Clinical trials: Surgery for Colorectal Cancer.
Colorectal Cancer, Primary Peritoneal Cavity Cancer
Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer
RATIONALE: Drugs used in chemotherapy, such as leucovorin, fluorouracil, and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00769405
- Testing
- fluorouracil, leucovorin calcium, oxaliplatin
- Where
- 20 sites in France
- Volunteers
- 264 people
- Sponsor
- UNICANCER
Morbid Obesity, Hernia
Minimally Invasive Surgery (MIS) Database for the Purpose of Research
The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD.
- Conditions
- Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
- Trial name
- NCT00535990
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Colon Neoplasms
AI-Assisted Microbiome Analysis for Evaluating the Efficacy of MPRO3 and Gut Environmental Changes in Colon Cancer Surgery Patients
The goal of this clinical trial is to evaluate the effects of MPRO3(probiotics mixture) supplementation on surgical outcomes and gut health in patients undergoing surgery for colon cancer.The main question is whether MPRO3…
- Trial name
- AI-MPRO3 (NCT07792980)
- Testing
- MPRO3
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- hy Co., LTD.
Adenocarcinoma of the Rectum, Adenocarcinoma
Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks
The aim of this study is to determine whether greater rectal cancer downstaging and regression occurs when surgery is delayed to 12 weeks after completion of radiotherapy/chemotherapy compared to 6 weeks.
- Conditions
- Adenocarcinoma of the Rectum, Adenocarcinoma, Adenocarcinoma, Mucinous, Carcinoma
- Trial name
- NCT01037049
- Testing
- Patients who have surgery at 12 weeks after radiotherapy/chemoradiotherapy
- Where
- 23 sites in Brazil, Canada and 2 more
- Volunteers
- 237 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Fracture of Surgical Neck of Humerus, Colonic Tumor
An Algorithm for Intra-operative Goal-directed Haemodynamic Management in Non-cardiac Surgery
A systematic literature search a goal-directed haemodynamic algorithm was created. The hypothesis of this study was that the goal-directed haemodynamic algorithm is feasible and can improve clinical outcome.
- Conditions
- Fracture of Surgical Neck of Humerus, Colonic Tumor, Stage IIIB Ovarian Carcinoma, Neoplasm of Head of Pancreas
- Trial name
- ERAS_feasi (NCT01384097)
- Where
- Germany
- Volunteers
- 774 people
- Sponsor
- Charite University, Berlin, Germany
Rectal Cancer, Adenocarcinoma
Comparison Between Tailored Surgery Versus Total Mesorectal Excision in ycT2-3N0M0
The purpose of this study is to show that tailored treatment based on local excision can expand the target of non-radical treatment in ycT2-3N0M0 patients after neoadjuvant chemoradiotherapy for low rectal cancer and that the…
- Trial name
- NCT05164315
- Testing
- Tailored surgery, Total mesorectal excision (TME)
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Seoul National University Hospital
Rectal Neoplasms, Sexual Dysfunction
Robotic Versus Laparoscopic Low Anterior Resection for Rectal Cancer
Prospective randomized trial comparing robotic versus laparoscopic Low anterior resection for rectal cancer. Primary endpoint: Compare urinary dysfunction between robotic and laparoscopic approach.
- Conditions
- Rectal Neoplasms, Sexual Dysfunction, Urinary Incontinence, Quality of Life
- Trial name
- RAR (NCT03209076)
- Testing
- Robotic, Laparoscopic
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Rectal Neoplasms, Rectal Cancer Stage II
Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer
Preoperative 5-FU-based (5-fluorouracil) chemoradiotherapy (CRT), total mesorectal excision surgery, and 4 cycles of adjuvant 5-FU - as established by CAO/ARO/AIO-94 - is at present a standard of care for patients with locally…
- Conditions
- Rectal Neoplasms, Rectal Cancer Stage II, Rectal Cancer Stage III
- Trial name
- CAOAROAIO-12 (NCT02363374)
- Testing
- Induction Chemotherapy arm A, Radiation arm A, Radiation arm B
- Where
- 20 sites in Germany
- Volunteers
- 311 people
- Sponsor
- Prof. Dr. med. Claus Rödel
Surgery, Colorectal Cancer
Postoperative Electrical Muscle Stimulation Two
Undesirable loss of skeletal muscle mass (atrophy) is a common feature of many diseases as well as ageing, bed rest and physical inactivity.
