Clinical trials: Surgery, Dental
Postoperative Pain
Efficacy of EXPAREL in Comparison to Standard of Care for the Treatment of Post Operative Dental Implant Pain
This study is researching managing postsurgical pain by injecting both short-acting local anesthetics and EXPAREL® at the time of surgery and reviewing if it could reduce or eliminate the need for postsurgical opioids and improve…
- Trial name
- FAST (NCT02533440)
- Testing
- EXPAREL and Local Anesthetics, Oral Opioid and Local Anesthetics
- Where
- 3 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Bellaire Facial Surgery Center
Impacted Third Molar Tooth
Perineural and Systemic Dexamethasone Use in Dental Surgeries in Terms of Anesthesia Duration and Postop Complaints
Participants will be asked to use some medications after the tooth extraction procedure. These drugs can be used in different ways.
- Trial name
- NCT06318013
- Testing
- vitality test
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Implant Infection, Bone Loss
The Effect of Chlorohexidine Gel on Tissue Healing Following Surgical Exposure of Dental Implants
The aim of this study is to evaluate the healing of peri-implat tissue following surgical uncovering with the adjunctive use of Chlorohexidine (CHX) gel.
- Trial name
- NCT03195582
- Testing
- Corsodyl
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Jaw, Edentulous, Partially
Implant Retained Rehabilitation With Surgical and Prosthetic Digital Workflow
The aim of this study is to prospectively collect clinical data to confirm the safety and clinical performance of Neodent Titanium Base Abutment and Pro PEEK Abutment in daily dental practice setting, by means of a randomized…
- Trial name
- NCT04066309
- Testing
- Neodent GM Helix Implant, GM Customizable Healing Abutment, GM Pro PEEK Abutment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Neodent
Sinus; Dental, Implant Complication
Evaluation of the Efficacy of Allograft Versus Tenting Technique in Open Sinus Lifting With Immediate Implant Placement
Implant placement in deficient posterior maxilla is a challenging clinical situation that necessitates appropriate treatment options to restore this area.
- Conditions
- Sinus; Dental, Implant Complication, Surgery-Complications
- Trial name
- NCT06254378
- Testing
- Sinus lifting with allograft, Sinus lifting without graft
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Photobiomodulation, Endodontic Disease
Effect of Photobiomodulation to Reduce Post-operative Pain After Endodontic Surgery
The objective of this study will be to evaluate if photobiomodulation (FBM) can reduce postoperative pain in patients who will undergo endodontic surgery.
- Conditions
- Photobiomodulation, Endodontic Disease, Pain, Inflammation
- Trial name
- NCT05935306
- Testing
- Ibuprofen, Photobiomodulation simulation, Photobiomodulation
- Where
- Uruguay
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dental Implantation
Accuracy of Guided Implant Placement Using Double Versus Triple Scan Protocol in Completely Edentulous Patients
16 implant placement by surgical guide using double scan protocol versus triple scan protocol to Evaluate angular and linear deviation of virtual implants and actual implant position in completely edentulous patients according to…
- Trial name
- NCT03321162
- Testing
- scan protocol
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Opioid Use Disorders, Tooth Extraction Status Nos
Opioid Analgesic Use and Disposal Following Outpatient Dental Surgery
Background: Overdose deaths from prescription opioid analgesics quadrupled from 4,000 cases to nearly 17,000 cases annually during 1999-2011.
- Trial name
- NCT02814305
- Testing
- Financial, Educational
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Effectiveness of Microscope During Apical Surgery in Endodontic Treated Teeth.
