Clinical trials: Surgery, Cardiovascular
Cardiovascular Diseases
Use of the Quantra QPlus Sytem in Cardiac Surgery
Single center retrospective study evaluating the impact of using the Quantra QPlus System to guide transfusion decisions on postoperative outcomes in patients undergoing cardiac surgery.
- Trial name
- NCT05501730
- Testing
- Quantra QPlus System
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- HemoSonics LLC
Cardiomyopathies
Combined Spinal- Epidural Anesthesia in Patients With Dilated Cardiomyopathy
This study was conducted on 24 patients who have ischemic dilated cardiomyopathy, underwent non cardiac surgery in the lower half of the body under the effect of combined spinal epidural anesthesia at Assiut university hospital.
- Trial name
- NCT03051529
- Testing
- combined spinal epidural anesthesia
- Volunteers
- 24 people
- Sponsor
- Assiut University
Venous Thromboembolism, Embolism and Thrombosis
Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)
The purpose of this study is to determine whether TTP889 prevents venous thromboembolism following surgery to repair hip fracture.
- Conditions
- Venous Thromboembolism, Embolism and Thrombosis, Hip Fractures
- Trial name
- NCT00119457
- Testing
- TTP889
- Where
- 21 sites in Czechia, Denmark and 2 more
- Volunteers
- 300 people
- Sponsor
- vTv Therapeutics
Lung Cancer, Cardiovascular Disease (CVD)
Optimised Lung Cancer Screening to Prevent Cardiovascular and Pulmonary Diseases Coupled With Primary Prevention
This project aims to implement a health prevention program for smokers or former smokers including early detection of lung cancer, cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD).
- Conditions
- Lung Cancer, Cardiovascular Disease (CVD), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SMAC-1 (NCT04315766)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Atrial Fibrillation
Ablation or Surgery for Atrial Fibrillation (AF) Treatment
The purpose of this study is to compare 2 invasive strategies for Atrial Fibrillation treatment, Endocardial catheter ablation isolation of the Pulmonary veins versus minimally invasive thoracoscopic surgical epicardial…
- Trial name
- FAST (NCT00662701)
- Testing
- Catheter Ablation, Surgical Ablation
- Where
- 2 sites in Netherlands, Spain
- Volunteers
- 120 people
- Sponsor
- St. Antonius Hospital
Cardiac Disease
Combined Amiodarone and Electrical Cardioversion for Postoperative Atrial Fibrillation After Cardiac Surgery
To determine the efficacy of cardioversion and amiodarone for cardiac patients who develop postoperative atrial fibrillation
- Trial name
- NCT01558128
- Testing
- Amiodarone, Cardioversion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Weill Medical College of Cornell University
Cardiovascular Diseases
In Silico Trials of Surgical Interventions
The project aims to establish a database of cardiovascular patients using HES and linked mortality data. This database will be used to model trials in silico with the aim of informing the design of future cardiovascular trials in…
- Trial name
- NCT05853536
- Where
- United Kingdom
- Volunteers
- 13,977,257 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Pheochromocytoma, Paraganglioma
Cardiac and Vascular Changes in Pheochromocytoma and Paraganglioma
PHEOCHROMOCYTOMA (PCC)/ PARAGANGLIOMA are catecholamine secreting tumors with varied manifestations. Besides hypertension, PCC patients may have subclinical to overt cardiac and vascular dysfunction, which are important to…
- Conditions
- Pheochromocytoma, Paraganglioma, Cardiovascular Morbidity
- Trial name
- PheoCard (NCT05082311)
- Testing
- Observational study
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Cardiovascular Disease
Family Empathic Behaviour Versus Nurse Empathic Behaviour
The objective was to compare the frequency and intensity of symptoms of anxiety in patients of preoperative cardiac surgery who received empathic behaviour from nurse or family or those who received no specific type of empathic…
- Trial name
- NCT02082951
- Testing
- Empathic behaviour by nurses., Empathic behaviour by family.
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Juliana de Lima Lopes
Hemorrhoid
Posthemorrhoidectomy Pain Management With Electronic Bidet or Sitz Bath
The investigator will perform a randomized clinical trials to compare the effect of pain management and wound healing after hemorrhoidectomy between warm sitz bath and electronic bidet.
- Trial name
- NCT02353156
- Testing
- Electronic bidet, Sitz bath
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Chronic Kidney Diseases, Eye Diseases
Smarter Care Virginia, Examining Low-Value Care in Virginia
Low-value care is defined as patient care that provides no net benefit to patients in specific clinical scenarios, and can cause patient harm.
