Clinical trials: Supportive Therapy
Parkinson Disease, Parkinsonism
More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease
This is a two-center (University of Colorado, University of California San Francisco) community-based comparative effectiveness study of outpatient palliative care for Parkinson's disease (PD) and related disorders (progressive…
- Conditions
- Parkinson Disease, Parkinsonism, Lewy Body Disease, Supranuclear Palsy, Progressive
- Trial name
- MTMD (NCT03076671)
- Testing
- Palliative Care
- Where
- 2 sites in United States
- Volunteers
- 783 people
- Sponsor
- University of Colorado, Denver
Depression, Depressive Disorder, Major
Feasibility of a Technology-Based Treatment Support System
This study aims to evaluate a technology-based treatment support system for patients undergoing the treatment of depression. The investigators will explore the usefulness of the technology-based treatment support system as an…
- Trial name
- NCT03121937
- Testing
- Mobile App
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Northwestern University
Opioid Use Disorder, Clinical Decision Support
Adaptive Decision Support for Addiction Treatment (ADAPT) Factorial Trial
This study is stage 1 of a larger study which refines and optimizes the EMBED* clinical decision support (CDS; see NCT03658642) to increase number of ED physicians following standard of care for the administration of…
- Trial name
- NCT06793696
- Testing
- Nurse prompt, Provider prompt, Patient facing materials
- Where
- 3 sites in United States
- Volunteers
- 1,129 people
- Sponsor
- Yale University
Edentulous Alveolar Ridge In Mandible, Edentulous Jaw
A Study Comparing Two Different Denture Base Materials in Implant Retained Overdentures
The aim of removable prosthodontics is not only to restore lost oral structures but also to preserve the remaining tissues. Implant-retained overdentures have shown superior outcomes over conventional dentures by reducing…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Edentulous Jaw, Edentulous Mouth, Implant Supported Overdenture
- Trial name
- NCT07271641
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cancer, Quality of Life
Financial Distress in Patients With Advanced Cancer
Advanced cancer has an adverse effect in virtually all dimensions of patients' lives (physical, psychosocial, spiritual, familial, role function).
- Trial name
- DIFIC (NCT01868100)
- Testing
- self-completion questionnaire
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Hospices Civils de Lyon
Heart Failure
Heart Failure Events Reduction With Remote Monitoring and eHealth Support Investigator Initiated Trial
The primary objective of the study is to evaluate the efficacy of a telemedicine-based follow-up strategy compared with usual care in the management of patients with chronic heart failure (HF) at high risk of clinical events.
- Trial name
- HERMeS (NCT03663907)
- Testing
- Telemonitoring
- Where
- Spain
- Volunteers
- 510 people
- Sponsor
- Hospital Universitari de Bellvitge
Stroke, Brain Injuries, Traumatic
Evaluation of a Novel Gait Training Device to Support Body Weight
A novel body weight support device that uses pressurized pants may provide advantages in delivering gait therapy. The objectives of this study are to test the following hypotheses that 1) the novel device will allow for increased…
- Conditions
- Stroke, Brain Injuries, Traumatic, Spinal Cord Injuries, Gait Disorders, Neurologic
- Trial name
- NCT03171207
- Testing
- Lite Run Gait Trainer, Current Harness System
- Volunteers
- 10 people
- Sponsor
- Lite Run Inc.
Cardio-vascular Disease, Depression Disorders
Supporting Patients Starting New Medicines: Evaluating the myCare Start Service in Switzerland
In Phase B, the aim is to evaluate the myCare Start service in routine care within the ambulatory primary care medicine and community pharmacy setting in Switzerland.
- Conditions
- Cardio-vascular Disease, Depression Disorders, Diabetes, COPD
- Trial name
- myCare Start-I (NCT07036471)
- Testing
- myCare Start
- Where
- Switzerland
- Volunteers
- 1,600 people
- Sponsor
- University of Geneva, Switzerland
Intracranial Aneurysm
Safety and Efficacy of the LVIS and LVIS JR Devices in the Endovascular Treatment of Intracranial Aneurysms
A French, multicenter, prospective, observational, "real life" assessment of the safety and efficacy of LVIS and LVIS JR devices in the treatment of intracranial aneurysms
- Trial name
- NCT03553771
- Testing
- LVIS and LVIS JR
- Where
- 20 sites in France
- Volunteers
- 130 people
- Sponsor
- Microvention-Terumo, Inc.
Mental Health, Community Health Workers
Khanya Ekhaya: A Home-Based Intervention
Mental health conditions, such as depression, anxiety, and harmful alcohol use are prevalent among people with chronic diseases, including HIV, and contribute to poor engagement in care.
- Conditions
- Mental Health, Community Health Workers, Training, Global Health
- Trial name
- NCT06985641
- Testing
- Khanya-Ekhaya
- Where
- South Africa
- Volunteers
- 119 people
- Sponsor
- University of Maryland, College Park
Urinary Stones, Prostate Cancer
Development of an AI-Agent for Urological Disease Diagnosis and Treatment
Urological diseases such as urinary stones, prostate cancer, and bladder cancer are very common and often require highly specialized diagnosis and treatment.
- Conditions
- Urinary Stones, Prostate Cancer, Bladder Cancer
- Trial name
- NCT07721935
- Where
- 3 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Resection vs. Best Supportive Care for Hepatocellular Carcinoma (HCC) With Portal Venous Thrombus
The purpose of this study is to evaluate the long-term efficacy and safety of surgical resection compared with best supportive care in patients with resectable hepatocellular carcinoma (HCC) with portal venous thrombus (PVTT) in…
- Trial name
- NCT01600196
- Testing
- Liver resection plus Thrombectomy
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Sun Yat-sen University
Chronic Disease
Model for the Integral Assessment of Chronic Disease Management Supported in Information Technology and Communication.
Controlled and Randomized Clinical trial with 3 parallel groups (intervention group with a health platform NOMHADchronic, phone-based care group, usual care group) developed in the Valencia La Fe Health Department.
- Trial name
- NCT02447562
- Testing
- Platform NOMHADchronic, Phone-based care group, Usual care group
- Volunteers
- 495 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Internet-based Treatment for Depression
Internet Delivered Intervention Program for the Prevention and Treatment of Depression
The purpose of this study is to determine the differential effectiveness of a self applied treatment delivered via Internet for the prevention and treatment of depression, with or without support by the therapist, compared to a…
- Trial name
- NCT02148354
- Testing
- Smiling is Fun
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universitat Jaume I
Detection of Different Prognostic Factors and Their Relation With the Outcome, Using New Protocol to Prove the Role of N-acetyl Cysteine and Adequate Supportive Measures in Aluminum Phosphide Poisoning
Supportive Measures in Treatment of Aluminum Phosphide Poisoning
Aluminum phosphide poisoning (ALP) is a global public health problem, and self-poisoning accounts for one-third of the world's suicide rate.
- Trial name
- NCT03879356
- Testing
- N-acetyl cysteine
- Volunteers
- 44 people
- Sponsor
- Assiut University
Advanced NET of GI Origin, Advanced NET of Lung Origin
Everolimus Plus Best Supportive Care vs Placebo Plus Best Supportive Care in the Treatment of Patients With Advanced Neuroendocrine Tumors (GI or Lung Origin)
The purpose of this study is to compare the antitumor activity of everolimus plus best supportive care versus placebo plus best supportive care in patients with progressive nonfunctional neuroendocrine tumor (NET) of…
- Conditions
- Advanced NET of GI Origin, Advanced NET of Lung Origin, Neuroendocrine Tumors
- Trial name
- RADIANT-4 (NCT01524783)
- Testing
- Everolimus, Best suportive care (BSC)
- Where
- 97 sites in United States, Austria and 23 more
- Volunteers
- 302 people
- Sponsor
- Novartis Pharmaceuticals
Neoplasms
ACS Community Access to Resources Education and Support
The goal of this study is to evaluate the pilot phase of ACS Cares to identify key implementation outcomes and assess effectiveness of the program to improve distress, enhance communication, and reduce missed appointments and…
- Trial name
- ACS CARES (NCT06285929)
- Testing
- ACS CARES Student Navigation
- Where
- 4 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- American Cancer Society, Inc.
Tooth-loss, Edentulous Mouth
Complete Lower Dentures on 1 or 2 Implants
This study is a randomized clinical trial to compare patient satisfaction and prosthetic outcomes with lower dentures retained by one or two implants.
- Conditions
- Tooth-loss, Edentulous Mouth, Complete Denture, Complete Lower Denture
- Trial name
- NCT02117856
- Testing
- 1 implant placed surgically in the mandibular midline, 2 implants placed surgically in the mandibular canine sites, Soft reline (Coe Comfort) of the existing complete lower denture
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Heart Failure, Advanced Heart Failure
REACTION-VAD Trial: Remote Exercise Training Via Telemedicine in Patients With Long-Term Ventricular Assist Devices
Current international guidelines recommend that patients with a heart pump (left ventricular assist device, LVAD) participate in supervised exercise cardiac rehabilitation programs.
- Conditions
- Heart Failure, Advanced Heart Failure, Left Ventricular Assist Device, LVAD
- Trial name
- REACTION-VAD (NCT07611188)
- Testing
- Remote Physical Conditioning Program (Telerehabilitation), Usual care. No Remote Monitoring.
- Where
- 10 sites in Spain
- Volunteers
- 78 people
- Sponsor
- Puerta de Hierro University Hospital
This Study Focus on the Effect of Low-Level Light Therapy on the Amount of Upper Molar Distalization
Assessment of Low Level Laser Therapy Effect on Treatment Outcomes of Bony Supported Distal Jet for Correction of Angle Class II Malocclusion (Randomized Clinical Trial)
The goal of this randomized clinical trial is to compare the effect of LLLT in adolescent patient with class II malocclusion. The main question it aims to answer is: is there a difference in the amount of distalization between…
- Trial name
- LLLT (NCT06170099)
- Testing
- low level laser therapy, bonny supported distal jet
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
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