Clinical trials: Supportive Therapy
Sarcoma
Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With Osteosarcoma
RATIONALE: Radioactive drugs, such as samarium Sm 153 lexidronam pentasodium, may carry radiation directly to tumor cells and not harm normal cells.
- Trial name
- NCT00245011
- Testing
- filgrastim, ifosfamide, peripheral blood stem cell transplantation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Substance Use Disorder (SUD)
Engaging Family Members During Early SUD Treatment: A Hybrid Trial
The goal of this study is a fractional factorial optimization trial to optimize engagement in a CRAFT program for family members with loved ones in outpatient treatment for a substance use disorder.
- Trial name
- NCT07579299
- Testing
- Engagement Strategy 1, Engagement Strategy 2, Engagement Strategy 3
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Myelodysplastic Syndromes
Alternative Dosing Regimens of Subcutaneous Azacitidine for Myelodysplastic Syndromes
The purpose of this study is to determine if azacitidine, combined with Best Supportive Care (BSC), is effective in treating myelodysplastic syndromes (MDS) when given according to a different doses and dosing schedules.
- Trial name
- NCT00102687
- Testing
- azacitidine
- Where
- 31 sites in United States
- Volunteers
- 151 people
- Sponsor
- Celgene
Hearing Loss, Adult-Onset, Tinnitus
AI-assisted Diagnosis, Triage and Assessment of Hearing Loss and Tinnitus
Hearing loss affects approximately 11 million people in the UK, while tinnitus impacts around 7 million. Both conditions can significantly reduce quality of life and are linked to poorer mental health and employment challenges.
- Trial name
- NCT07586098
- Testing
- Artificial Intelligence (AI) Assisted Clinical Decision Support Tool for managing Hearing Loss and Tinnitus
- Where
- United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- Royal Cornwall Hospitals Trust
Edentulous Jaw
Unilateral Attachment Versus Tooth Implant Supported Bridge
Purpose: Evaluation of patients' satisfaction, biting force measurement and radiographic evaluation of abutment teeth of tooth implant supported bridge, unilateral attachment and conventional partial denture in mandibular distal…
- Trial name
- NCT04301115
- Testing
- attachment, bridge, CONVENTIONAL
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Nurse-led Supportive Care
Effects of Nurse-led Supportive Care Programme on Caregiver Burden and Resilience of Family Caregivers
Lung cancer is the leading cause of cancer-related deaths worldwide, with a mortality rate of 18%. The prognosis of lung cancer is progressive and devastating, which may cause patients to experience problems during the treatment…
- Trial name
- NCT06204289
- Testing
- Nurse-led Supportive Care Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Wilson Disease, Liver Failure
Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson's Disease-related Liver Failure
This study is to investigate the clinical efficacy of artificial liver support system using combination of plasma exchange and continuous hemodiafiltration in treatment of Wilson's Disease - related liver failure.
- Trial name
- NCT03589820
- Testing
- artificial liver support system
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Schizophrenia Spectrum Disorders (SSD)
Developing Biomarker-Supported Schizophrenia Spectrum Disorder (SSD) Prevention
The purpose of this study is to compare the effect of a brief family-based psychosocial intervention that addresses modifiable SSD risk factors on persistent and distressing psychotic-like experiences in children and young adults…
- Trial name
- NCT07743645
- Testing
- Psychosocial intervention group
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pulmonary Disease, COPD
The Virtual Reality Therapy as a Pulmonary Rehabilitation Supporting Method
This study evaluates the effectiveness of virtual reality (VR) therapy in the treatment of depression and anxiety symptoms in patients undergoing the pulmonary rehabilitation.
- Conditions
- Pulmonary Disease, COPD, Anxiety State, Stress
- Trial name
- NCT04601545
- Testing
- Pulmonary rehabilitation, Virtual therapeutic support
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Major Depressive Disorder
Controlled Study to Evaluate the Safety and Efficacy of the Predictix Antidepressant Clinician Support Tool
The study will compare two groups of patients: a control group of patients treated per the Standard of Care when prescribed with a medication for their Major depression disorder, versus a group of patients that used the Predictix…
- Trial name
- NCT04031157
- Testing
- Predictix Antidepressant
- Where
- 2 sites in Israel
- Volunteers
- 220 people
- Sponsor
- Taliaz Ltd.
Mothers, Infantile Colic
Supportive Care Training Given to Mothers of Babies With Infants Colic
Infantile Colic is a non-pathological condition that causes babies to cry excessively throughout their first few months of life.
