Clinical trials: Surgery of Breast Cancer
Mastectomy
Mastectomy in Ambulatory Breast Surgery
This is a prospective observational study, involving 550 mastectomies in Lorraine Institute of Oncology, to assess care patients management of ambulatory surgical compared to standard surgery procedure.
- Trial name
- MASTAMBU (NCT03003169)
- Testing
- Medical questionnaire
- Where
- France
- Volunteers
- 419 people
- Sponsor
- Institut de Cancérologie de Lorraine
Breast Cancer, Pain, Postoperative
Comparative Sensory Mapping of Regional Anesthesia Techniques in Breast Cancer Surgery
Various regional anesthesia techniques, either individually or in combination, can be utilized for analgesia in breast cancer surgery.
- Trial name
- NCT06911892
- Testing
- Group Serratus Anterior Plane Block, Group Parasternal Block, Group Interpectoral+Pectoserratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Samsun University
Taxane-induced Peripheral Neuropathy
Evaluation of the Efficacy of Compression With Tight Surgical Gloves in Patients With Taxane-based Therapy
In this study, the effect of compression therapy of the hands with tight surgical gloves to reduce peripheral neuropathy in adult patients during the application of taxanes will be evaluated.
- Trial name
- ComPrendo (NCT06464536)
- Testing
- Compression
- Where
- Switzerland
- Volunteers
- 114 people
- Sponsor
- St.Gallen University of Applied Sciences
Patient Satisfaction, Preoperative Anxiety
Reduction of Pre-operative Anxiety Using a Specially Designed Educational Program for Breast Cancer Patients Undergoing Surgery: a Randomized Controlled Trial
This study aims to find out that if a specially designed educational program can help in reduction of pre-operative anxiety in breast cancer patients undergoing surgery as a part of their treatment.
- Conditions
- Patient Satisfaction, Preoperative Anxiety, Anxiety
- Trial name
- PAUSDE (NCT05887856)
- Testing
- comprehensive educational program for reduction of Pre-Operative Anxiety
- Where
- Pakistan
- Volunteers
- 400 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Estrogen Receptor-negative Breast Cancer, Male Breast Cancer
Saracatinib in Treating Patients With Metastatic or Locally Advanced Breast Cancer That Cannot Be Removed By Surgery
This phase II trial is studying saracatinib to see how well it works in treating patients with metastatic or locally advanced breast cancer that cannot be removed by surgery.
- Conditions
- Estrogen Receptor-negative Breast Cancer, Male Breast Cancer, Progesterone Receptor-negative Breast Cancer, Recurrent Breast Cancer
- Trial name
- NCT00559507
- Testing
- saracatinib, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
SRG-514 Administered Intraoperatively to Patients Undergoing Breast-conserving Cancer Surgery
This is a multicenter, first-in-human (FIH), open label, Phase 1 dose escalation and recommended Phase 2 dose (RP2D) extension trial with a primary objective to define the RP2D of SRG-514 when administered intraoperatively to…
- Trial name
- NCT06300411
- Testing
- SRG-514
- Where
- 8 sites in United States
- Volunteers
- 25 people
- Sponsor
- SURGE Therapeutics
Breast Cancer
Cyclophosphamide and Docetaxel or Doxorubicin in Treating Women With Newly Diagnosed Breast Cancer That Can Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, docetaxel, and doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00801411
- Testing
- cyclophosphamide, docetaxel, doxorubicin hydrochloride
- Where
- 2 sites in Singapore
- Volunteers
- 318 people
- Sponsor
- National Cancer Centre, Singapore
Breast Cancer
Physiotherapy Program for Breast Cancer Women Following Surgery: A Pilot Clinical Trial
pilot study on physical therapy in women with breast cancer immediately following surgery
- Trial name
- NCT04894565
- Testing
- rehabilitation
- Where
- Saudi Arabia
- Volunteers
- 23 people
- Sponsor
- King Fahad Medical City
Breast Cancer, General Anaesthesia
Effect of Rocuronium on BIS Values
Aim of this trial is to define if Trend of Four (TOF) values after a bolus of rocuronium is correlated with Bispectral Index BIS values during standard general anaesthesia for breast surgery.
- Trial name
- NCT05681611
- Testing
- Rocuronium
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- University of Padova
Systemic Inflammatory Response Syndrome
Effect of Menstrual Cycle on Traumatic Systemic Response
It is aimed to evaluate pathophysiology of systemic responses to trauma via using interleukin (IL) -1 and IL-6 levels and determining timing of surgery through phases of menstrual cycle.
