Clinical trials: Supportive Therapy
Chronic Pain, Back Pain
Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain
The goal of this clinical trial is to learn how well two community-based self-management programs work in people with chronic back or neck pain.
- Conditions
- Chronic Pain, Back Pain, Neck Pain, Self-management
- Trial name
- P4P (NCT06696352)
- Testing
- Partners4Pain, Keys to Wellbeing
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- University of Minnesota
Oral Mucositis
A Trial Assessing Chemo Mouthpiece Device With Best Supportive Care for Symptoms of Chemotherapy-Induced Oral Mucositis
This study will compare the use of the Chemo MouthpieceTM device along with best supportive oral care to best supportive oral care alone to rate the effectiveness of Chemo MouthpieceTM in lessening symptoms associated with…
- Trial name
- NCT04595838
- Testing
- Chemo Mouthpiece, Best Supportive Care only
- Where
- 11 sites in United States
- Volunteers
- 176 people
- Sponsor
- Chemo Mouthpiece
Hematologic Malignancy, Myelodysplastic Syndromes
Home Blood Transfusions
This is a pilot single arm study to evaluate the feasibility and acceptability of a home blood transfusion program. Patients will be enrolled with hematologic malignancies and other bone marrow failure syndromes who are…
- Conditions
- Hematologic Malignancy, Myelodysplastic Syndromes, Acute Myeloid Leukemia, Transfusion Dependent Cytopenias
- Trial name
- NCT07121140
- Testing
- Home Blood Transfusion
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Thomas Jefferson University
Squamous Cell Carcinoma of Hypopharynx, Squamous Cell Carcinoma of Larynx
Scheduled IV Fluids in the Supportive Management of Patients Undergoing Chemo-radiotherapy for Head and Neck Cancer
Patients undergoing concurrent chemoradiotherapy (CCRT) for head and neck squamous cell carcinoma frequently experience treatment-related toxicities including mucositis, dysphagia, acute kidney injury, pain, constipation…
- Conditions
- Squamous Cell Carcinoma of Hypopharynx, Squamous Cell Carcinoma of Larynx, Squamous Cell Carcinoma of Oropharynx, Squamous Cell Carcinoma of Oral Cavity
- Trial name
- NCT07784855
- Testing
- Scheduled IV Hydration, Clinician Assessment-Based IV Hydration
- Where
- 6 sites in United States
- Volunteers
- 180 people
- Sponsor
- West Virginia University
Chronic Kidney Disease
Expanding and Promoting Alternative Care and kNowledge in Decision-making Trial
The goal of this clinical trial is to compare two health system-based approaches for offering kidney failure treatment options to older patients with kidney failure, specifically, to ensure patients are actively involved in a…
- Trial name
- ExPAND (NCT06243068)
- Testing
- Educate and Engage, Educate and Engage Plus Kidney Supportive Care Program
- Where
- 25 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- George Washington University
Hematopoietic Cell Transplant, Hematologic Malignancy
Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation
Primary PC - or training HCT clinicians to deliver PC domains as part of routine practice - is an alternative model of supportive care. We have developed Sentinel, a primary PC intervention for HCT clinicians and patients.
- Trial name
- Primary PC HCT (NCT06676852)
- Testing
- Primary palliative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Non Small Cell Lung Cancer
The Effect of Nurse Navigation Program on Lung Cancer Patients
The study aims to determine the effect of the nurse navigation program (LungCaNN), which is performed in line with the supportive care needs of newly diagnosed non-small cell lung cancer patients, on the level of…
- Trial name
- [LungCaNN] (NCT05937425)
- Testing
- LungCaNN
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Akdeniz University
Pediatric Cancer
Cope 360 App for Caregivers of Children With Cancer
To date, most caregiver focused interventions have been targeted at caregivers of adults with cancer, completely ignoring the unique needs of caregivers of children with cancer.
- Trial name
- NCT05112458
- Testing
- Cope 360 mobile health application, Usual care
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Exercise Therapy, Juvenile Idiopathic Arthritis
Effects of Telemonitoring-supported Game-based Home Exercises in Juvenile Idiopathic Arthritis
In order to cope with pain, improve quality of life and prevent kinesiophobia in children with juvenile idiopathic arthritis, most of the physiotherapy approaches used so far are standard.
