Clinical trials: Surgery, Dental
Tooth Loss, Partial Edentulism
Single _ Drill Vs Full Sequence Guided Implant Placement
This randomized clinical trial aims to compare the accuracy of single-drill (pilot-guided) computer-guided implant surgery versus full-sequence computer-guided dental implant placement.
- Trial name
- NCT07737197
- Testing
- Full-sequence computer-guided dental implant placement., Single-drill computer-guided dental implant placement
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Cairo University
Edentulous Alveolar Ridge, Edentulous Alveolar Ridge Atrophy
Freeze-dried Bone Allograft vs Autologous Bone Blocks in the Lateral Augmentation of the Jaws
After tooth loss, the alveolar ridge undergoes various modeling and remodeling processes, resulting in overall bone resorption. In case of extensive alveolar atrophy, bone volume must be restored before or during implant…
- Trial name
- NCT07104370
- Testing
- Bone augmentation using an autologous bone block, Bone augmentation using freeze-dried allograft block, preoperative cone beam computed tomography (CBCT)
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- Semmelweis University
Periodontitis
Effect of Smoking Cessation on Non-surgical Periodontal Therapy
The aim of this prospective study is to verify the efficacy of smoking cessation on non-surgical periodontal therapy in adult subjects with chronic periodontitis.
- Trial name
- EsCAPE (NCT02493270)
- Testing
- Smoking cessation therapy, Non-surgical periodontal therapy
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Partial Edentulism Class 1 or Class 2
Comparative Evaluation of Artificial Intelligence-Assisted Versus Conventional Guided Implant Planning in Free End Saddle Cases
This study aims to compare the accuracy and clinical performance of artificial intelligence (AI)-assisted implant planning with conventional human-based implant planning in patients presenting with free-end saddle edentulous…
- Trial name
- NCT07891442
- Testing
- Dental implant palcement
- Volunteers
- 20 people
- Sponsor
- Mariam Morcos Nasr
Post Operative Hemorrhage
Direct Oral Anticoagulants and Management of Blleding Following Dental Extractions. A Prospective Cohort Study.
Evaluation of DOACs treatment on post-extraction bleeding
- Trial name
- DOACS_1 (NCT06365242)
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Pisa
Jaw, Edentulous
Evaluation of Treatment With Fixture Microthread™ in Patients Missing All Teeth in the Upper Jaw, When Using One-Stage Surgery
The primary objective of the study is to evaluate the long-term survival rate of implants and prostheses when treating totally edentulous upper jaws with Fixture MicroThread (Micro-Macro) using a one-stage surgical procedure.
- Trial name
- NCT00748397
- Testing
- Fixture MicroThread (Micro-Macro)
- Where
- 4 sites in United States, Germany and 2 more
- Volunteers
- 54 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Surgical Operation With Implant of Artificial Internal Device
A Non-Interventional Study to Document the Use of Straumann BLX Implants in Daily Dental Practice
Prospective, multi-center, non-interventional observation to document the success and survival rates of Straumann BLX Implants used for tooth replacement in cleared indications up to 1 year after implant placement
- Trial name
- BLX_NIS (NCT03613077)
- Testing
- surgical placement of an endosteal implant
- Where
- Germany
- Volunteers
- 153 people
- Sponsor
- Institut Straumann AG
Postoperative Pain
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
- Trial name
- NCT00092300
- Testing
- MK0966, rofecoxib, Comparator: valdecoxib
- Volunteers
- 450 people
- Sponsor
- Merck Sharp & Dohme LLC
Periodontal Disease, Periodontal Surgery
Serum Inflammatory Protein Concentration During Dental Treatment
The goal of this observational study is to study the molecular markers of stress in blood samples from people who are having periodontal surgery.
- Trial name
- NCT07468929
- Testing
- Blood samples for inflammatory markers, periodontal surgery, Periodontal maintenance
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Skeletal Class III Malocclusion
Surgery-First Orthognathic Surgery in Skeletal Class III Treatment
This study evaluates the efficacy and stability of the "Surgery-First" approach (SF approach) in treating patients with skeletal Class III malocclusion, utilizing a combined retrospective and prospective data collection method.
