Clinical trials: Supportive Therapy
Spinal Cord Injuries
Acute Intermittent Hypoxia and Body Weight Supported Treadmill Training for Incomplete Spinal Cord Injury Patients
Spinal cord injury (SCI) interrupts descending synaptic pathways from brainstem premotor neurons to spinal motor neurons, thereby paralyzing muscles below the neurological level.
- Trial name
- NCT02441179
- Testing
- Acute Intermittent Hypoxia, Body weight-assisted treadmill training
- Where
- 2 sites in Chile
- Volunteers
- 35 people
- Sponsor
- Sociedad Pro Ayuda del Niño Lisiado
Hearing Impaired
Educational Program for Hearing Aid Users With Internet Support
The purpose of this study is to examine the short-term effects of complementing an educational program for hearing aid users with Internet support.
- Trial name
- NCT01837550
- Testing
- Intervention group, Control group
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- Sodra Alvsborgs Hospital
Oral Mucositis in Head and Neck Cancer
Propolis for Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer
This clinical trial evaluated whether a 15% propolis solution could delay or prevent severe oral mucositis in patients with head and neck cancer receiving radiotherapy or concurrent chemoradiotherapy.
- Trial name
- NCT07597525
- Testing
- 15% Propolis solution, Standard oral care
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara Oncology Research and Training Hospital
Constipation - Functional
Efficacy of Educational Intervention as Supporting Element in the Treatment of Functional Constipation in Children
The purpose of this study is to determine whether educational intervention (recommendation of adequate fluid intake) is effective as an element supporting the treatment of functional constipation in children.
- Trial name
- NCT05191810
- Testing
- Educational information
- Volunteers
- 110 people
- Sponsor
- Medical University of Warsaw
Perihilar Cholangiocarcinoma
Biliary Drainage Plus HAIC in Locally Advanced pCCA
Biliary drainage and stent placement remains to be the main palliative treatment choice for advanced perihiliar cholangiocarcinoma (pCCA), and the life expectancy is only 4-6 months.
- Trial name
- NCT05024513
- Testing
- oxaliplatin and 5-fluorouracil, Biliary Drainage, Best Supportive Care
- Where
- China
- Volunteers
- 127 people
- Sponsor
- Peking University
Aging, Mild Cognitive Impairment
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
The purpose of the bpMedManage study is to rigorously test the efficacy of a smartphone technology to help improve high blood pressure medication adherence among older adults with mild cognitive impairment (MCI) in a 16-week…
- Conditions
- Aging, Mild Cognitive Impairment, Hypertension
- Trial name
- NCT06307574
- Testing
- bpMedManage
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Arizona
Quality of Life
The Impact of Feedback Informed Treatment in Floating Support Service
Feedback Informed Treatment (FIT) is a systematic feedback method. FIT is based on two simple questionnaires and aims to assess and improve the effectiveness of therapeutic treatment.
- Trial name
- FIT (NCT05357625)
- Testing
- Feedback Informed Treatment
- Where
- Denmark
- Volunteers
- 1,162 people, healthy volunteers welcome
- Sponsor
- VIVE - The Danish Center for Social Science Research
Type2 Diabetes, Medication Adherence
Improving Diabetes Medication Adherence for African Americans in Madison and Milwaukee Through Peer Support
The burden of diabetes is higher among African Americans (AAs) in Wisconsin as hospitalization rates for diabetes complications such as stroke and amputations are four times higher than whites and has worsened by 334% since 2011.
- Conditions
- Type2 Diabetes, Medication Adherence, Medication Nonadherence, Peer Support
- Trial name
- NCT04028076
- Testing
- Peers Supporting Health-Literacy, Self Efficacy, Advocacy and Adherence
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Anemia, Sickle Cell
Systematic Psychological and Medical Care for Children With SCD
Sickle cell disease (SCD), a genetically transmitted blood disease, necessitates life-long care. In children, the disease may cause intense pain and other severe complications.
