Testing
- SupporTive Care At Home
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- BeLong Cho
Shock, Critical Illness
Enteral Versus Parenteral Nutrition During Recovery After Shock
This study compares enteral nutrition and parenteral nutrition in critically ill adult patients recovering from shock while receiving decreasing doses of vasopressors in the intensive care unit.
- Conditions
- Shock, Critical Illness, Nutritional Support, Vasopressor Therapy
- Trial name
- NCT07411014
- Testing
- enteral nutrition, Parenteral Nutrition
- Where
- South Korea
- Volunteers
- 1,150 people
- Sponsor
- Samsung Medical Center
Self-Care, Self Efficacy
The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis
Web-based training based on the Self-Care Deficiency Theory has an effect on increasing self-care in in patients undergoing peritoneal dialysis.
- Conditions
- Self-Care, Self Efficacy, Perceived Social Support, Peritoneal Dialysis
- Trial name
- NCT04199338
- Testing
- The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Acute Myeloid Leukemia
A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Best Supportive Care as Maintenance Therapy in Japanese Participants With Acute Myeloid Leukemia (AML) in Complete Remission
The purpose of this study is to assess the efficacy and safety of oral azacitidine plus best supportive care versus best supportive care as maintenance therapy in a cohort of Japanese participants ≥ 55 years of age with Acute…
- Trial name
- NCT05197426
- Testing
- Oral Azacitidine
- Where
- 31 sites in United States, Japan
- Volunteers
- 19 people
- Sponsor
- Bristol-Myers Squibb
Glioblastoma, Glioblastoma Multiforme
The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)
There is no consensus on the optimal treatment of patients with high-grade glioma, especially when patients have limited functioning performance at presentation (KPS ≤70).
- Conditions
- Glioblastoma, Glioblastoma Multiforme, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, Adult
- Trial name
- PALSUR (NCT06146738)
- Testing
- Palliative Care, Tumor biopsy, Tumor resection
- Where
- 8 sites in United States, Belgium and 3 more
- Volunteers
- 1,015 people
- Sponsor
- Jasper Gerritsen
Atrial Fibrillation, Atrial Flutter
Impact of an Atrial Fibrillation Decision Support Tool (AFDST) on Thromboprophylaxis for Atrial Fibrillation
Study objective was to improve decision-making and thromboprophylaxis for patients with Atrial Fibrillation (AF) by developing and implementing a computerized decision support tool for individual patient-level decision-making…
- Trial name
- NCT02524977
- Testing
- Decision Support, Educational Intervention Only
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
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