RCT: Effectiveness of a Microscope During Dental Root Apical Surgery
An endodontic treatment is the standard therapy for teeth with periapical periodontitis. The overall success rate for this treatment is high; 97% of the treated teeth are retained in the oral cavity after 8 years (Salehrabi \&…
- Trial name
- NCT01759069
- Testing
- Surgical treatment with microscope
- Where
- Netherlands
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Post-Op Complication, Endodontic Inflammation
Postoperative Pain After Using NiTi Instruments
The aim of this randomized clinical trial was to compare the incidence, intensity and duration of postoperative pain following the removal of root canal obturation materials canals using rotary (ProTaper Universal or Hyflex EDM)…
- Conditions
- Post-Op Complication, Endodontic Inflammation, Endodontically Treated Teeth, Apical Periodontitis
- Trial name
- NCT04700995
- Testing
- NiTi instruments
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Trakya University
Pain, Postoperative
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered…
- Trial name
- NCT04790812
- Testing
- Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Dental Pain
A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
Researchers are looking for a better way to relieve pain in people, such as after dental surgery. Participants in this study, have had 3 or 4 third molars (cheek teeth) removed and subsequently have moderate to severe tooth pain.
- Trial name
- NCT05485805
- Testing
- Naproxen sodium and caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Bayer
Implant Therapy
Dental Implant Placement in Adjunction With Autologous Alveolar Bone-Marrow Derived Mesenchymal Stem Cells (aBM-MSCs)
Systemically healthy volunteers with no active periodontal disease are recruited from referrals to the Dept. of Preventive Dentistry, Periodontology and Biology of Implants, Aristotle Univ of Thessaloniki for implant therapy.
- Trial name
- Implant_bone (NCT03070275)
- Testing
- Biocomplex: aBM-MSCs/fibrin glue/collagen fleece, Two-stage surgical implant placement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Personalized Musical Intervention
Effect of Music on Burden of Dental Implant Surgery
Personnalized music can decrease the burden of care. This experimental clinical trial examines the effect of personalized musical intervention on the burden of dental implant surgery.
- Trial name
- NCT04099264
- Testing
- Personalized music, Audio Books
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Surgery, Computer-Assisted, Dental Implants
The Double Factor Technique: a Computer-guided Implant Surgery Technique for Fully Edentulous Patients
To overcome the limitations of the current dynamic and static Computer Assisted surgery protocols in fully edentulous patients, and combine the advantages of both approaches, a new technique has been developed, referred to as the…
- Trial name
- DoubleFactor (NCT05512845)
- Testing
- Double Factor technique
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Adrià Jorba García
Dental Education and Teaching Learning Processes, Psychomotor Skill Learning
Motor Learning Approaches in Periodontal Treatment Education
This study aims to evaluate the effectiveness of different motor learning approaches in preclinical non-surgical periodontal treatment education among dental students.
- Conditions
- Dental Education and Teaching Learning Processes, Psychomotor Skill Learning, Periodontal Education
- Trial name
- MLSPT (NCT07672080)
- Testing
- Implicit Learning With Standard Training, Implicit Learning With Extended Training, Implicit Learning With Distributed Training
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Anxiety, Dental, Post Operative Pain
Effectiveness of Green Color Exposure on Dental Anxiety
The investigator's aim in this study was to evaluate the preoperative anxiety and the pain felt during the operation due to exposure to green light.
- Trial name
- NCT05584696
- Testing
- Green light exposure, Normal light exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Drug Effect, Tooth Extraction
Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia
In the complexity of the Dental care the third molar surgery is one of the most common procedures, it is indicated for multiple reasons like infections in root canal, prosthetics or even esthetical purposes.
- Trial name
- ECA (NCT04166890)
- Testing
- Articaine / EPINEPHrine Cartridge
- Where
- Colombia
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Dental Implant
Accuracy of Dental Implant Placement Using a Collaborative Surgery Robot
For free hand dental implant placement, a key difficulty is to accurately control the position. Improving precision of dental implant placement is considered important for safety and efficacy of tooth replacement with dental…
- Trial name
- NCT05919862
- Testing
- Robot system, Freehand surgery
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Acute Pain
Epigenetic Influences on Post-Surgical Acute and Chronic Pain
Pain is the way our brain interprets certain bodily sensations. It is very difficult to describe or to put into words as perception and tolerance of pain varies widely between individuals.
- Trial name
- NCT02002520
- Where
- 2 sites in Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong