Clinical trials: Surgery of Breast Cancer
Breast Cancer, Breast Neoplasms
ESPB and RIB for Pain Management Following Mastectomy Surgery
Postoperative pain is an important issue in patients underwent mastectomy and axillary dissection surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Cancer Female
- Trial name
- NCT04752150
- Testing
- Analgesia management; group ESPB and RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Breast Cancer, Nerve Block
Erector Spinae Block vs. Placebo Block Study
Regional anaesthesia combined with general anaesthesia has become common in the perioperative management of breast cancer surgery patients. Regional techniques have been recognised to provide excellent post-operative analgesia.
- Conditions
- Breast Cancer, Nerve Block, Regional Anesthesia, Neuromuscular Blockade
- Trial name
- NCT03978780
- Testing
- Erector spinae plane block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Women's College Hospital
Breast Cancer, Radiotherapy; Complications
Medial vs. Entire Supraclavicular Lymph Node Radiation Therapy for Patients With Invasive Breast Cancer
Locally advanced breast cancer has high-risk local regional recurrence after surgery. Radiotherapy could reduce the local regional recurrence and improve disease free survival and overall survival.
- Conditions
- Breast Cancer, Radiotherapy; Complications, Effect of Radiation Therapy
- Trial name
- SUCLANODE (NCT05059379)
- Testing
- Entire supraclavicular lymph node radiotherapy, Medial supraclavicular lymph node radiotherapy
- Where
- China
- Volunteers
- 1,650 people
- Sponsor
- Fudan University
Breast Cancer, Sentinel Lymph Node
Trop2-targeting NIR-II Molecular Probe for Breast Cancer Precise Surgery
Positive surgical margins are closely associated with local recurrence in breast-conserving surgery (BCS). Meanwhile, accurately assessing sentinel lymph node (SLN) metastasis is crucial for determining the extent of axillary…
- Conditions
- Breast Cancer, Sentinel Lymph Node, Margins of Excision
- Trial name
- NIR-II (NCT06713681)
- Testing
- TTP-ICG incubation solution
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Yunnan Cancer Hospital
Breast Cancer Female
Intraoperative Use of an Optical Coherence Tomography (OCT) Imaging System to Guide Additional Margin Cavity Shaves in Breast Conserving Surgery (BCS)
Female patients undergoing a breast conserving procedure will be consented for the excised breast tissue to be imaged on an investigational OCT-based device.
- Trial name
- NCT04314700
- Testing
- OCT- based investigational imaging device
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Perimeter Medical Imaging
Breast Cancer, Prostate Cancer
Kinetics of Perioperative Circulating DNA in Cancer Surgery
The aim of this study was to determine the kinetics of perioperative circulating DNA in three types of cancer. This first step will enable further studies comparing the potential impact of certain techniques or anesthetic…
- Conditions
- Breast Cancer, Prostate Cancer, Colon Cancer
- Trial name
- Periop ctDNA (NCT03284684)
- Testing
- Blood test
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Breast Cancer
Cryosurgery in Treating Women With Breast Lesions
RATIONALE: Cryosurgery kills cancer cells by freezing them. Cryosurgery followed by lumpectomy or mastectomy may be an effective treatment for breast lesions.
- Trial name
- NCT00020852
- Testing
- conventional surgery, cryosurgery
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer, Breast Pain
Post Mastectomy Pain Syndrome After Preoperative Stellate Ganglion Block for Breast Cancer Surgeries
This study investigate the effect of pre-operative ultrasound guided stellate ganglion block with local anesthetic on the frequency of neuropathic pain syndromes in the first 6-month post cancer breast surgeries with axillary…
- Trial name
- NCT04238377
- Testing
- Stellate Ganglion Block, Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer, Node-positive Breast Cancer
Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer
The purpose of the study is to determine the frequency of systemic metastasis in node positive breast cancer following chemotherapy and surgery. Participants will be asked to spend about 6 months in this study.
- Trial name
- NCT06833502
- Testing
- CT Scan
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Breast Cancer, Ductal Carcinoma in Situ
Intraoperative Gamma Camera for Breast Cancer Surgery
Aim: This study aims at evaluating the performances of an intraoperative gamma camera (field of view 10X10 cm), named CarolIReS, to detect axillary drainage and to assess the removal of sentinel lymph nodes (SLN) in breast…
- Trial name
- NCT00757302
- Testing
- SLN procedure (CarolIReS camera)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Strasbourg, France
Healthy
Cell Lines From High-Risk Breast Tissue
Background: Many risk factors for breast cancer have been identified, including family history, endocrine background, changes in breast tissue, cancer in one breast, radiation exposure, obesity and others.