- Trial name
- NCT07433842
- Testing
- Surgery-First Orthognathic Surgery
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Hanoi Medical University
Postoperative Dental Pain
A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
Researchers are looking for a better way to relieve pain in people, such as after dental surgery. Participants in this study, have had 3 or 4 third molars (cheek teeth) removed and subsequently have moderate to severe tooth pain.
- Trial name
- NCT05485805
- Testing
- Naproxen sodium and caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Bayer
Peri-implantitis
Surgical and Non-surgical Treatment of Peri-implantitis
This study will compare surgical and non surgical treatments of peri-implantitis. Peri-implantitis is an inflammation around dental implants that can lead to the loss of the implant over time if no treatment is established.
- Trial name
- Perio-implants (NCT02241577)
- Testing
- Surgical treatment, Non-surgical treatment
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of Rio Grande do Sul
Oral Surgical Procedures, Surgery, Oral
Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Anxious Patients
Whether patient-maintained sedation (the patient controls his/her degree of sedation using a hand-held device) using the drug propofol is safer and more effective when using deteriorating reaction time as an added safeguard…
- Conditions
- Oral Surgical Procedures, Surgery, Oral, Dental Anxiety, Surgery
- Trial name
- NCT00355693
- Testing
- Pump for propofol delivery
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Glasgow
Pain, Acute
Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
The purpose of this study is to evaluate the analgesic effects of cannabidiol for patients who have undergone simple tooth extraction.
- Trial name
- SWAP (NCT04271917)
- Testing
- cannabidiol, acetaminophen 500mg and ibuprofen 200mg combo
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Tennessee
Type 2 Diabetes Mellitus, Periodontitis
Oral Health Policy for Patients With Type 2 Diabetes Mellitus in Chile: A Microsimulation Model Based on Real-world Data
The goal of this study is to evaluate the cost-effectiveness of the current proposal and different decision-making scenarios of periodontal care coverage increases for patients with T2DM in Chile.
- Conditions
- Type 2 Diabetes Mellitus, Periodontitis, Diabetic Complication, Dental Care
- Trial name
- NCT05809817
- Testing
- Periodontal treatment
- Where
- 2 sites in Chile
- Volunteers
- 135 people
- Sponsor
- University of Chile
Early Childhood Caries
Oral Health Intervention for Caregivers of Children Presenting for Dental Surgery
Too many young children, particularly those living in poverty, present for dental surgery under anesthesia - an expensive, potentially dangerous, short-term fix that often results in recurring oral health disease and subsequent…
- Trial name
- PROTECT (NCT07220850)
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- University of Illinois Chicago
Postoperative Pain
Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial
This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery.
- Trial name
- NCT07413055
- Testing
- Dexamethasone 4 Mg/mL Injectable Solution, Dexamethasone 8Mg Solution for Injection
- Where
- Oman
- Volunteers
- 138 people
- Sponsor
- Oman Ministry of Health
Edentulous Alveolar Ridge In Mandible
Clinical Effects of Keratinized Mucosa Augmentation Around Dental Implant With Free Gingival Graft in Different Surgical Timing at Mandibular Posterior Sites
This study aims to compare clinical outcomes and tissue stability at implant sites in the mandibular posterior region with insufficient buccal keratinized gingiva.
- Trial name
- NCT07088172
- Testing
- free gingival grafts during the second stage of implant surgery, free gingival grafts prior to the implantaion
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Surgery, Computer-Assisted, Dental Implants
The Double Factor Technique: a Computer-guided Implant Surgery Technique for Fully Edentulous Patients
To overcome the limitations of the current dynamic and static Computer Assisted surgery protocols in fully edentulous patients, and combine the advantages of both approaches, a new technique has been developed, referred to as the…
- Trial name
- DoubleFactor (NCT05512845)
- Testing
- Double Factor technique
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Adrià Jorba García
Dental Anxiety, Impacted Third Molar Tooth
Anxiety Control by Erythrina Mulungu
This study evaluated the effectiveness of the Erythrina mulungu in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT01948622
- Testing
- Mulungu
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liane Maciel de Almeida Souza