Clinical trials: Supportive Therapy
Myelodysplastic Syndrome
Decitabine Versus Supportive Care in Adults With Advanced-stage MDS
To compare the safety and efficacy profiles of decitabine to those of supportive care in adults with advanced-stage myelodysplastic syndrome (MDS)
- Trial name
- NCT00043381
- Testing
- decitabine (5-aza-2'deoxycytidine)
- Where
- 24 sites in United States
- Volunteers
- 160 people
- Sponsor
- Astex Pharmaceuticals, Inc.
Depressive Disorder, Treatment-Resistant
rTMS With and Without Text4Support for the Treatment of Resistant Depression.
This study is a multicenter prospective, parallel design, two-arm, rater-blinded randomized controlled pilot trial. Participants will be randomly assigned to one of two treatment conditions.
- Trial name
- NCT05570344
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Repetitive Transcranial Magnetic Stimulation (rTMS) Plus Text4Support
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Diarrhea, Enteritis
Prospective Randomized Open Label Study of the Treatment of Therapy-associated Diarrhea During Percutaneous Radiation Therapy of the Small Pelvis. - Comparison of Loperamide and Tincture of Opium -
Therapy-associated diarrhea during radiation therapy of small pelvis (including enteritis as a result of radiation therapy and enteritis as a result of radiation- and chemotherapy) is a common problem in multimodal cancer…
- Conditions
- Diarrhea, Enteritis, Cancer
- Trial name
- Loop (NCT00444093)
- Testing
- Opii normata treatment, Loperamid Treatment
- Volunteers
- 1 people
- Sponsor
- Philipps University Marburg
Cancer Patients, Young Adult
Bright IDEAS - Young Adults Problem-Solving Skills Training
The purpose of this project is to evaluate efficacy of Bright IDEAS, an evidence-based problem-solving skills training (PSST) program, as a supportive care intervention for young adult (YA) cancer patients compared with enhanced…
- Conditions
- Cancer Patients, Young Adult, Supportive Care
- Trial name
- NCT04585269
- Testing
- Bright IDEAS-YA
- Where
- 3 sites in United States
- Volunteers
- 344 people
- Sponsor
- Rutgers, The State University of New Jersey
Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers
Glove Compression for Chemotherapy-Induced Neuropathy
This study investigates whether wearing tight-fitting surgical gloves on the non-dominant hand could help prevent chemotherapy-induced peripheral neuropathy (CIPN) in women with gynecologic cancers treated with paclitaxel.
- Conditions
- Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers, Ovarian Cancer (OvCa), Endometrial Cancer
- Trial name
- NEURO-GLOVE (NCT07105553)
- Testing
- Surgical Glove Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Multiple Sclerosis, Neurorehabilitation
Comprehensive Therapeutic Program For People With Multiple Sclerosis
This study investigates the effectiveness of an intensive multidisciplinary rehabilitation program for people with multiple sclerosis (PwMS).
- Conditions
- Multiple Sclerosis, Neurorehabilitation, Rehabilitation, Rehabilitation Exercise
- Trial name
- BIB_MS (NCT07248657)
- Testing
- Outpatient physiotherapy, group psychotherapy
- Where
- Czechia
- Volunteers
- 26 people
- Sponsor
- Charles University, Czech Republic
Human Immunodeficiency Virus (HIV)
Antiretroviral Treatment Strategies in Relation to Adherence, Resistance and Virological Treatment Failure
This project aims to assess different antiretroviral treatment strategies, optimally controlled and conventional, in relation to drug resistance and virological treatment failure.
- Trial name
- DotArv (NCT01433601)
- Testing
- Enhanced Treatment Support (ETS)
- Where
- Vietnam
- Volunteers
- 640 people
- Sponsor
- Karolinska Institutet
Caregiver Burden, Depressive Symptoms
Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong
The goal of this cluster randomized controlled trial study is to compare the effectiveness of a novel psychosocial intervention based on Cognitive Behavioral Therapy, lifestyle intervention and effective communication skills in…
- Conditions
- Caregiver Burden, Depressive Symptoms, Quality of Life, Self Efficacy
- Trial name
- NCT06473012
- Testing
- Cognitive Behavioral Therapy for Caregivers of Older Adults, Control intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Nutrition
A Study on Nutrition Support Therapy of Patients With Liver Failure
This study is a Clinical trial to assess the efficacy of nutrition support therapy of patients with liver failure. Patients were randomized to one of 2 groups to receive different nutrition and energy support treatment.
- Trial name
- NCT03944330
- Testing
- standard hospital diet
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Localized Breast Cancer
"Mon Parcours de Vie" Localized Breast Cancer: Announcement, Support, Information on the Disease and Treatments. Pilot Study to Assess the Value of Written Information Documents.
Since late 2019, the French association "MON PARCOURS DE VIE" has developed books donated by caregivers at cancer centers in France. These documents are available online: https://www.monparcoursdevie.fr/.
- Trial name
- MaVie (NCT07165756)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Institut de Cancérologie de Lorraine
Cognitive Therapy
MEDi Robot for Pain Management at Induction
The purpose of this study is to determine if a preparation teaching intervention before IV insertion, taught by MEDi to children and their parents, will lead to lower levels of expected and experienced pain and fear and less…
- Trial name
- NCT02859051
- Testing
- Humanoid Robot MEDi
- Where
- Canada
- Volunteers
- 137 people
- Sponsor
- University of Calgary
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Prehabilitation
Multimodal Prehabilitation Program That Combines Physical Exercise, Psychological Intervention and Nutritional Support to Improve the Response to Neoadjuvant Chemoterhapy in Early Breast Cancer Patients
The aim of this clinical trial is to evaluate whether following a multimodal prehabilitation program including physical exercise, nutritional support and psychological intervention during neoadjuvant chemotherapy in breast cancer…
- Trial name
- DIANA (NCT07107594)
- Testing
- Multimodal prehabilitation
- Where
- Spain
- Volunteers
- 214 people
- Sponsor
- Hospital Clinic of Barcelona
Diabetes
Leveraging Interventions for Needs and Knowledge in Diabetes
Unmet social needs and economic burden persist as key reasons why one-third of people with diabetes have poor disease control. The purpose of this study is to learn whether different tools and types of support may help people…
- Trial name
- LINKD (NCT07676188)
- Testing
- FindHelp, Peer Support, Social Work
- Where
- United States
- Volunteers
- 694 people
- Sponsor
- University of Michigan
Tuberculosis
Self-verification and Support Via Mobile Phones Drastically Improves Tuberculosis Treatment Success in LMIC Settings
Each year, 10.4 million patients are diagnosed with and 1.8 million people die from Tuberculosis (TB). Despite the availability of highly effective and accessible medications in the developing world where TB is endemic, the 6-18…
- Trial name
- NCT03135366
- Testing
- Keheala, Standard of Care
- Volunteers
- 1,190 people
- Sponsor
- Yale University
Diarrhea Infectious, Algorithms
The Utility and Feasibility of Accessible Diarrhea Etiology Prediction Tool (ADEPT) in an Informal Healthcare Setting
Diarrheal disease remains a leading cause of morbidity and mortality for children under 5 globally. Accepted best practice for managing diarrhea in the absence of blood or suspicion of cholera is rehydration, however in resource…
- Conditions
- Diarrhea Infectious, Algorithms, Decision Support Systems, Clinical, Clinical Decision-making
- Trial name
- NCT07538531
- Testing
- Diagnostic test: Accessible Diarrhea Etiology Prediction Tool (ADEPT)
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- Daniel Leung
Emergency
Telemedical Support for Prehospital Emergency Medical Service
The purpose of this study is to evaluate the safety and quality of a pre-hospital holistic multifunctional teleconsultation system.
- Trial name
- TEMS (NCT02617875)
- Testing
- conventional EMS physician, tele-EMS physician
- Where
- Germany
- Volunteers
- 3,534 people
- Sponsor
- RWTH Aachen University
Acute Myeloid Leukemia (AML)
A Study of Oral Venetoclax Tablets and Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy
This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in combination with azacitidine (AZA).
- Trial name
- VIALE-M (NCT04102020)
- Testing
- Venetoclax, Azacitidine
- Where
- 156 sites in United States, Australia and 17 more
- Volunteers
- 112 people
- Sponsor
- AbbVie
Malignant Neoplasms, Tuberculosis (TB)
Prophylaxis of Complications of Basic Therapy Using Naderin in Socially Significant Diseases
This interventional study evaluated the efficacy of Naderin (sodium nucleinate) for the prophylaxis of complications during basic therapy and medical rehabilitation in patients with socially significant diseases, including…
- Conditions
- Malignant Neoplasms, Tuberculosis (TB), HEPATITIS C (HCV)
- Trial name
- NADERIN-SSD (NCT07671508)
- Testing
- Naderin, Standard Therapy
- Volunteers
- 75 people
- Sponsor
- MIPO Clinic
Social Climate, Compassion
Improving Social Climate in Secure Settings With a Compassion Focused Staff Intervention
This study evaluates the effectiveness of a Compassion Focused Staff Support (CFSS) intervention in improving the social climate of correctional and forensic psychiatric institutions.
- Conditions
- Social Climate, Compassion, Critical Incident, Staff Support
- Trial name
- NCT07135518
- Testing
- Compassion Focused Staff Support, CFT Workshop
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Psychiatric Clinics Basel
Chronic Stroke
Comparison of NT Vs Body Weight Supported TT Along With CT on Lower Extremity in Chronic Stroke Patients
To determine the effect of Neurodevelopment Treatment vs Body Weight Supported Treadmill Training along with conventional therapy on lower extremity among chronic stroke patients.
- Trial name
- NCT05376982
- Testing
- Neurodevelopmental Treatment, Body weight supported treadmill training along with conventional therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Superior University
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