Clinical trials: Surgery-first
Breast Implant; Complications, Infection or Inflammation
Histological Analysis of AlloMend® Acellular Dermal Matrix Used in Breast Implant Surgeries
This is a prospective, histologic analysis of biopsied tissue obtained from participants who have undergone a pre-pectoral breast reconstruction or augmentation surgery with expander placement and AlloMend® Acellular Dermal…
- Trial name
- NCT05744414
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AlloSource
Reconstruction of First Web Space
Reconstruction of First Web Space After Trauma and Burn
assess and compare the functional and aesthetic outcomes of different surgical techniques used for reconstruction of post-traumatic and post-burn first web space obliteration.
- Trial name
- NCT07762404
- Testing
- Reconstruction of post burn first web space obliteration in hand, First web space Reconstruction, Reconstruction of first web space
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pregnancy, Unwanted
Self-Administered Lidocaine Gel for Pain Management With First Trimester Surgical Abortion: A Randomized Controlled Trial
Despite global efforts to decrease discomfort during surgical abortion, pain remains a limiting factor in where and how procedures are performed.
- Trial name
- SALSA (NCT02447029)
- Testing
- vaginal 2% Xylocaine, standard lidocaine paracervical block
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Stanford University
Small Pupil, Cataract
Efficacy of the Canabrava/s Pupil Expansion Device in Cataract Surgery With Small Pupils: The First 30 Cases
To evaluate the intraoperative stability, safety and overall efficacy of the Canabrava Ring (AJL - SPAIN) when used to expand pupils with less diameter than 5 mm and pupils with sphincter synechiae.
- Trial name
- NCT03206983
- Testing
- Cana's Ring
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Santa Casa de Misericórdia de Belo Horizonte
Abortion in First Trimester
Nitrous Oxide for Pain Management of First Trimester Surgical Abortion
The purpose of this research is to study the effect of nitrous oxide on pain felt by women having a surgical termination at less than 11 weeks compared to pain felt by women receiving oral pain medications.
- Trial name
- NAB (NCT02096575)
- Testing
- Nitrous oxide administration
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Cervical Ripening
Misoprostol Versus Effox as Cervical Ripening Agent Prior Surgical Evacuation
Ninety healthy pregnant women candidate for surgical evacuation after confirming 1st trimester pregnancy loss were enrolled in the study.
- Trial name
- NCT02738177
- Testing
- Misoprostol, Isosorbide-5-mononitrate, misoprostol and Isosorbide-5-mononitrate
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgical Site Infection
Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors
Objective: To investigate if the use of the newly designed Alexis O Retractor leads to improved intra-operative and post-operative surgical outcomes in the setting of planned elective Caesarean Sections.
- Trial name
- NCT02685696
- Testing
- Alexis O Retractor, Metal Retractor
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Bariatric Surgery Candidate, Laparoscopic Sleeve Gastrectomy
Outcomes of Laparoscopic Sleeve Gastrectomy
The aim of this study is to assess 5 year long-term outcomes of laparoscopic sleeve gastrectomy emphasizing weight loss and modification of comorbidities such as type 2 diabetes mellitus, hypertension and gastroesophageal reflux…
- Conditions
- Bariatric Surgery Candidate, Laparoscopic Sleeve Gastrectomy, Obesity, Morbid
- Trial name
- NCT03983122
- Testing
- Laparoscopic sleeve gastrectomy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Biliary Colic, Cholecystitis
Initial Experience With a New Laparoscopic Based Robotically Assisted Surgical System for Cholecystectomy
The Senhance™ surgical robotic system, previously known as Telelap Alf-X (TransEnterix, Morrisville, NC, USA) has recently become available in the UK.
- Trial name
- NCT03380572
- Testing
- Senhance Assisted Cholecystectomy, Laparoscopic Cholecystectomy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Deformity of Nasal Cartilage
Effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty
The purpose of this research is to determine the effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty on First Impressions and Quality of Life determined by using the FACE-Q Scale.
