Clinical trials: Surgery of Breast Cancer
Breast Cancer
Epirubicin in Treating Women Who Are Undergoing Surgery for Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as epirubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00253500
- Testing
- pegfilgrastim, epirubicin hydrochloride, conventional surgery
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Case Comprehensive Cancer Center
Lymphedema, Lymphedema of Upper Arm
Microvascular Breast Reconstruction With Lymph Node Transfer
this study aims to evaluate the outcomes of simultaneous free abdominal flap \& vascularized lymph node transfer for both breast reconstruction and postmastectomy lymphedema
- Conditions
- Lymphedema, Lymphedema of Upper Arm, Mastectomy; Lymphedema
- Trial name
- NCT04246034
- Testing
- Microvascular Breast Reconstruction with Vascularized Lymph Node Transfer
- Sponsor
- Assiut University
Breast Cancer, Breast Neoplasms
Different Volumes of Erector Spinae Plane Block for Breast Surgery
Postoperative pain is an important issue in female patients underwent breast surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Diseases
- Trial name
- NCT05232084
- Testing
- Bupivacaine + Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Balance and Physical Activity Deficits After Breast Surgery
Physical Activity and Balance Changes in Operated Patients Because of Breast Cancer
Balance and physical activity deficits are theoretically expected in patients operated on for breast cancer. A significant decrease in the physical activity occurred, Their balance did not deteriorate in the follow-ups.
- Trial name
- NCT05566509
- Testing
- Breast excision
- Volunteers
- 112 people
- Sponsor
- Saglik Bilimleri Universitesi
Breast Cancer
A Prospective Clinical Study for Evaluation of Safe Resection Margin in Breast Conserving Surgery in Breast Cancer
Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has been used for breast cancer surgery such as sentinel lymph node (SLN) mapping and breast cancer localization.
- Trial name
- NCT02817334
- Testing
- indocyanine green
- Where
- South Korea
- Volunteers
- 149 people
- Sponsor
- National Cancer Center, Korea
Mastectomy, Rhomboid Intercostal Block
Effects of Rhomboid Intercostal Block on Postoperative Pain Management and Chronic Pain Incidence in Mastectomies
The goal of this clinical trial is to evaluate the effects of the Rhomboid Intercostal Block (RIB) on postoperative chronic pain prevalence at 3 months (primary outcome) and on acute pain control, total opioid consumption, and…
- Conditions
- Mastectomy, Rhomboid Intercostal Block, Chronic Pain Following Surgical Procedure for Cancer
- Trial name
- NCT06756048
- Testing
- Rhomboid Intercostal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Koç University
Breast Cancer
A Study of ZD1839 Effects on Cell Proliferation in Breast Cancer
This is a Phase II, randomised, double-blind, placebo-controlled study. Subjects with histologically-confirmed oestrogen receptor negative (ER-), progesterone receptor negative (PgR-) primary breast cancer breast cancer will be…
- Trial name
- NCT00252811
- Testing
- Gefitinib
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- AstraZeneca
Breast Cancer, HER2-negative Breast Cancer
A Study of the Impact of Endocrine Therapy on Surgical Outcomes in People With Lobular Breast Cancer
The purpose of this study is to look at how effective neoadjuvant (before surgery) endocrine therapy (NET) is in participants with invasive lobular carcinoma (ILC) who have breast-conserving surgery (BCS).
- Conditions
- Breast Cancer, HER2-negative Breast Cancer, HER2 Negative Breast Carcinoma, ER+ Breast Cancer
- Trial name
- NCT07483307
- Testing
- Neoadjuvant endocrine therapy
- Where
- 7 sites in United States
- Volunteers
- 176 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Omitting Sentinel Lymph Node Biopsy in Early-stage Breast Cancer
De-escalation in Axillary Surgery for Early-stage Breast Cancer
The goal of this clinical trial is to determine if the omission of sentinel lymph node biopsy is safe for early-stage breast cancer patients in our institution (Clinical Hospital Centre Rijeka).
- Trial name
- RIDES (NCT07098507)
- Testing
- sentinel lymph node biopsy, omission of sentinel lymph node biopsy
- Where
- Croatia
- Volunteers
- 620 people
- Sponsor
- Clinical Hospital Center Rijeka
Breast Cancer
The Use of a High-frequency Ultrasonic Knife in Breast Cancer Surgery
Background: Lymphatic stasis and seroma formation are common complications of axillary lymphadenectomy in breast cancer surgery.
- Trial name
- UKBC (NCT00996632)
- Testing
- ultrasonic knife (Ultracision®, Ethicon Endo Surgery), conventional diarthermy knife
- Where
- 2 sites in Italy
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Breast Cancer
Paclitaxel, Doxorubicin, and Cyclophosphamide With Or Without Carboplatin in Treating Women With Locally Advanced Breast Cancer That Can Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, doxorubicin, cyclophosphamide, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00589238
- Testing
- carboplatin, cyclophosphamide, doxorubicin hydrochloride
- Where
- 2 sites in Singapore
- Volunteers
- 16 people
- Sponsor
- National Cancer Centre, Singapore
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma
Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis
This phase III trial evaluates the effect of adding locoregional therapy (surgery and radiation) and metastasis-directed stereotactic body radiation therapy (SBRT) to standard systemic therapy following standard HER2-targeted…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma, Oligometastatic Breast Carcinoma
- Trial name
- NCT07578116
- Testing
- Biopsy Procedure, Biospecimen Collection, Breast Conservation Treatment
- Where
- 59 sites in United States
- Volunteers
- 562 people
- Sponsor
- SWOG Cancer Research Network
Breast Cancer
Role of Oncoplastic Breast Surgery In Breast Cancer Treatement
Role of Oncoplastic Breast Surgery In Breast Cancer Treatement
- Trial name
- NCT03273348
- Testing
- Oncoplastic breast surgery
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Cancer, Breast Surgery
Evaluation of the Effect of Antibiotic Prophylaxis During Lumpectomy for Breast Cancer: Prospective Randomised Double-blind Noninferiority Study of Placebo vs Cefazolin
The goal of this clinical trial is to determine whether preoperative antibiotic prophylaxis with cefazolin is necessary to prevent surgical site infections in adult women undergoing breast-conserving surgery (lumpectomy or…
- Conditions
- Breast Cancer, Breast Surgery, Surgical Site Infection (SSI), Surgical Site Infection Prevention
- Trial name
- PROPHY-SEIN (NCT07898943)
- Testing
- Cefazolin 2 g Infusion
- Where
- 33 sites in France
- Volunteers
- 1,600 people
- Sponsor
- University Hospital, Clermont-Ferrand
Breast Cancer
Accessory Joint and Neural Mobilizations in Shoulder After Breast Cancer Surgery. Randomized Clinical Trial.
The potential consequences after breast cancer surgery are joint pain and sensitive disorders, the main sign of which is alterations in shoulder mobility.
- Trial name
- NCT02366793
- Testing
- Accessory joint mobilization, Nerve mobilization
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Pain, Postoperative, Pain, Acute
SPSIPB for Breast Cancer Surgery
Acute postoperative pain after breast cancer surgery is usually moderate to severe, and inadequate postoperative pain management can significantly increase perioperative analgesic consumption, prolong hospital stay, and even…
- Conditions
- Pain, Postoperative, Pain, Acute, Opioid Consumption
- Trial name
- NCT06225908
- Testing
- Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Breast Cancer, Modified Radical Mastectomy
Use of Harmonic in Breast Surgery
To compare harmonic scalpel with electrocautery for outcomes i.e. estimated blood loss (EBL), operating time, drain Volume and drain Days, seroma formation, surgical site infection and postoperative pain in adult females…
- Trial name
- HMRM (NCT01587248)
- Testing
- Harmonic, electrocautery
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Aga Khan University
Breast Cancer, Morbid Obesity
Effects of Bariatric Surgery on Breast Density Improvement and Impact on Breast Cancer Risk in Severe Obese Patients
Breast cancer is the most common cancer in women in the US, and obese women have a 20% to 40% increase in the risk of developing breast cancer compared with normal-weight women.
- Conditions
- Breast Cancer, Morbid Obesity, Bariatric Surgery Candidate
- Trial name
- NCT04170335
- Testing
- Bariatric surgery
- Where
- United States
- Sponsor
- The Cleveland Clinic
Breast Cancer
Effect of Breast Implants om Mammography Screening
The purpose of the study is to survey how many women have breast implants in the mammography screening population and the effect of implants on the number and type of examinations and on costs.
- Trial name
- NCT05222100
- Testing
- Mammography screening
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Vastra Gotaland Region
Breast-Conserving Surgery
A Novel Intraoperative Fluorescence-guided System for Evaluating Margins During Breast-conserving Surgery for Breast Cancer
The goal of this clinical trial is to learn if a novel intraoperative fluorescence-guided system (EndoSCell Scanner) can help surgeons more accurately remove all cancerous tissue during breast-conserving surgery in female…
- Trial name
- NCT07352930
- Testing
- EndoSCell Scanner (ES Scanner) System
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Guangdong Provincial People's Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.