- Trial name
- NCT00032201
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- National Cancer Institute (NCI)
Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Breast Cancer
Effects of SPSIP Block on Perioperative Inflammation and TLR4 in Breast Cancer Surgery
This study will investigate whether the serratus posterior superior intercostal plane (SPSIP) block improves postoperative recovery after breast cancer surgery. Participants will be randomly assigned to one of two groups.
- Conditions
- Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Breast Cancer, Toll-Like Receptors
- Trial name
- SPSIP-TLR4 (NCT07843212)
- Testing
- Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mucahide Emine Fidancı Kuas
Complications; Breast Prosthesis, Infection or Inflammation
Antibiotics and Tissue Expanders in Breast Reconstruction
This study is a randomized controlled non-blinded double arm study examining the effect of routine postoperative oral antibiotic therapy in preventing postoperative surgical site infections after breast reconstruction.
- Trial name
- NCT01899690
- Testing
- antibiotic
- Sponsor
- Emory University
Breast Cancer Female
Oral Microencapsulated Diindolylmethane in Treating Patients With Stage II-III Triple Negative, Androgen Receptor Positive Breast Cancer Who Have Undergone Chemotherapy and Surgery
This study is being done to find out whether a nutritional supplement, called BioResponse-DIM (BR-DIM [oral microencapsulated diindolylmethane]), improves the survival for women who have residual cancer cells following surgery…
- Trial name
- NCT01612910
- Testing
- oral microencapsulated diindolylmethane, laboratory biomarker analysis
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Mastectomy; Lymphedema, Breast Cancer
The Effect of Preoperative Education on Postoperative Healing Quality in Patients With Mastectomy
Breast cancer is one of the most common types of cancer today. Treatment is planned depending on various factors. The most common treatment option is surgery. Mastectomy is a type of surgery in which the entire breast is removed.
- Trial name
- NCT05914415
- Testing
- Supportive care and education before surgery
- Volunteers
- 70 people
- Sponsor
- Saglik Bilimleri Universitesi
Breast Disease, Breast Cancer
Comparison of Patient Reported Outcome Measures Using the BREAST-Q Questionnaire in Patients Undergoing Pre Versus Sub-pectoral Implant Based Immediate Breast Reconstruction.
The PROM Q study aims to compare patient reported outcome measures (PROMs) in patients undergoing mastectomy and immediate implant based breast reconstruction (IBR).
- Conditions
- Breast Disease, Breast Cancer, Patient Satisfaction, Surgery
- Trial name
- PROM-Q (NCT04842240)
- Testing
- Pre- or sub-pectoral implant based immediate breast reconstruction
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Pain, Chronic Disease
The Effect of Soy Protein on Post- Breast Cancer Surgery Pain
The incidence of chronic pain after breast cancer surgery (CPBCS) is high in women diagnosed with breast cancer. Similar to other chronic postoperative pain conditions, existing treatments for CPBCS do not always work.
- Conditions
- Pain, Chronic Disease, Breast Cancer
- Trial name
- NCT01047774
- Testing
- Isolated soy protein, Isolated milk protein
- Where
- 4 sites in Canada
- Volunteers
- 6 people
- Sponsor
- Dr. Yoram Shir
Malignant Neoplasm of Breast
Accelerated Partial Breast Irradiation Versus Standard or Hypofractionated Whole-Breast Irradiation, in Early Breast Cancer, After Breast-conserving Surgery
Radiotherapy has been confirmed as an important treatment breast-conserving surgery reducing the risk of any recurrence of breast cancer and breast cancer-related mortality in patients with early breast cancer.
- Trial name
- LAPIDARY (NCT04669873)
- Testing
- Active Comparator: Standard, Experimental 1: Hypofractionated radiotherapy, Experimental 2: Accelerated Partial Breast Irradiation
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Breast Cancer
Investigation of the Efficiency of Pain Neuroscience Education in Patients With Chronic Pain After Breast Cancer Surgery
Breast cancer is the most common type of cancer among women worldwide. Various side effects are seen after the treatments (surgery, chemotherapy, radiotherapy, etc.).
- Trial name
- NCT06052085
- Testing
- Pain Neuroscience Education, Biomedical Pain Education, Standard Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Breast Cancer, Lymphedema
Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer
This study will examine the frequency and severity of problems in women with breast cancer during the first year after initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Lymphedema, Physical Therapy, Shoulder
- Trial name
- NCT00027105
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
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