- Conditions
- Surgery, Colorectal Cancer, Muscle Atrophy, Cancer Gi
- Trial name
- POEMS2 (NCT06964438)
- Testing
- Neuromuscular Electrical Stimulation, Protein supplement drink
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Nottingham
Peritoneal Carcinomatosis, Colon Cancer
Metachonous Peritoneal Carcinomatosis Incidence After Curative Surgery for pT4 Colon Cancer Patients
This is an observational retrospective cohort study to determine metachronous peritoneal carcinomatosis in a specific subgroup of colon cancer patients, those with a final pathologic exam corresponding to pT4 tumors.
- Trial name
- NCT05300789
- Testing
- Follow-up
- Where
- Spain
- Volunteers
- 1,152 people
- Sponsor
- Carlos Cerdán Santacruz
Rectal Cancer
A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradiation Therapy (CCRT)
This is a three-year research project. The major aims of this study are to:(1) compare the functional recovery and oncologic results in patients with advance rectal cancer treated by either traditional open or laparoscopic…
- Trial name
- NCT00601549
- Testing
- Laparoscopic surgery, Traditional open surgery
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Metastatic Colorectal Cancer, Circulating Tumor DNA
ctDNA in CRC Patients Undergoing Curative-intent Surgery for Liver Metastases
This is a prospective multicenter cohort study, was designed to explore the prognostic value of ctDNA as a biomarker of disease response and recurrence or death in patients undergoing curative-intent surgical resection of…
- Trial name
- CLIMES (NCT05787197)
- Where
- 16 sites in France
- Volunteers
- 232 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Colorectal Cancer, Rectal Tumors
Reconstruction Techniques and Vascular Approach After Laparoscopic Left Hemicolectomy and Rectum Low Anterior Resection
This is an interventional, controlled and randomized single-center clinical trial with patients diagnosed with colorectal cancer that will undergo laparoscopic left hemicolectomy or laparoscopic low anterior resection for rectal…
- Trial name
- TAHR (NCT02746224)
- Testing
- Initially dissection of inferior mesenteric vein, Initially dissection of inferior mesenteric artery, Latero-terminal colorectal anastomosis
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Colorectal Cancer
Effectiveness of Gum Chewing on Ileus in Chinese Colorectal Patients Underwent Laparoscopic Colorectal Surgery
Gum chewing group will have less ileus and early resume of bowel motion than control group.
- Trial name
- NCT02419586
- Testing
- bubble gum
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Shum Nga Fan
Colon Adenocarcinoma
Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study
This trial evaluates how inhalational anesthesia (drawn in through the lungs) and total intravenous anesthesia (TIVA) (through a needle in a vein in the arm) change the body's ability to recover from surgery or whether they…
- Trial name
- NCT06017141
- Testing
- Biospecimen Collection, Electronic Health Record Review, Fentanyl Citrate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Kansas Medical Center
Colorectal Neoplasms
Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis
The Bev-IP trial is designed to assess the feasibility and efficacy of a combined treatment consisting of perioperative combination chemotherapy with the vascular endothelial growth factor A inhibitor bevacizumab and…
- Trial name
- NCT02399410
- Testing
- perioperative chemotherapy plus bevacizumab, cytoreductive surgery, Intraperitoneal Oxaliplatin
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Colorectal Cancer, Surgery-Complications
Early Discharge After Robotic Colorectal Surgery (eRCS): a Prospective Observational Study
The enhanced recovery after surgery (ERAS) scheme has improved recovery of patients by addressing the surgical stress and enabling a proactive perioperative care which has proven to decrease postoperative complications and reduce…
- Trial name
- eRCS (NCT05408182)
- Testing
- Robotic colorectal resection with ERAS (or eRCS) perioperative care
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ospedale di Camposampiero
Colorectal Liver Metastasis
Minimally Invasive Versus Open Liver Resection for Patients With Colorectal Cancer Liver Metastases
To examine survival of patients who underwent minimally invasive versus open liver resection for colorectal cancer with liver metastases.
- Trial name
- NCT03895723
- Testing
- laparoscopic and robotic liver resection, open surgery
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xu jianmin
Colorectal Cancer
Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colon Cancer That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as fluorouracil, leucovorin, and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00321828
- Testing
- bevacizumab, fluorouracil, leucovorin
- Where
- 163 sites in United States
- Volunteers
- 90 people
- Sponsor
- NSABP Foundation Inc
Colonic Neoplasms Malignant, Cecal Neoplasms
Local Cecal Cancer - Optimization of Surgical Treatment
The purpose of this study is to determine the clinical efficacy, safety, and oncologic outcomes of ileocecal resection (ICR) with D3 lymphadenectomy compared to standard right hemicolectomy(RHC) for cecal cancer.
- Trial name
- LoCCOSTe (NCT06121089)
- Testing
- ileocecal resection with extended D3 lymphadenectomy., Right hemicolectomy with D3 lymphadenectomy.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Moscow Clinical Scientific Center