Clinical trials: Surgery With General Anesthesia
Postoperative Sore Throat
Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
The aim of this study is to compare the efficacy of nebulized ketamine versus nebulized magnesium sulfate in reducing the incidence and severity of POST. Primary outcome To compare the incidence of POST method.
- Trial name
- NCT07381036
- Testing
- Ketamine nebulizer, Mg sulfate nebulizer
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
General Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia
To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous [IV] slow injection over 30 [±5] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection…
- Trial name
- NCT05478174
- Testing
- HSK3486, Propofol
- Where
- 23 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Caudal Block, Pediatric Urologic Surgeries
Comparison of Caudal Block Combined With General Anesthesia and Penile Block and Intravenous Fentanyl in Pediatric Surgeries
Urogenital surgery is one of the most frequently performed surgical procedures in the pediatric patient population. There is no consensus on which analgesic method is most effective for pain control in these patients.
- Conditions
- Caudal Block, Pediatric Urologic Surgeries, Fentanyl, Pediatric Delirium
- Trial name
- NCT06862271
- Testing
- Group 1 ( Caudal block group ), Group 2 (Penile block and IV Fentanyl group)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Miray Gözde Özdemir
Strabismus
The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.
Determine whether the application of povidone-iodine ophthalmic solution onto the ocular surface causes a change in respiration in children undergoing strabismus surgery with general anesthesia.
- Trial name
- NCT03349515
- Testing
- Provodine-Iodine Solution, Group B will receive three drops in each eye of ophthalmic balanced salt solution.
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Urologic Diseases
Effect of Prewarming During Induction of General Anesthesia Combined With Warmed Intravenous Fluid on Core Temperature.
Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming during induction of general anesthesia during urologic surgery.
- Trial name
- NCT05636189
- Testing
- warming during induction of anesthesia, Prewarmed intravenous fluid administration
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Inje University
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Postoperative Complication, Cognitive Retention Disorder
Methylprednisolone Combined Electric-acupuncture on Cognitive Function
Postoperative cognitive dysfunction (POCD) refers to the patients in the central nervous system complications after general anesthesia and clinical manifestations of mental disorder, anxiety, personality changes, impaired memory…
- Trial name
- NCT02535039
- Testing
- Methylprednisolone, Physiological saline
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Supraglottic Airway Devices
Respiration and The Airway With Laryngeal Masks
Baska® mask (Proact Medical Systems, Frenchs Forest NSW, Australia) is displayed in figure 1 which is the latest addition to an array of supra-glottic airway devices in clinical use.
- Trial name
- NCT03542890
- Testing
- Baska Mask, I-gel
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Post-Op Complication, Pain, Postoperative
TAP Block On Abdominal Surgery Patients With General Anesthesia
INTRODUCTION: The aim of this study was to investigate the effects of tranversus abdominis plane (TAP) block placed postoperatively using ultrasound guidance for patients with caesarean section, myomectomy and hysterectomy under…
- Trial name
- TAPBLOCK (NCT04364477)
- Testing
- transversus abdominis plane (TAP) block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University Hospital
Combination of General Anesthesia to Spinal and Epidural Techniques
Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results.
- Trial name
- NCT05301127
- Testing
- spinal-epidural device
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Analgesics，Opioid, Bariatric Surgery
Multimodal Analgesic Management of Naborphine Combined With Opioid Free Anesthesia in OSA Patients Undergoing Bariatric Surgery
Comparative study to explore the effect of opioid free anesthesia technology in perioperative analgesia management, clarify the effect of naborphine instead of opioids on perioperative analgesia management in morbid obesity…
- Trial name
- NCT05386979
- Testing
- Opioid free anesthesia technology
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Healthy
I-Gel Versus Disposable Laryngeal Mask (LMA) for General Anesthesia (GA) With Controlled Ventilation
Randomized controlled trial comparing performance of the I-gel and disposable Laryngeal Mask Airways under controlled ventilation. 200 patients, 100 in each arm. Measurement of peak airway and sealing pressures.
- Trial name
- IGE(L)MA (NCT00668278)
- Testing
- Insertion of laryngeal mask airway (AuraOnce mask), Insertion of I-gel airway, Measurement of airway pressures
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northern Health and Social Care Trust
Cystoscopes, Baxter Anaesthesia Brand of Desflurane
Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery
This is a single-center, prospective, randomized, double-blind, double-arm trial including 68 subjects scheduled to undergo urological cystoscope surgeries under general anesthesia (GA) with intubation through a laryngeal mask…
- Conditions
- Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
- Trial name
- NCT01219881
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Hip Fractures, COVID-19
Anesthesia Technique in COVID-19 Positive Hip Fracture Patients
Patients with COVID undergoing hip fracture repair have high mortality rates. If spinal anesthesia is associated with decreased rates of mortality, this study could provide hypothesis generating data for prospective studies.
- Conditions
- Hip Fractures, COVID-19, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT05133648
- Testing
- Hip Fracture Surgery, COVID-19 infection
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Facial Plane Blocks
Comparison of the Efficacy of One Level and Tow Level of Bilateral Thoracic Erector Spinae Plane Block Combined With General Anesthesia in Laparoscopic Bariatric Surgery for Obese Patients: Randomized Controlled Trial
comparison of the feasibility and efficacy of the one-level and two-level thoracic ESP block and their effect on intraoperative and postoperative analgesia in bariatric surgeries.
- Trial name
- NCT06811493
- Testing
- bilateral thoracic erector spinae plane block combined with general anesthesia in laparoscopic bariatric surgery in obese patients
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Morbid Obesity, Bariatric Surgery
Study to Determine Incidence of Hypoventilation in Patients Who Have Undergone Gastric Bypass
The purpose of this study is to determine if gastric bypass patients experience hypoventilation in the immediate postoperative period, and to what degree.
- Trial name
- NCT00316446
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Drug Use
Regional Nasal Block and Dexmedetomidine in Endoscopic Sinus Surgery
The purpose is to compare the efficacy of combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery in optimizing intraoperative surgical field.
- Trial name
- NCT05361642
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Laparoscopic Surgery, PONV
Effects of Auricular Acupressure on the Management of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgeries
Auricular acupressure is easily accessible and easily performed, and can significantly relieve PONV symptoms, and improve patient's satisfaction in women receiving general anesthesia for gynecological surgeries.
- Conditions
- Laparoscopic Surgery, PONV, Auricular Acupressure
- Trial name
- NCT05540236
- Testing
- auricular acupressure
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Anxiety, Postoperative Pain
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
This prospective randomized controlled study aims to evaluate the anxiolytic effect of preoperative sublingual melatonin and its impact on postoperative pain scores when administered in two different doses to female patients…
- Conditions
- Anxiety, Postoperative Pain, Anesthesia
- Trial name
- NCT06997263
- Testing
- Melatonin 3 mg Sublingual, Melatonin 6 mg Sublingual
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Benha University
Pulmonary Embolism
The Clinic Study to Prevent Pulmonary Embolism in Patients With General Anesthesia Operation in Perioperative Period
The purpose of this study is to investigate the prevention of Pulmonary Embolism in Patients who With General Anesthesia Operation in Perioperative Period.
- Trial name
- NCT02460952
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital