Clinical trials: Surgery of Breast Cancer
Breast Cancer
Effect of Midazolam Premedication Before Induction on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Surgery Due to Breast Cancer
Normally, higher levels of preoperational stress or anxiety affect behavior and recovery after the operation. Moreover, patients undergoing mastectomy are usually young women, and this demographic is known to experience higher…
- Trial name
- NCT01945476
- Testing
- midazolam premedication
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Breast Cancer, Chemotherapy Induced Peripheral Neuropathy (CIPN)
Simple Surgical Glove Compression to Prevent Chemotherapy-Induced Peripheral Neuropathy
To evaluate the preventive efficacy of a simple surgical glove compression technique in reducing the incidence and severity of Chemotherapy Induced Peripheral Neuropathy among patients receiving chemotherapy.
- Conditions
- Breast Cancer, Chemotherapy Induced Peripheral Neuropathy (CIPN), Neoadjuvant Therapy
- Trial name
- NCT07169864
- Testing
- Simple Surgical Glove Compression Technique
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Jinsong Lu
Breast Cancer, Shoulder Dysfunction
Effectiveness of a Visual Biofeedback Program Versus Conventional Physiotherapy on Shoulder Mobility, Strength, and Function in Women After Breast Cancer Surgery
This study aims to evaluate the effectiveness of a physiotherapy program incorporating visual biofeedback compared to a conventional physiotherapy program in improving shoulder function in women following breast cancer surgery.
- Trial name
- NCT07542106
- Testing
- Experimental Group: Physiotherapy + Visual Biofeedback
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Cancer Recurrence, Breast Cancer
Impact of the Intraoperative Use of Amines in Breast Cancer Surgery on Tumor Recurrence
Adrenergic receptors (alpha and beta) are expressed on breast cancer cells, and their stimulation has been shown in experimental studies to promote tumor proliferation and metastasis.
- Trial name
- MASTECTAMINE (NCT07624734)
- Testing
- collection of health data from electronic medical records
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Brain Metastasis, Bladder Cancer
Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases
For patients who have one or two metastases in the brain, the tumor(s) can often be removed with surgery to relieve symptoms from the tumor(s) and to improve survival.
- Conditions
- Brain Metastasis, Bladder Cancer, Breast Cancer, Cervical Cancer
- Trial name
- NCT00587964
- Testing
- Stereotactic Radiosurgery
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
CairnSurgical Breast Cancer Locator (BCL) Post-Market Study
This interventional, post-market, multicenter clinical investigation is designed to evaluate the performance of a custom-made medical device, "the Breast Cancer Locator (BCL)" in Subjects with non-palpable breast cancer, in…
- Trial name
- NCT06461663
- Testing
- Breast Cancer Locator Guided Breast Conserving Surgery
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 35 people
- Sponsor
- CairnSurgical, Inc.
Breast Cancer, Risk Reduction
Restore-B: A Trial Comparing Prepectoral Implant-based Breast Reconstruction With and Without Mesh
The goal of this feasibility randomised controlled clinical trial (RCT) is to compare mesh-assisted to no-mesh pre-pectoral implant based immediate breast reconstruction in women undergoing mastectomy for treatment of breast…
- Trial name
- NCT06112977
- Testing
- Prepectoral implant-based immediate breast reconstruction
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Oxford
Breast Cancer Invasive Nos, Primary Invasive Breast Cancer
A Prototype Tri-modal Imaging Device for Breast Cancer
Breast conservation surgery (BCS) is performed on patients with breast cancer with the intent to resect and completely remove the tumour while conserving as much of the surrounding normal tissue as possible.
- Trial name
- NCT02794064
- Testing
- Tri-modal imaging
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
HER2/Neu Positive, Stage IA Breast Cancer
Combination Chemotherapy and Paclitaxel Plus Trastuzumab in Treating Women With Palpable Breast Cancer That Can Be Removed by Surgery
This randomized phase III trial is studying giving fluorouracil together with epirubicin and cyclophosphamide followed by paclitaxel and trastuzumab to see how well it works compared with giving paclitaxel together with…
- Conditions
- HER2/Neu Positive, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT00513292
- Testing
- Cyclophosphamide, Epirubicin Hydrochloride, Laboratory Biomarker Analysis
- Where
- 115 sites in United States, Puerto Rico
- Volunteers
- 280 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
Does Scar Massage Improve Postoperative Pain and Function in Women With Breast Cancer?
All patients undergoing breast cancer surgery are left with scars which can significantly affect their physical and psychological well being.
- Trial name
- NCT00175344
- Testing
- Scar massage.
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Breast Cancer
Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
This pilot study will examine the impact of pre-operative Medical Reiki© on the psychosocial well-being and recovery of underserved women undergoing breast cancer surgery.
- Trial name
- NCT06524895
- Testing
- Medical Reiki
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Albert Einstein College of Medicine
Breast Cancer Female, Breast Cancer
Robotic vs. Open NSM for Early Stage Breast Cancer
This study evaluates the safety and effectiveness of the da Vinci SP Surgical System compared to Open NSM in Nipple Sparing Mastectomy procedures.
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Cancer, Early-Onset, Breast Disease
- Trial name
- SP NSM (NCT05720039)
- Testing
- Robotic NSM, Open NSM
- Where
- 15 sites in United States
- Volunteers
- 204 people
- Sponsor
- Intuitive Surgical
Breast Cancer
Pegylated Liposomal Doxorubicin and Docetaxel in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as liposomal doxorubicin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00524459
- Testing
- docetaxel, pegylated liposomal doxorubicin hydrochloride, conventional surgery
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Roswell Park Cancer Institute
Locoregional Analgesia in Breast Surgery
Double-blind Study to Assess effectIveness of Pectoral Nerves Block After Breast Surgery on Piritramide Consumption
The aims of this study is to compare the effectiveness of pecs block associated to a general anesthesia in terms of Piritramide consumption compared with a general anaesthesia alone and the chronic pain incidence in patients that…
- Trial name
- DESIGN (NCT02655965)
- Testing
- Ropivacaine, Clonidine, Sodium Chloride
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Jules Bordet Institute
Breast Cancer, Pain
Psychological and Social Factors and Risk Chronic Pain After Surgery in Women With Breast Cancer
Certain psychological and social factors may increase the risk of developing chronic pain after surgery. Evaluating these factors over time in patients who have undergone surgery for breast cancer may help doctors plan treatment…
- Conditions
- Breast Cancer, Pain, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- SDPM (NCT00466830)
- Testing
- questionnaire administration, management of therapy complications, psychosocial assessment and care
- Sponsor
- Institut Bergonié
Inflammatory Breast Cancer, Male Breast Cancer
Sunitinib Malate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide Before Surgery in Treating Patients With Stage IIB-IIIC Breast Cancer
This phase II trial studies how well giving sunitinib malate together with paclitaxel, doxorubicin hydrochloride, and cyclophosphamide before surgery works in treating patients with stage IIB-IIIC breast cancer.
- Conditions
- Inflammatory Breast Cancer, Male Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer
- Trial name
- NCT00513695
- Testing
- sunitinib malate, paclitaxel, doxorubicin hydrochloride
- Where
- 7 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Washington
Obesity, Breast Cancer
BCRL Prevention Pilot
The purpose of this study is to establish feasiblity of recruiting obese breast cancer survivors at the end of treatment, getting those survivors to lose weight and attend follow-up visits for 6 months.
- Trial name
- NCT01166672
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Breast Cancer
APBI Versus EBRT Therapy After Breast Conserving Surgery for Low-risk Breast Cancer
To assess the role of interstitial brachytherapy alone compared to whole breast irradiation in a defined low-risk group of invasive breast cancer or ductal carcinoma in situ concerning local failure (all ipsilateral local…
- Trial name
- NCT00402519
- Testing
- Accelerated partial breast irradiation, External beam whole breast irradiation
- Where
- 11 sites in Austria, Germany and 3 more
- Volunteers
- 1,300 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Breast Cancer
Metabolomic Profiling of Erector Spinae Plane Block* for Breast Cancer Surgery
Worldwide, breast cancer is the most common cancer among women, and its incidence and mortality rates are expected to increase significantly in the next years. It remains a major health problem.
- Trial name
- ESP (NCT04689945)
- Testing
- Morphine, Erector Spinae Block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Breast Cancer
Role of Axillary Lymph Node Dissection for Residual MACROMETASTASES After NEOADJUVANT Chemotherapy in Patients With HER2+ and Triple Negative Breast Cancer: The OPBC-11/MACRONAC Study
In this multicenter retrospective cohort study the aim is to determine the safety of omission of axillary lymph node dissection in patients with TNBC and HER2+ tumors with residual macrometastases (in the SLN/TAD/TAS or MARI…
- Trial name
- MACRONAC (NCT07546695)
- Testing
- Data Collection from medical records of from an already existing database "ONCOLOGICAL BREAST SURGERY DATABASE OF THE UNIVERSITY HOSPITAL OF BASEL" which was initiated in 2016.
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- University Hospital, Basel, Switzerland
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