Clinical trials: Supportive Therapy
Depression
Artificial Intelligence in Depression - Medication Enhancement
This study will determine the safety and potential effectiveness of a digital health platform aimed at improving treatment outcomes for patients with depression by assisting physicians with clinical decision making about…
- Trial name
- AID-ME (NCT04655924)
- Testing
- Clinical Decision Support System
- Where
- 11 sites in United States, Canada
- Volunteers
- 94 people
- Sponsor
- Aifred Health
Psychological Distress, Depression
Ensuring Quality in Psychological Support
The goal of this project is to test tools that will be part of a platform for training and supervision of mental health and psychosocial support helpers, including providers without specialized training in mental health.
- Trial name
- EQUIP (NCT04704362)
- Testing
- Ensuring Quality in Psychological Support, Standard Training and Supervision
- Where
- 7 sites in Ethiopia, Jordan and 5 more
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- George Washington University
Crohn Disease and Ulcerative Colitis
Bacillus Probiotic Spores in Supporting the Treatment of Chronic Inflammatory Bowel Disease
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a chronic relapsing intestinal disorder driven by immune dysregulation, impaired mucosal barrier function, and gut microbiome dysbiosis.
- Trial name
- NCT07799428
- Testing
- RO, LiveSpo® DIA30, LiveSpo® COLON
- Where
- Vietnam
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Breast Cancer, Stage III Breast Cancer
TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
This research is being done to assess whether an exercise intervention with protein intake support vs a health education and support program will make it easier for women age 65 or older who are receiving chemotherapy for breast…
- Conditions
- Breast Cancer, Stage III Breast Cancer, Breast Cancer Female, Stage I Breast Cancer
- Trial name
- THRIVE-65 (NCT05535192)
- Testing
- THRIVE, Health Education Support Program
- Where
- 4 sites in United States
- Volunteers
- 270 people
- Sponsor
- Dana-Farber Cancer Institute
Lung Cancer
Observational Study of Best Supportive Care With or Without Surgery, Chemo or Radiotherapy in Pts With Carcinoma of Lung
The purpose of this study is to establish a listing (database) of patients diagnosed with lung cancer and treated with best supportive care and standard and investigational chemotherapy regimens, surgery, and radiation therapy at…
- Trial name
- NCT00822016
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- New Mexico Cancer Research Alliance
Mixed Urinary Incontinence, Urinary Incontinence
Bladder Training Supported by Alarm Reminders and Distraction Techniques for Mixed Urinary Incontinence
This randomized controlled trial evaluated the effectiveness of bladder training supported by smartphone alarm reminders and distraction techniques in women with persistent mixed urinary incontinence who continued to experience…
- Trial name
- ARDT-MUI (NCT07689409)
- Testing
- Bladder Training Supported by Alarm Reminders and Distraction Techniques, Routine Outpatient Care
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Izmir Katip Celebi University
Human Immunodeficiency Virus (HIV)
Antiretroviral Treatment Strategies in Relation to Adherence, Resistance and Virological Treatment Failure
This project aims to assess different antiretroviral treatment strategies, optimally controlled and conventional, in relation to drug resistance and virological treatment failure.
- Trial name
- DotArv (NCT01433601)
- Testing
- Enhanced Treatment Support (ETS)
- Where
- Vietnam
- Volunteers
- 640 people
- Sponsor
- Karolinska Institutet
Multiple Sclerosis
Comprehensive Rehabilitation Programme in People With Multiple Sclerosis: The RECONNECT-MS Study
The goal of this clinical trial is to learn if a comprehensive rehabilitation programme can improve physical function, reduce fatigue, and raise quality of life in adults aged 18-65 with multiple sclerosis (MS).
- Trial name
- RECONNECT-MS (NCT07666958)
- Testing
- Individual Physiotherapy, Group Movement Awareness, Group Psychotherapy
- Where
- Czechia
- Volunteers
- 45 people
- Sponsor
- Charles University, Czech Republic
PTSD
Peer Enhanced Prolonged Exposure
The investigators plan to develop and test an intervention using peer specialists (Veterans who have managed PTSD and completed PE) to provide support services for Veterans using prolonged exposure therapy.
- Trial name
- PEET (NCT02818114)
- Testing
- Peer Enhanced Prolonged Exposure
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- VA Office of Research and Development
Childhood Obesity
An Evaluation of a Web-based System for Optimization of Behavioral Childhood Obesity Treatment
This study evaluates the families' and health care professional's experience from using a web based support system including mobile applications for self-monitoring weight and physical activity.
