Clinical trials: Supportive Therapy
Acute Hypoxemic Respiratory Failure
ROX Index for the Timing of Intubation in Nasal High Flow
Late or delayed intubation in patients with acute hypoxemic respiratory failure (AHRF) treated with nasal high flow (NHF) is associated with increased patient mortality.
- Trial name
- ROX-1 (NCT04707729)
- Testing
- ROX index algorithm
- Where
- 12 sites in United States, China and 1 more
- Volunteers
- 630 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Brain Metastases
Supportive Care With or Without Repeated Whole Brain Radiotherapy in Patients With Recurrent Brain Metastases
Patients with solid cancers may develop cerebral metastases, requiring whole brain radiotherapy (WBRT). Furthermore, in several cases, a secondary course of WBRT might be required due to intracerebral recurrence and limited…
- Trial name
- RECARE (NCT04084431)
- Testing
- Radiation, OSC
- Where
- Germany
- Sponsor
- University Hospital Heidelberg
Edentulous Mouth, Edentulous Jaw
Mandibular Overdentures Retained by Conventional or Mini Implants
This study aims to compare mandibular overdentures retained either by mini or standard size implants as a treatment for edentulous adults, in terms of patient-reported satisfaction and oral health-related quality of life.
- Trial name
- NCT01411683
- Testing
- Implant-retained mandibular overdenture
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Non-Metastatic Breast Carcinoma, Remission
Support and Post-therapeutic Rehabilitation for Women in Complete Remission of Breast Cancer in a Thermal Environment
The PACThe - Real life project is a post-therapeutic support and rehabilitation for women in complete remission of breast cancer in a thermal environment.
- Conditions
- Non-Metastatic Breast Carcinoma, Remission, Quality of Life
- Trial name
- PACTHE-VR (NCT05433077)
- Where
- 15 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Jean Perrin
Diabetes Mellitus, Type 2, Housing Problems
Diabetes Homeless Medication Support
This randomized pilot trial of the Diabetes Homeless Medication Support intervention vs. brief diabetes education will test the perception and feasibility of anticipated study procedures and refine randomization and blinding.
- Conditions
- Diabetes Mellitus, Type 2, Housing Problems, Psychological Distress
- Trial name
- D-HOMES (NCT05258630)
- Testing
- Diabetes Homeless Medication Support (D-Homes), Enhanced usual care
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hennepin Healthcare Research Institute
Malignant Brain Tumor, Glioma
Supportive Psychoeducational Intervention for Patients With Brain Tumors (Acceptance and Commitment Therapy-based Supportive Intervention for Patients With Central Nervous System Tumors)
The goal of this study is to refine and test a psychosocial intervention called ASCENT (ACT-based Supportive intervention for patients with CENTral nervous system tumors).
- Conditions
- Malignant Brain Tumor, Glioma, Coping Skills, Distress, Emotional
- Trial name
- ASCENT (NCT06099743)
- Testing
- Psychosocial intervention, Usual supportive care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Cardiogenic Shock, Extracorporeal Membrane Oxygenation
Efficacy and Safety of Synchronized Cardiac Support in Cardiogenic Shock Patients
The study aims to investigate the safety and efficacy of the Synchronized Cardiac Support treatment wit the icor kit and the Xenios console with modified sensor box ECG and Software Version 3.2.4
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation, ECLS, VA ECMO
- Trial name
- PulseSE (NCT05106491)
- Testing
- Synchronized Cardiac Support with the icor kit
- Where
- 2 sites in Germany
- Volunteers
- 21 people
- Sponsor
- Xenios AG
Multiple Sclerosis
Comprehensive Rehabilitation Programme in People With Multiple Sclerosis: The RECONNECT-MS Study
The goal of this clinical trial is to learn if a comprehensive rehabilitation programme can improve physical function, reduce fatigue, and raise quality of life in adults aged 18-65 with multiple sclerosis (MS).
- Trial name
- RECONNECT-MS (NCT07666958)
- Testing
- Individual Physiotherapy, Group Movement Awareness, Group Psychotherapy
- Where
- Czechia
- Volunteers
- 45 people
- Sponsor
- Charles University, Czech Republic
Hepatitis C, Liver Cirrhosis
Effects of Low-dose Maintenance Peg Interferon Alfa-2b Therapy Versus Supportive Care in Patients With Cirrhotic Hepatitis C With HIV (Study P04371)
This is a Phase 3b, randomized, open-label, parallel-group, multi-center, multi-national study of low-dose maintenance Peg interferon alpha-2b (Peg-Intron®) in subjects with human immunodeficiency virus-hepatitis C virus…
- Conditions
- Hepatitis C, Liver Cirrhosis, HIV Infections
- Trial name
- NCT00381017
- Testing
- Peg interferon alpha-2b
- Sponsor
- Merck Sharp & Dohme LLC
Dementia
Virtual Reality Training to Support Daily Activities for People Living With Dementia
This study will test whether a home-based virtual reality training program can help people living with dementia practice everyday activities.
- Trial name
- NCT07829913
- Testing
- At-Home VR-Based IADL Training, Cognitive Stimulation Activities
- Volunteers
- 40 people
- Sponsor
- Indiana University
Joint Prosthesis, Breast Implants
A Randomized Study of Superiority of POSToperative Pharmaceutical Support on Patients' Knowledge of Their IMPlant
Recently joint and breast prostheses were placed under special post-marketing surveillance in order to prevent new occurrence of serious incidents by agency for medicines and health products safety.
- Conditions
- Joint Prosthesis, Breast Implants, Health Education
- Trial name
- POSTIMP (NCT04302233)
- Testing
- New pharmaceutical support (NPS)
- Where
- France
- Volunteers
- 236 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
Design and Evaluation of the Effects of a Physical Therapy Program With Digital Support in Patients With Breast Cancer
Breast cancer surgery usually results in reduced range of motion of the shoulder joint, weakness of the musculature and altered scapular kinematics during movement.
- Trial name
- NCT04837248
- Testing
- Active Comparator: Group 1. Conventional treatment, Experimental: Group 2. Experimental treatment.
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Psychosocial Problem, Psychological Distress
Evaluating Impacts of CSS for Veterans and Their Families in Ukraine
This cluster-randomized controlled trial (c-RCT) evaluates the effectiveness of a brief, single-session psychosocial workshop, "CETA Short Session" (CSS), for reducing symptoms of distress and functional impairment and increasing…
- Conditions
- Psychosocial Problem, Psychological Distress, Engagement, Patient
- Trial name
- NCT04234815
- Testing
- CETA Short Session (CSS), Psychoeducation and Safety
- Where
- Ukraine
- Volunteers
- 1,193 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cancer, Psychological Distress
Support and Healing Intervention for Adolescents With a Parent Diagnosed With Cancer (SHINE)
e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed…
- Conditions
- Cancer, Psychological Distress, Adaptation, Psychological
- Trial name
- SHINE (NCT07751185)
- Testing
- SHINE Psychosocial Intervention, Usual Supportive Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Rheumatoid Arthritis
Supporting Patient Care With Electronic Resources in the United States
This proof-of-concept randomized trial evaluates the effectiveness of using an online decision aid (US-ANSWER-2) in the decision-making to start or switch biologic therapy in US patients with rheumatoid arthritis.
- Trial name
- SuPER-US (NCT02787538)
- Testing
- US-ANSWER-2 decision aid, Control group (Online medication guide)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Non Small Cell Lung Cancer
The Effect of Nurse Navigation Program on Lung Cancer Patients
The study aims to determine the effect of the nurse navigation program (LungCaNN), which is performed in line with the supportive care needs of newly diagnosed non-small cell lung cancer patients, on the level of…
- Trial name
- [LungCaNN] (NCT05937425)
- Testing
- LungCaNN
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Akdeniz University
Type 1 Diabetes
Effectiveness of a Multidisciplinary Treatment and Structured Education Programme
This trial compared an structured education programme and multidisciplinary treatment vs an standard treatment in type 1 diabetes patient, the Primary outcome is glycemic control at 6-month follow up and secondary outcome are…
- Trial name
- NCT06184815
- Testing
- Educational programme 12, Standard education and treatment
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Respiration Disorders
To Identify if a COPD Self-management App Can Safety and Appropriately Identify When Patients Are Not on the Best Medication Plan for Their COPD Symptoms and Support Their COPD Management.
Although COPD cannot be cured, managing COPD can help reduce symptoms control, slows progression of the disease, and may improve the quality of life.
- Trial name
- mySmartCOPD (NCT07797985)
- Testing
- MMH-LAB1 app
- Where
- United Kingdom
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Antidepressants
Discontinuation of Antidepressant Medication in Primary Care.
To investigate the effectiveness of the combination of Supported Protocolized Discontinuation (SPD) and Mindfulness-Based Cognitive Therapy (MBCT) in comparison with SPD alone in successful discontinuation of long-term use of…
- Trial name
- NCT03361514
- Testing
- Supported Protocolized Discontinuation (SPD), Mindfulness Based Cognitive Therapy (MBCT)
- Where
- Netherlands
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Carcinoma, Hepatocellular
Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394)
The purpose of this study is to determine the efficacy and safety of pembrolizumab or placebo given with best supportive care (BSC) in Asian participants with previously systemically treated advanced hepatocellular carcinoma…
- Trial name
- NCT03062358
- Testing
- pembrolizumab, best supportive care (BSC)
- Where
- 41 sites in China, Hong Kong and 3 more
- Volunteers
- 453 people
- Sponsor
- Merck Sharp & Dohme LLC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.