- Trial name
- NCT05837247
- Testing
- Game-based telerehabilitation exercises, Home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul University - Cerrahpasa
Devic's Disease
Hematopoietic Stem Cell Transplant in Devic's Disease
This study is designed to examine whether treating Devic's disease patients with high dose cyclophosphamide together with rabbit antithymocyte globulin (rATG)/rituximab (drugs which reduce the function of the immune system)…
- Trial name
- NCT00787722
- Testing
- Hematopoietic Stem Cell Transplantation, Cyclophosphamide, G-CSF
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Northwestern University
Child Obesity
Enhancing Family Based Treatment of Childhood Obesity Through Social Networks
The purpose of this study is to develop a Social Network Engagement (SNE) Intervention that will be integrated into a standard treatment program for childhood overweight.
- Trial name
- CONNECT (NCT02206529)
- Testing
- Social Network Engagement+Std Treatment, Standard Treatment
- Volunteers
- 25 people
- Sponsor
- Kaiser Permanente
HIV Seropositivity, Adherence, Medication
Supporting Health Behavior Among Persons Living With HIV Using Tech, MOST, and Behavioral Economics
The present study focuses on adult persons living with HIV in the New York City and Newark, New Jersey metropolitan areas who are not highly adherent to HIV medication and who do not evidence undetectable HIV viral load (the…
- Trial name
- SCAP2 (NCT04518241)
- Testing
- MI sessions, TMQQ, Type of compensation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- New York University
Hemodialysis, End Stage Renal Disease
The Effectiveness and the Safety of Acupuncture for Symptomatic Care of Hemodialysis Patients: A Case-series
Purpose: Hemodialysis-dependent patients with an end-stage renal disease (ESRD) suffer from a number of distressing symptoms, such as pain, poor mental health, fatigue, sleep disturbance and pruritus.
- Trial name
- NCT00883831
- Testing
- Individualized manual acupuncture
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Korea Institute of Oriental Medicine
Class II Division 1 Malocclusion
Comparison Between Mini Implant Supported Appliance and Headgear in Treatment of Maxillary Excess in Growing Patients
The aim of the study is to compare an Infra-zygomatic Mini implant supported appliance with headgear in distalization and intrusion of maxillary dentition for treatment of growing patients with class II malocclusion (maxillary…
- Trial name
- NCT03839303
- Testing
- Infra-zygomatic Mini Implant Supported Appliance, high pull head gear
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Stroke
SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke
SEACOAST 1 is a prospective, randomized, blinded endpoint trial comparing collateral vigor and clinical outcomes, with different forms of GA in patients with acute ischemic stroke due to anterior circulation large vessel…
- Trial name
- SEACOAST (NCT03737786)
- Testing
- Tight control of end-tidal CO2 levels
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Depression in Adults, Anxiety
Structured Group Therapy in Reducing Depression and Anxiety in Pakistan
This study aims to assess the effectiveness of Cognitive Behavioural Therapy (CBT) and Mindfulness-Based Stress Reduction (MBSR) in group settings to reduce symptoms of depression and anxiety, enhance emotional resilience, and…
- Trial name
- NCT07239388
- Testing
- Structured group therapy
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Soft Tissue Sarcoma
Trial Comparing Trabectedin to the Best Supportive Care in Patients With Sarcoma
As the transparency committee of the Haute Autorité de Santé pointed out due to lack of data regarding comparative trial of Yondelis versus best supportive care, activity of Yondelis in soft tissue sarcoma remain to be assessed.
- Trial name
- TSAR (NCT02672527)
- Testing
- Trabectedin, Dexamethasone
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Hematopoietic Cell Transplantation, Oncology
Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation
Hematopoietic cell transplantation (HCT) is the only curative treatment modality for many hematologic malignancies. Morbidity and mortality rates have declined drastically over the years, secondary to improvements in both…
- Trial name
- IMPPACT (NCT04727827)
- Testing
- Pharmacogenomic-guided supportive care
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cancer
Behavioral Coaching Intervention (Laguna Health) for Patients With Cancer
The overall goal of this study is to examine the feasibility, acceptability, and preliminary efficacy of using a behavioral coaching intervention (Laguna Health) for optimizing post-hospital discharge care in patients with…
- Trial name
- LAGUNA (NCT06004141)
- Testing
- Laguna Health
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Massachusetts General Hospital
Prolonged Grief Disorder (PGD)
Technology-supported Interventions for Prolonged Grief Disorder (PGD)
The main aim of this project is to test the efficacy of two formats of delivering an internet- based treatment(GROw) for Prolonged Grief Disorder (PGD) in order to enhance treatment adherence: in a blended format (that combines…
- Trial name
- NCT06932120
- Testing
- Internet-based treatment (GROw) combined with face-to-face videoconferencing sessions with a therapist in BF-GROw group, Internet-based treatment (GROw) supported by the App developed which contains the EMA and EMI tools in iGROw group.
- Where
- 2 sites in Spain
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
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