- Trial name
- Drépano (NCT02022891)
- Testing
- systematic psychological care
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Major Depression
Efficacy of 18-Months of Antidepressive Medication Plus CBT or Dynamic or Supportive Psychotherapy for Recurrent Major Depression
Major Depressive Disorder affects approximately 16% of the adult population over the lifetime. Controlled studies indicate that short-term antidepressive medications or psychotherapy produce full remission in only about 46% of…
- Trial name
- NCT00220623
- Testing
- antidepressant medications, flexible drug choice, CBT, Psychodynamic or Supportive Psychotherapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Prostate Cancer
PROSAIC-DS Study (PROState AI in Cancer - Decision Support)
Around 375,000 cancers are diagnosed in the UK annually, with this figure expected to reach 500,000 by 2035. As the number of different cancer treatment options and our scientific understanding continue to grow rapidly, it can be…
- Trial name
- PROSAIC-DS (NCT05355727)
- Testing
- Clinical decision support tool recommended outcome
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Symptoms and Signs, Artificial Intelligence
BaiXiaoAi AI Companion for Cancer Patient Follow-up
This is a prospective, single-center, exploratory study designed to evaluate the accuracy, user engagement, and user experience of the BaiXiaoAi Companion AI.
- Conditions
- Symptoms and Signs, Artificial Intelligence, Artificial Intelligence Mobile Application, Needs Assessment
- Trial name
- NCT07396142
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 300 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Patient Engagement, Femoral Angiography
Use of Back Support After Transfemoral Angiography
In the routine treatment procedure after coronary angiography (CAG), the patients remain in the supine position for a long time, which leads to decreased venous return and back pain.
- Trial name
- NCT06643182
- Testing
- Back Support
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Inonu University
Mesothelioma
A Study Comparing Pemetrexed Plus Best Supportive Care Versus Best Supportive Care Alone in the Treatment of Mesothelioma
Based on results from earlier clinical trials, Pemetrexed may have antitumor activity as a first-line agent in the treatment of mesothelioma.
- Trial name
- NCT00190762
- Testing
- Pemetrexed
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Eli Lilly and Company
Depressive Disorder
Efficacy Study of a Computer Decision Support System to Treat Depression
The purpose of this study was designed to test the feasibility and effectiveness of implementing a Computerized Decision Support System for depression (CDSS-D) during acute care in a primary care setting.
- Trial name
- CDSS-D (NCT00551083)
- Testing
- Computerized Decision Support System for Depression (CDSS-D), Usual Care (UC)
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Substance Use
An Evaluation of the Pink Cloud Application in Post- Treatment Substance Use Disorder Support
This randomized controlled trial (RCT) will evaluate the feasibility and efficacy of Pink Cloud, a mobile health application designed to support recovery from substance and alcohol use disorders (SUD/AUD).
- Trial name
- NCT07042451
- Testing
- Pink Cloud, Active Control
- Where
- United States
- Volunteers
- 1,410 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Substance Abuse, Decision Making, Shared
Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Overdose Prevention
Oregon's decision makers (e.g., community service providers, public health, justice, advocacy groups, payers) are calling for comprehensive, current, and trusted data to inform how they allocate resources to improve substance use…
- Conditions
- Substance Abuse, Decision Making, Shared, Implementation Science, Decision Making
- Trial name
- D2A Oregon (NCT06852170)
- Testing
- Co-Design Sessions (CDS), Data products
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Prostate Cancer Patients
AI Chatbot for Prostate Radiation Therapy Patient Education
This study will evaluate whether an artificial intelligence chatbot can help patients better understand radiation therapy for localized prostate cancer.
- Trial name
- NCT07719062
- Testing
- AI Educational Chatbot
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Non Metastatic Breast Cancer
Support and Rehabilitation Protocol for Non Metastatic Breast Cancer Patients in Complete Remission After Chemotherapy
Many breast cancer patients (BCP) will gain weight during chemotherapy and about 10% of them are able to find back to their initial weight after all treatments are finished.
- Trial name
- NCT01563588
- Testing
- dietaty education, physical training, physiotherapy and SPA cares
- Where
- 2 sites in France
- Volunteers
- 251 people
- Sponsor
- Centre Jean Perrin
Polycystic Ovary
The Supporting Understanding of PCOS Education and Research (SUPER) Study
This research will test whether a Dietary Approaches to Stop Hypertension (DASH) or a very low-carbohydrate diet better improves outcomes like blood glucose control and body weight for adults with polycystic ovary syndrome.
- Trial name
- SUPER (NCT05452642)
- Testing
- DASH diet, Very low-carbohydrate diet
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Michigan
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