- Conditions
- Chronic Kidney Diseases, Eye Diseases, Cardiac Disease, Surgery
- Trial name
- NCT04053335
- Testing
- Multicomponent Physician Performance Peer-Comparison Feedback Intervention
- Where
- United States
- Volunteers
- 5,000,000 people
- Sponsor
- University of California, Los Angeles
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG
This study is planned to check the effect of holy Quran recital on the development of delirium after conronary artery bypass graft surgery (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft Surgery, Delirium, Postoperative
- Trial name
- NCT06346990
- Testing
- Holy Quran Recital
- Volunteers
- 264 people
- Sponsor
- Applied Science Private University
Ventricular Septal Defect, Complete Atrioventricular Canal
Optical Tissue Identification for Myocardial Architecture
The goal of this study is to test the hypothesis that fiberoptic confocal microscopy (FCM) imaging during repair of common congenital heart defects is a useful adjunct for avoidance of conduction abnormalities.
- Conditions
- Ventricular Septal Defect, Complete Atrioventricular Canal, Tetralogy of Fallot With Pulmonary Stenosis
- Trial name
- OPTIMA (NCT04017975)
- Testing
- Fluorescite, Cellvizio 100 Series System with Confocal Miniprobes
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Aditya Kaza
Coronary Artery Disease, CABG
Clinimetric Properties of Performance Based Functional Outcome Measure After (CABG) Surgery
The purpose of this research is to determine which performance based functional outcome test among Time up and go test, Five times sit to stand test, 2 minute walk test and 6 minute walk test has the greatest significance in…
- Trial name
- NCT07060937
- Testing
- Physiotherapy Protocol
- Where
- 2 sites in Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Aortic Dissection
Nordic Consortium for Acute Type A Aortic Dissection-2
The Nordic Consortium for Acute Type A Aortic Dissection-2 (NORCAAD-2) is a multicenter research collaboration involving up to 19 units in the Nordic countries and one in The Netherlands.
- Trial name
- NORCAAD-2 (NCT06862583)
- Testing
- surgery, endovascular intervention
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Karolinska Institutet
Acute Coronary Syndrome
Effect of Glucose-insulin-potassium Solution on Myocardial Protection During Off-pump Coronary Bypass Surgery in Patients With Acute Coronary Syndrome
Patients undergoing multivessel off-pump coronary bypass surgery (OPCAB) inevitably experience cumulative ischemia-reperfusion injury at myocardium.
- Trial name
- NCT01384656
- Testing
- GIK solution
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Congenital Heart Disease, Coronary Artery Anomaly
European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries
Anomalous aortic origin of a coronary artery (AAOCA) is a group of rare congenital heart defects with various clinical presentations.
- Conditions
- Congenital Heart Disease, Coronary Artery Anomaly, Sudden Cardiac Death, Surgical Procedure, Unspecified
- Trial name
- EUROAAOCA (NCT06089902)
- Testing
- unroofing or other surgery if needed
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 500 people
- Sponsor
- University of Padova
Sleep, Atrial Fibrillation
Impact of Sleep Quality on Outcomes After Cardiac Surgery
Sleep is a basic human need and is essential for good quality of life, good health. In fact, humans spend one third of their life time in sleeping or attempting to do so.
- Conditions
- Sleep, Atrial Fibrillation, Delirium, Postoperative, Complications, Postoperative
- Trial name
- NCT06527105
- Testing
- Eye masks and ear plugs
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amrita Institute of Medical Sciences & Research Center
Coronary Artery Disease, Multivessel Coronary Artery Disease
Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery
The study objective is to compare standard CABG to a hybrid revascularization strategy (RA-MIDCAB + PCI) in patients who have multi-vessel CAD and an indication for surgery, but who have a slightly higher risk of post-operative…
- Trial name
- ROBOT RCT (NCT06378775)
- Testing
- Coronary Artery Bypass Graft, Robotically-assisted minimally-invasive direct coronary artery bypass, Percutaneous Coronary Intervention
- Volunteers
- 80 people
- Sponsor
- Cardiology Research UBC
Atrial Fibrillation
Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery
In this study, the investigators aim to determine whether injecting botulinum toxin into epicardial fat pads is efficacious and safe for decreasing postoperative atrial fibrillation (POAF) after cardiac surgery.
- Trial name
- NCT02498769
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Joseph Mathew, M.D.
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