Clinical trials: Surgery for Primary Lung Cancer, open to volunteers
Lung Cancer (NSCLC)
Percutaneous Pulsed Electric Field Ablation for Early-Stage NSCLC and Lung Oligometastases: A Safety and Efficacy Study
The goal of this observational study is to evaluate the performances of a percutaneous Pulsed Electrical Field (PEF) ablation to treat patients with primary early-stage lung cancer (NSCLC) or lung oligometastatic Tumors who are…
- Trial name
- NCT07799194
- Testing
- Pulsed Electric Field Ablation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Energenx Medical LTD.
Multiple Primary Lung Cancers
Video-Assisted Thoracoscopic Surgery Combined With Radiofrequency Ablation Versus VATS Alone for Multiple Primary Lung Cancer
This multicenter randomized controlled trial will compare two surgical approaches for patients with synchronous ipsilateral multiple primary lung cancer, meaning two or more primary lung cancers diagnosed at the same time in the…
- Trial name
- NCT07819669
- Testing
- Video-Assisted Thoracoscopic Resection of the Main Lesion, Intraoperative CT-Guided Radiofrequency Ablation of the Secondary Lesion, Video-Assisted Thoracoscopic Sublobar Resection of the Secondary Lesion
- Where
- 3 sites in China
- Volunteers
- 160 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NSCLC Stage IV
Primary Tumor Resection With EGFR TKI for Stage IV NSCLC
Our project is going to enroll patients with stage IV NSCLC with EGFR mutation and evaluate whether primary tumor resection after receiving the afatinib can prolong survival.
- Trial name
- NCT05215548
- Testing
- therapeutic thoracic surgery, Afatinib
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Non-small Cell Lung Cancer, Primary Neoplasm
Synapse 3D With Intravascular Indocyanine Green
With the advent of CT screening for lung cancer, an increasing number of NSCLCs are being detected at very early stages, and the demand for pulmonary segmentectomy is rising rapidly.
- Trial name
- NCT03953144
- Testing
- Synapse 3D Lung Modelling, IC-Green (ICG)
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Lung Cancer, Progression, Disease
The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer.
- Conditions
- Lung Cancer, Progression, Disease, Anesthesia
- Trial name
- NCT05663242
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Lung Cancer Metastatic, Surgical Resection
Primary Tumor Resection for M1a Stage Lung Cancer
This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1023. This study aims to explore the safety and efficacy of primary lesion resection in the treatment of M1a stage lung cancer…
- Trial name
- ECTOP-1023 (NCT06547710)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fudan University
Non-Small Cell Lung Cancer (NSCLC), Rehabilitation
Digital Rehabilitation With Wearable Monitors for Sequential Lung Cancer Resection
This is a prospective, open-label, parallel-group, 1:1 randomized controlled trial designed to evaluate whether a digital rehabilitation program integrated with wireless wearable continuous monitoring devices can shorten the time…
- Conditions
- Non-Small Cell Lung Cancer (NSCLC), Rehabilitation, Thoracic Surgery
- Trial name
- WEAR-MPLC (NCT07797075)
- Testing
- Wireless Wearable Vital Sign and Activity Monitor, Digital Pulmonary Rehabilitation Program, Standard ERAS Perioperative and Rehabilitation Care
- Where
- China
- Volunteers
- 222 people
- Sponsor
- West China Hospital
Lung Cancer, Stage IIIA-cN2
Molecular Signature From Tumor to Lymph Nodes
Mediastinal lymph node (LN) involvement (N2) in non-small cell lung cancer (NSCLC) concerns 15% of resectable tumors and is associated with a poor prognosis and an overall survival reaching 9 to 49%.
- Conditions
- Lung Cancer, Stage IIIA-cN2, Operated With Curative Intent, Primary Tumor Tissue Available
- Trial name
- N2-3S (NCT04677205)
- Where
- 12 sites in France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-Small Cell Lung Cancer, Epidermal Growth Factor Receptor
Bolstering Outcomes After Induction With Osimertinib Plus Chemotherapy Through Optimized Site-Directed Primary Tumor Therapy (BOOST Trial)
This is a single-arm, open-label, phase II study evaluating the clinical outcomes of local therapy (surgery or radiotherapy) to the primary tumor in patients with EGFR-mutant advanced non-small cell lung cancer (NSCLC) who have…
- Trial name
- BOOST (NCT07073365)
- Testing
- Local Therapy (Surgery or Radiotherapy)
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Pusan National University Hospital
Lung Cancer, Artifical Intelligence
AI-Assisted 3D Reconstruction for Lung Resection Planning
This prospective observational study aims to validate an artificial intelligence (AI)-based system for automated three-dimensional (3D) reconstruction of pulmonary anatomy from preoperative chest computed tomography (CT) scans in…
- Conditions
- Lung Cancer, Artifical Intelligence, Surgery for Primary Lung Cancer
- Trial name
- NCT07853157
- Testing
- AI-Based 3D Reconstruction
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- S. Andrea Hospital
Non Small Cell Lung Cancer
Primary Tumor Resection With Sintilimab and Chemotherapy in Advanced NSCLC
This study aims to evaluate whether resecting the primary tumor can improve the outcomes of treatment with sintilimab and chemotherapy in advanced EGFR/ALK-negative non-small cell lung cancer (NSCLC).
- Trial name
- SURGAN-ICI (NCT07177105)
- Testing
- Cytoreductive surgery, Immunochemotherapy
- Volunteers
- 118 people
- Sponsor
- Jianxing He