- Trial name
- NCT03283345
- Testing
- modified radical mastectomy
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Breast Cancer
MarginProbe, a Device for Intraoperative Assessment of Margin Status in Breast Conservation Surgery
The purpose of this study is to show that addition of device use to a routine breast cancer tumor excision procedure is beneficial and assists the surgeon in correctly determining the extent of excision.
- Trial name
- Pivotal (NCT00749931)
- Testing
- MarginProbe, Lumpectomy
- Where
- 21 sites in United States, Israel
- Volunteers
- 664 people
- Sponsor
- Dune Medical Devices
Breast Neoplasm, Pain
Effectiveness of a Modern Educational Intervention in Breast Cancer Patients
In addition to fatigue, pain is the most frequent and persistent symptom following breast cancer and breast cancer treatment. Despite the effectiveness of different physical therapy modalities, such as manual techniques, passive…
- Trial name
- EduCan (NCT03351075)
- Testing
- Standard physical therapy program, Modern educational program, Traditional biomedical educational program
- Where
- Belgium
- Volunteers
- 184 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer
Short and Long Term Effects of a Physical Therapy Program After Breast Cancer Surgery
Objectives: To evaluate the pressure pain threshold, shoulder biomechanics, cardiorespiratory function and the quality of life associated with the short and long-term physical therapy rehabilitation following breast cancer…
- Trial name
- NCT04116281
- Testing
- Rehabilitation after breast cancer surgery
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidade Federal de Sao Carlos
Breast Neoplasms
Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast Cancer
This phase II trial studies the effects of paclitaxel combined with phosphoinositide 3-kinase (PI3K) inhibitor BKM120 in patients with stage II or III breast cancer that is described as estrogen receptor-positive, human epidermal…
- Trial name
- NCT01953445
- Testing
- paclitaxel, BKM120
- Sponsor
- Washington University School of Medicine
Anxiety Disorder, Breast Cancer
Hypnosis in Reducing Pain and Other Side Effects in Women Undergoing Surgery for Breast Cancer
RATIONALE: Hypnosis may be effective in reducing pain and other side effects in women undergoing surgery for breast cancer. PURPOSE: This clinical trial is studying how well hypnosis works in reducing pain and other side effects…
- Conditions
- Anxiety Disorder, Breast Cancer, Nausea and Vomiting, Pain
- Trial name
- NCT00748267
- Testing
- questionnaire administration, hypnotherapy, therapeutic conventional surgery
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Breast Cancer
Role of Axillary Lymph Node Dissection for Residual MACROMETASTASES After NEOADJUVANT Chemotherapy in Patients With HER2+ and Triple Negative Breast Cancer: The OPBC-11/MACRONAC Study
In this multicenter retrospective cohort study the aim is to determine the safety of omission of axillary lymph node dissection in patients with TNBC and HER2+ tumors with residual macrometastases (in the SLN/TAD/TAS or MARI…
- Trial name
- MACRONAC (NCT07546695)
- Testing
- Data Collection from medical records of from an already existing database "ONCOLOGICAL BREAST SURGERY DATABASE OF THE UNIVERSITY HOSPITAL OF BASEL" which was initiated in 2016.
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer
Music and Surgery Associated With Relationship and Satisfaction
In this study, the investigators want to check whether it has a direct effect on the participants first, and secondly, whether it affects the relationship between the patient and the doctor or treatment satisfaction, by reducing…
- Trial name
- MARS (NCT04555057)
- Testing
- Music therapy
- Where
- South Korea
- Volunteers
- 304 people
- Sponsor
- Asan Medical Center
Breast Cancer
Outcome of Neo-adjuvant Chemotherapy Followed by Breast Conservative Surgery in Breast Cancer in Upper Egypt
Systemic chemotherapy along with radiotherapy has been successfully used to post-operatively manage patients following tumour resection in breast cancer.
- Trial name
- NCT03696004
- Testing
- FEC-100
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Assiut University
Breast Cancer
Effects of Expectations and Body Image in Breast Reconstruction
A breast reconstruction after mastectomy, either due to breast cancer or a high lifetime risk for cancer, is performed to increase the patient's quality of life.
- Trial name
- NCT04714463
- Testing
- Implant-based breast reconstruction, Autologous breast reconstruction, Combined methods
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Vastra Gotaland Region
Breast Conserving Surgery
Evaluation of a New Technique to Fill the Defect Generated After Conservative Surgery in Breast Cancer
The placement of a small silicone prosthesis in the partial defects generated by conservative breast cancer surgery improves the aesthetic result, compared to the usual surgical technique, in a safe and reproducible way and…
- Trial name
- PROSILMA (NCT04092842)
- Testing
- Silicone prosthesis, Usual practice
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
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