- Trial name
- NCT06197100
- Testing
- Supportive care training, control grups
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Vulvar Cancer, Quality of Life
Quality of Life, Unmet Needs and Satisfaction With Care After Vulvar Cancer
The aim of this prospective, longitudinal Swedish multi-center study is to assess the quality of life, treatment-related morbidity, unmet needs and satisfaction with care after treatment for vulvar cancer, evaluated by a…
- Trial name
- PROVE (NCT04152512)
- Testing
- Questionnaire administration
- Where
- 4 sites in Sweden
- Volunteers
- 153 people
- Sponsor
- Karolinska University Hospital
Lung Cancer
CareSTEPS: A Supportive Care Program for the Caregivers of Advanced Lung Cancer Patients
The CareSTEPS intervention fills an important service gap by providing education, skills training, and support to the caregivers of advanced lung cancer patients on active treatment.
- Trial name
- NCT02414672
- Testing
- CareSTEPS
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Baylor College of Medicine
Chronic Kidney Disease
Shared Decision Making and Renal Supportive Care
This year, 90,000 Americans with end-stage renal disease (ESRD) will die and questions will legitimately be raised as to whether terminal treatment and location of death adequately represented their preferences.
- Trial name
- SDMRSC (NCT02405312)
- Testing
- advance care planning
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Baystate Medical Center
Diabetes Mellitus, Type 2, Housing Problems
Diabetes Homeless Medication Support
This randomized pilot trial of the Diabetes Homeless Medication Support intervention vs. brief diabetes education will test the perception and feasibility of anticipated study procedures and refine randomization and blinding.
- Conditions
- Diabetes Mellitus, Type 2, Housing Problems, Psychological Distress
- Trial name
- D-HOMES (NCT05258630)
- Testing
- Diabetes Homeless Medication Support (D-Homes), Enhanced usual care
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hennepin Healthcare Research Institute
Peri-Implantitis and Peri-implant Mucositis
SPiT-frequency I_Peri-implant Mucositis
This is an interventional clinical study on the peri-implant treatment necessary to improve the clinical conditions surrounding dental implants registered with peri-implant inflammation.
- Trial name
- NCT06737328
- Testing
- Submocosal instrumentation using a ultrasonic device (PEEK). Submucosal cleaning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Oslo
Kidney Diseases, Chronic Kidney Diseases
Pathways Project: Kidney Supportive Care
The Pathways Collaborative is the first attempt to implement supportive (palliative) kidney care at multiple sites in the United States.
- Conditions
- Kidney Diseases, Chronic Kidney Diseases, End Stage Renal Disease, End Stage Renal Disease on Dialysis
- Trial name
- NCT04125537
- Testing
- IHI Breakthrough Collaborative Model
- Where
- 13 sites in United States
- Volunteers
- 476 people
- Sponsor
- George Washington University
HIV Infections
Adherence Interventions for HIV Youth Via Text & Cell Phone - Sequential Multiple Assignment Randomized Trial (SMART)
The purpose of this study is to test an adaptive adherence intervention, which utilizes two mobile health (mHealth) intervention designs, in an effort to promote adherence to antiretroviral therapy (ART) and achieve and maintain…
- Trial name
- SMART (NCT03535337)
- Testing
- CPS, SMS
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Florida State University
Breast Cancer, Knowledge, Attitudes, Practice
Randomized and Multicenter Study to Evaluate a Customizable Support Breast Cancer Material
The goal of this clinical trial is to evaluate if a customizable support material allows to improve the knowledge about the stage and subtype of the disease, as well as the indicated treatments, in comparison with a…
- Conditions
- Breast Cancer, Knowledge, Attitudes, Practice, Patient Empowerment, Patient Satisfaction
- Trial name
- NCT05798312
- Testing
- Customizable support material, Non-customizable support material
- Where
- Mexico
- Volunteers
- 125 people
- Sponsor
- Medicos e Investigadores en la Lucha contra el Cancer de Mama
Psychotic Disorder
Mobile After-Care Support App: Pilot RCT
The overall aim of this program of research is to refine and test the feasibility and acceptability of a newly developed mobile device-delivered app, called Mobile After-Care Support (MACS), to improve patients' coping and…
- Trial name
- MACS-RCT (NCT03955250)
- Testing
- Mobile After-Care Support (MACS) app, Mobile app attention control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Butler Hospital
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