- Trial name
- NCT03380598
- Testing
- CLOSS, Usual care
- Where
- 3 sites in Sweden
- Volunteers
- 28 people
- Sponsor
- Karolinska Institutet
Cancer of Pancreas, Cancer of Stomach
Early Support in Primary Care for People Starting Treatment for Cancer
This is a feasibility, randomised controlled trial (RCT) of a person-centred care planning intervention involving patients recently diagnosed with a poor prognosis cancer who are starting a palliative oncology treatment in a…
- Conditions
- Cancer of Pancreas, Cancer of Stomach, Cancer of Esophagus
- Trial name
- GI-ACP (NCT03719716)
- Testing
- Anticipatory care planning letter
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- NHS Lothian
Macular Edema
Treatment of CNV With Aflibercept Combined With Pranoprofen Eye Drops or Nutraceutical Support With Omega-3
To determine whether a combination of intravitreal aflibercept and pranoprofen eyedrops or nutraceutical support provides additional benefit over IVA monotherapy for the treatment of choroidal neovascularization in age-related…
- Trial name
- NCT03355638
- Testing
- Aflibercept Injection [Eylea], Pranoprofen Eyedrops, Omega-3 Supplementation
- Volunteers
- 60 people
- Sponsor
- Università degli Studi di Brescia
Respiratory Syncytial Virus Infections
Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix…
- Trial name
- NCT05026749
- Testing
- AZM Group, Control Group
- Where
- 15 sites in United States
- Volunteers
- 370 people
- Sponsor
- University of Alabama at Birmingham
Cardiovascular Disease, Coronary Artery Disease
Exploring the Efficacy and Safety of Rivaroxaban to Support Elective Percutaneous Coronary Intervention
Balloon angioplasty (Percutaneous Coronary Intervention (PCI)) is commonly used to treat patients with obstructive coronary artery disease (CAD).
- Trial name
- X-PLORER (NCT01442792)
- Testing
- UFH, Rivaroxaban (Xarelto, BAY59-7939), Rivaroxaban (Xarelto, BAY59-7939) and UFH
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 108 people
- Sponsor
- Bayer
Lung Cancer
G-CSF and Pegfilgrastim in Treating Neutropenia in Patients Undergoing Radiation Therapy and Chemotherapy for Limited Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00554463
- Testing
- Filgrastim, Pegfilgrastim, Etoposide
- Where
- 14 sites in United States
- Volunteers
- 5 people
- Sponsor
- Radiation Therapy Oncology Group
Gastrointestinal Fistula, Enteral Nutritional Support
Enteral Versus Parenteral Nutrition in the Conservative Treatment of Upper Gastrointestinal Fistula After Surgery
The incidence of clinically significant anastomotic leaks (AL) after upper gastrointestinal (GI) surgery is approximately 4 % - 20 %, and the associated mortality can be as high as 80 % .
- Trial name
- NUTRILEAK (NCT03742752)
- Testing
- Enteral nutrition, Parenteral nutrition
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Lille
Healthy
Can Prebiotics Support the Treatment of Mild Iron Deficiency by Iron Supplementation
The first aim of this study is to investigate if daily administration of the prebiotic Synergy-1 (a commercial product consisting of oligofructose-enriched inulin) together with a common iron supplement (ferrous sulphate) during…
- Trial name
- NCT03850652
- Testing
- Prebiotic (Synergy-1) + Iron supplement
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gemma Walton
Multiple Myeloma
GEM05 for Patients With Multiple Myeloma Under 65 Years
The primary objective is to compare safety and efficacy of three induction treatments: VBMCP-VBAD / Velcade versus Thalidomide / Dexamethasone versus Velcade / Thalidomide / Dexamethasone.
- Trial name
- GEM05MENOS65 (NCT00461747)
- Testing
- VBMCP/VBAD/Velcade, Thalidomide/Dexamethasone, Velcade/Thalidomide/Dexamethasone
- Where
- 79 sites in Spain
- Volunteers
- 390 people
- Sponsor
- PETHEMA Foundation
HIV, AIDS
Adherence Support Intervention for Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia
The specific aim of the study is to assess antiretroviral therapy adherence and evaluate the impact of a situated treatment adherence intervention program among persons living with HIV/AIDS on antiretroviral therapy in Estonia.
- Conditions
- HIV, AIDS, Medication Adherence
- Trial name
- NCT01789138
- Testing
- Situated Optimal Adherence Intervention
- Where
- 2 sites in Estonia
- Volunteers
- 519 people
- Sponsor
- University of Tartu
Temporomandibular Joint Dysfunction Syndrome
The Application of Radio Frequency Waves
The aim of the study was to evaluate the influence of radio waves on the functioning of masseter muscles in the course of painful functional disorders of the organ, and thus the usefulness of these procedures in the treatment…
- Trial name
- NCT03773640
- Testing
- Radio frequency currents, Sonophoresis
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
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