- Trial name
- NCT04169308
- Testing
- Restylane-L® Filler injection
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DeNova Research
Hallux Valgus
Can Hypermobility of First Ray Affect Surgical Treatment of Hallux Valgus
Hallux valgus can be associated with hypermobility of 1st ray. Surgical decision for hallux valgus can be affected by hyper mobility of 1st ray so our clinical trial involved patients with bilateral hallux valgus were planned to…
- Trial name
- NCT05051709
- Testing
- Corrective osteotomy, Fusion of First ray
- Where
- Iraq
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Missed Abortion
Buccal Versus Vaginal Misoprostol in Surgical Termination of the First Trimester Missed Abortion in Erbil
The purpose of this study is to determine the effectiveness of buccal misoprostol and comparing this with vaginal route of the same drug.
- Trial name
- NCT00892229
- Testing
- Misoprostol (given buccally), Misoprostol (given vaginally)
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Pain, Surgical Abortion
Paracervical Block in First Trimester Surgical Abortions
The investigators primary objective is to study the analgesic effects of combined ketorolac and lidocaine in a paracervical block compared to preoperative ibuprofen followed by intra-operative paracervical block with lidocaine…
- Trial name
- NCT00617097
- Testing
- lidocaine, ketorolac and lidocaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anxiety, Heart Rate Variability (HRV)
Anxiety and Physiological Responses in Ambulatory Surgery
This study aims to investigate the effects of music intervention on subjective anxiety and physiological indicators, including heart rate, blood pressure, and heart rate variability, in first-time ambulatory surgery patients, and…
- Conditions
- Anxiety, Heart Rate Variability (HRV), Heart Rate, Blood Pressure
- Trial name
- NCT07476820
- Testing
- Self-selected Music intervention, Fixed-music Music intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Da-Yeh University
Patella Dislocation Recurrent, Children, Only
Assessment of Knee Flexor Muscles Strength in Patients With Patellar Instability
The study enrolled 33 patients with confirmed recurrent patellar dislocation, including 6 patients with bilateral involvement. In the study group, both side hamstring muscle were evaluated at the velocities of 60 and 180 deg/s…
- Trial name
- NCT04838158
- Testing
- Isokinetic measurements
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Myopia, Hyperopia
Creating LASIK Flaps With the LenSx Femtosecond Laser
This will be a prospective, single-center clinical trial of up to 50 eyes of subjects scheduled to undergo LASIK surgery requiring an initial corneal flap. Subjects will be screened for eligibility.
- Trial name
- NCT01556893
- Testing
- LenSx Laser
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alcon LenSx, Inc.
Skin Cancer, Skin Wound
Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery
This research study aims to understand whether visual and written education on wound appearance can improve patients' experience and understanding of what their wound will look like following dermatologic surgery.
- Trial name
- NCT05643755
- Testing
- Preoperative image-based education
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity, Morbid
Safe and Easy Access Technique for the First Trocar in Laparoscopic Obesity Surgery
Laparoscopic surgery has become very popular and standard in many indications after advancements of technique. Various methods have been used in first entry to the abdomen.
- Trial name
- NCT03015935
- Testing
- visual-assisted entry, Veress entry
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Induced Abortion
Is Oxytocin Given During Surgical Procedure for Abortion Before 12 Weeks of Pregnancy Useful?
This is a randomized, single-blind study using oxytocin 5U i.v. during surgical abortion in one arm of the study, and no medication in the other arm of the study.
- Trial name
- oxystudien (NCT00540748)
- Testing
- oxytocin
- Where
- Norway
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Asker & Baerum Hospital
First Trimester Abortion
A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions
This study, a double blinded randomized controlled trial, is being done to compare side effects of commonly used antibiotic regimens prior to same day abortion procedures.
- Trial name
- NCT02756403
- Testing
- Azithromycin, Doxycycline, Metronidazole
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute